Angiolymphoid hyperplasia with eosinophilia of the auricle: progression of histopathological changes

2006 ◽  
Vol 120 (5) ◽  
pp. 411-413 ◽  
Author(s):  
K G Effat
Keyword(s):  
Endothelial Cells ◽  
Differential Diagnosis ◽  
Inflammatory Cell ◽  
Rare Condition ◽  
Inflammatory Cell Infiltrate ◽  
Histopathological Changes ◽  
Cell Infiltrate ◽  
Histopathological Features ◽  
Angiolymphoid Hyperplasia With Eosinophilia ◽  
Angiolymphoid Hyperplasia

Angiolymphoid hyperplasia with eosinophilia is a rare condition that demonstrates dermal or subcutaneous proliferation of endothelial cells associated with an inflammatory cell infiltrate. A case is reported, with emphasis on the histopathological features on repeated biopsies. The report serves to stress the importance of considering this condition in the differential diagnosis of lesions in and around the ear.

Deep Penetrating Nevus: A Review

2011 ◽  
Vol 135 (3) ◽  
pp. 321-326
Author(s):  
Boštjan Luzar ◽  
Eduardo Calonje
Keyword(s):  
Differential Diagnosis ◽  
Inflammatory Cell ◽  
Data Sources ◽  
Inflammatory Cell Infiltrate ◽  
Melanocytic Lesion ◽  
Cell Infiltrate ◽  
Nuclear Pleomorphism ◽  
Cytologic Atypia ◽  
Mononuclear Inflammatory Cell

Abstract Context.—Deep penetrating nevus is a distinctive melanocytic lesion that may simulate melanoma both clinically and histologically. Objective.—To review clinical and histologic features of deep penetrating nevi and discuss their differential diagnosis, especially regarding melanoma. Data Sources.—The literature on deep penetrating nevi is reviewed and supplemented by our experiences with deep penetrating nevi. Conclusions.—One or more disturbing histologic features may frequently be found in deep penetrating nevi, including asymmetry, plump but fairly regular nests of melanocytes in the dermis, cytologic atypia with some nuclear pleomorphism, a small to medium-sized eosinophilic nucleolus, absence of maturation, occasional presence of normal dermal mitoses, and a patchy mononuclear inflammatory cell infiltrate. Although unusual, such histologic features should not be regarded as a sign of malignancy in deep penetrating nevi.

scholarly journals Higher Number of EBI3 Cells in Mucosal Chronic Hyperplastic Candidiasis May Serve to Regulate IL-17-Producing Cells

2021 ◽  
Vol 7 (7) ◽  
pp. 533
Author(s):  
Ailish Williams ◽  
Helen Rogers ◽  
David Williams ◽  
Xiao-Qing Wei ◽  
Damian Farnell ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Oral Lichen Planus ◽  
Inflammatory Cell ◽  
Candida Infection ◽  
Inflammatory Cell Infiltrate ◽  
T Helper ◽  
Cell Infiltrate ◽  
High Prevalence ◽  
Squamous Cell Papilloma ◽  
Oral Lichen

Previous research into the inflammatory cell infiltrate of chronic hyperplastic candidosis (CHC) determined that the immune response is primarily composed of T cells, the majority of which are T helper (CD4+) cells. This present investigation used immunohistochemistry to further delineate the inflammatory cell infiltrate in CHC. Cells profiled were those expressing IL-17A cytokine, EBI3 and IL-12A subunits of the IL-35 cytokine, and FoxP3+ cells. Squamous cell papilloma (with Candida infection) and oral lichen planus tissues served as comparative controls to understand the local immune responses to Candida infection. The results demonstrated that Candida-induced inflammation and immune regulation co-exist in the oral mucosa of CHC and that high prevalence of cells expressing the EBI3 cytokine subunit may play an important role in this regulation. This balance between inflammation and immune tolerance toward invading Candida in the oral mucosa may be critical in determining progress of infection.

scholarly journals DNA Vaccines: MHC II-Targeted Vaccine Protein Produced by Transfected Muscle Fibres Induces a Local Inflammatory Cell Infiltrate in Mice

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e108069 ◽  
Author(s):  
Tom-Ole Løvås ◽  
Jo C. Bruusgaard ◽  
Inger Øynebråten ◽  
Kristian Gundersen ◽  
Bjarne Bogen
Keyword(s):  
Inflammatory Cell ◽  
Dna Vaccines ◽  
Inflammatory Cell Infiltrate ◽  
Muscle Fibres ◽  
Cell Infiltrate ◽  
Mhc Ii

Immunohistochemical characterization of seminoma and its inflammatory cell infiltrate

1987 ◽  
Vol 18 (5) ◽  
pp. 511-520 ◽  
Author(s):  
Debra A. Bell ◽  
Thomas J. Flotie ◽  
Atul K. Bhan
Keyword(s):  
Inflammatory Cell ◽  
Inflammatory Cell Infiltrate ◽  
Cell Infiltrate

Angiolymphoid hyperplasia with eosinophilia

1990 ◽  
Vol 104 (12) ◽  
pp. 977-979 ◽  
Author(s):  
J. F. Sharp ◽  
M. J. C. Rodgers ◽  
F. B. Macgregor ◽  
C. J. Meehan ◽  
K. McLaren
Keyword(s):  
Neck Region ◽  
Rare Condition ◽  
Surgical Removal ◽  
External Ear ◽  
Disease Entity ◽  
Peripheral Eosinophilia ◽  
Head And Neck Region ◽  
Angiolymphoid Hyperplasia With Eosinophilia ◽  
Angiolymphoid Hyperplasia ◽  
Unusual Condition

AbstractAngiolymphoid hyperplasia with eosinophilia is a rare condition and is poorly recognized in the otolaryngological literature. The condition is characterized by the appearance of cutaneous nodules within the head and neck region especially around the external ear. Variable lymphadenopathy and peripheral eosinophilia can occur and the condition can mimic neoplasia. It is important to be aware of this disease entity in order to avoid overtreatment. Surgical removal is the treatment of choice; however, this often multilobulated and poorly delineated lesion often precludes initial wide excision and local recurrence is common.We present three cases of this unusual condition and a brief resumé of the literature.

Characterisation of the inflammatory cell infiltrate in chronic hyperplastic candidosis of the oral mucosa

1997 ◽  
Vol 26 (2) ◽  
pp. 83-89 ◽  
Author(s):  
D. W. Williams ◽  
A. J. C. Potts ◽  
M. J. Wilson ◽  
J. B. Matthews ◽  
M. A. O. Lewis
Keyword(s):  
Oral Mucosa ◽  
Inflammatory Cell ◽  
Inflammatory Cell Infiltrate ◽  
Cell Infiltrate
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