Trichobilharzia ocellata: chemical stimuli of duck skin for cercarial attachment

Parasitology ◽  
1988 ◽  
Vol 96 (3) ◽  
pp. 507-517 ◽  
Author(s):  
W. Feiler ◽  
W. Haas

SUMMARYTrichobilharzia ocellatacercariae attach readily to the foot skin of their duck host, but poorly to preen-gland contents. The attachment to duck foot disappears when the skin surface lipids are extracted, and can be restored by reapplication of the lipids to the skin. Hydrophilic skin extracts are without any effect. Thin-layer chromatographic fractionation of duck-foot skin surface lipids reveals cholesterol and ceramides as attachment stimuli. A stimulation of cercarial attachment by these hydrophobic host signals is supported by the host identification pattern of the cercariae, which secures a close contact with encountered substrates.

1970 ◽  
Vol 48 (3) ◽  
pp. 373-378 ◽  
Author(s):  
T. NIKKARI ◽  
M. VALAVAARA

SUMMARY The effect of five androgens on the activity of the sebaceous glands of female rats hypophysectomized at 3–4 weeks of age was studied by determining the rate of production and palmitate: stearate ratio of the skin surface lipids. Both of these values reflected the stimulation of the sebaceous glands by androgens, but the palmitate: stearate ratio appeared to be a more sensitive index of low androgenic activity than the production rate. The response of the sebaceous glands to the androgens tested increased in the order (the relative potencies were calculated from the palmitate: stearate ratios): androstenedione, 17; dehydroepiandrosterone, 33; androstanolone, 48; androstanediol, 91; and testosterone propionate, 100. Prolactin did not enhance the stimulation of the sebaceous glands induced by testosterone propionate.


1975 ◽  
Vol 37 (6) ◽  
pp. 909-917 ◽  
Author(s):  
Tokuji HIROWATARI

1964 ◽  
Vol 18 ◽  
pp. 671-680 ◽  
Author(s):  
T. Nikkari ◽  
E. Haahti ◽  
Artturi I. Virtanen ◽  
I. Wadsö ◽  
Lennart Nilsson

1995 ◽  
Vol 13 (4) ◽  
pp. 307-321 ◽  
Author(s):  
Peter Clarys ◽  
Andre Barel

2020 ◽  
Author(s):  
Helen Louise Orbell ◽  
Nick J Cave ◽  
Katharina Parry ◽  
Craig E Griffin

Abstract Background – The skin barrier is important in the pathogenesis of atopic dermatitis and stratum corneum lipids have a critical role. Skin surface lipids have been largely overlooked but also contribute to barrier function. An untargeted approach was used to compare the skin surface lipids from atopic and non-atopic West Highland White terrier dogs. The primary hypothesis was that a difference in the lipidome of atopic and non-atopic dogs would be found and the secondary hypothesis was that affected and unaffected skin would differ in lipid profile.Results – Thirty-nine dogs were classified into one of four disease status groups based on strict criteria. Samples for lipid analysis were collected from affected and unaffected skin, and liquid chromatography/mass spectrometry found 421 lipid soluble features. Ten lipids were positively identified. Statistical analysis could not distinguish between non-atopic and atopic dogs. Partial least squares-discriminant analysis revealed a difference in the lipid profiles from affected and non-affected skin irrespective of disease status. Conclusions – An untargeted approach found a large array of unidentified lipids from the skin surface. There was a difference in the lipidome between affected and unaffected skin that was not related to disease status. Investigation into the lipidome of the skin surface in health and disease is an emerging area of research which could have clinical and therapeutic applications.


1974 ◽  
Vol 17 (3) ◽  
pp. 372-376 ◽  
Author(s):  
R.C. Noble ◽  
M.L. Cuouchman ◽  
J.H. Moore

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