Influenza A (H1N1): a rare cause of deafness in two children

2012 ◽  
Vol 126 (12) ◽  
pp. 1274-1275 ◽  
Author(s):  
A A Alsanosi
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Case Reports ◽  
Rare Complication ◽  
Swine Flu ◽  
Review Of The Literature ◽  
Chain Reaction ◽  
Influenza A H1n1 ◽  
Polymerase Chain ◽  
Bilateral Deafness

AbstractObjective:We report deafness occurring as an extremely rare complication of influenza A caused by the H1N1 virus (‘swine flu’), in two children.Methods:Case reports and review of the literature concerning influenza A (H1N1) and acquired viral infection causing deafness.Results:Two children with normal hearing developed bilateral deafness following influenza A (H1N1). The diagnosis was confirmed using polymerase chain reaction. Both patients were treated with oseltamivir.Conclusion:Following a review of the literature, these two patients appear to be the first reported cases of bilateral deafness following influenza A (H1N1).

Validation of a polymerase chain reaction–oligochromatography test for detection of influenza A (H1N1) 2009 virus

2012 ◽  
Vol 72 (2) ◽  
pp. 144-149 ◽  
Author(s):  
Loreto Fuenzalida ◽  
Cristina Prat ◽  
Silvia Blanco ◽  
Albert Bas ◽  
M.J. Domínguez ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Influenza A ◽  
Chain Reaction ◽  
Influenza A H1n1 ◽  
Polymerase Chain

scholarly journals Seroprevalence and Molecular Detection of Influenza A Virus (H1N1) in Sulaimani Governorate-Iraq

2022 ◽  
Vol 6 (1) ◽  
pp. 1-6
Author(s):  
Kaziwa Ahmad Kaka alla ◽  
Salih Ahmed Hama
Keyword(s):  
Employment Status ◽  
Influenza A ◽  
H1n1 Virus ◽  
Previous History ◽  
Reverse Transcription Pcr ◽  
Influenza A H1n1 ◽  
History Of ◽  
Polymerase Chain ◽  
Pcr Techniques ◽  
Positive Results

Influenza A (H1N1) virus is now rapidly scattering across the world. Early detection is one of the most effective measures to stop the further spread of the virus. The current study was aimed to detect influenza A (H1N1) serologically and by polymerase chain reaction (PCR) techniques. From September 2020 to June 2021, three hundred nasopharyngeal swabs and blood samples were collected from Hiwa and Shahid Tahir Hospitals in Sulaimani city. Obtained results revealed that 23.3% of the tested patients were seropositive anti-IgG for Influenza A, while 13.3% showed anti-IgM seropositive results although 10% of the tested cases were with both anti-IgG and anti-IgM seropositive results. Gender, residency, and flu symptoms showed no significant relations with seropositive results (p<0.05) whereas valuable relations were found between seropositive observations and smoking, the previous history of chronic diseases as well as employment status (p<0.05). It was concluded that hematologic investigations (CBC) were not dependable if H1N1 diagnosis and detection. Only 1% of the tested samples showed positive results for influenza A (H1N1) RNA using reverse transcription-PCR.

Outcomes of a Negative Rapid Influenza Diagnostic Test in Pregnant Women

2018 ◽  
Vol 36 (01) ◽  
pp. 090-096
Author(s):  
Phinnara Has ◽  
Kelly Fitzgerald ◽  
Brenna Hughes ◽  
Ilina Datkhaeva
Keyword(s):  
Pregnant Women ◽  
Diagnostic Test ◽  
Influenza A ◽  
Antiviral Treatment ◽  
False Negative ◽  
Chain Reaction ◽  
True Negative ◽  
Influenza A H1n1 ◽  
Polymerase Chain ◽  
To Receive

Objective The objective of this study was to evaluate the negative predictive value (NPV) of a rapid influenza diagnostic test (RIDT) compared with polymerase chain reaction (PCR) in pregnant women. Study Design Retrospective cohort study of pregnant women with a negative RIDT followed by confirmatory PCR for influenza A, H1N1, and B during the influenza seasons from 2012 to 2015. Results The NPV of the RIDT was 85.4% (211 of 247), 93.5% (231 of 247), and 97.9% (242 of 247) for influenza A, H1N1, and B, respectively. Antiviral treatment was administered to 47.2% (17 of 36) of women with a false-negative RIDT for influenza A compared with 9.0% (19 of 211) of women with a true-negative RIDT (p< 0.001). Patients were more likely to receive antiviral treatment if they were feverish (adjusted odds ratio [aOR]: 6.05, 95% confidence interval [CI]: 1.83–20.03), had cough (aOR: 6.43, 95% CI: 1.06–39.26), dyspnea (aOR: 6.41, 95% CI: 1.63–25.29), or had a subsequently positive PCR (aOR: 9.41, 95% CI: 3.13–28.31). Conclusion Up to 14.5% of women with a negative RIDT in pregnancy had positive influenza A by PCR of whom more than half did not receive antiviral treatment.

scholarly journals Pathologic Findings in Novel Influenza A (H1N1) Virus (“Swine Flu”) Infection

2010 ◽  
Vol 133 (3) ◽  
pp. 380-387 ◽  
Author(s):  
Sanjay Mukhopadhyay ◽  
Abraham T. Philip ◽  
Robert Stoppacher
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Swine Flu ◽  
Influenza A H1n1 ◽  
Pathologic Findings ◽  
Novel Influenza A
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