OP196 Clinical Decision Support Systems (CDSS) For Antibiotic Management: Factors Limiting Sustainable Digital Transformation

Author(s):  
Mah Laka ◽  
Adriana Milazzo ◽  
Drew Carter ◽  
Tracy Merlin

IntroductionClinical decision support systems (CDSS) are being developed to support evidence-based antibiotic prescribing and reduce the risk of inappropriate or over-prescribing; however, adoption of CDSS into the health system is rarely sustained. We aimed to understand the implementation challenges at a macro (policymakers), meso (organizational) and micro-level (individual practices) to identify the drivers of CDSS non-adoption.MethodsWe have adopted a mixed-method study design which comprised of: (i) systematic review and meta-analysis to assess the impact of CDSS on appropriate antibiotic prescribing, (ii) Online survey of clinicians in Australia from hospitals and primary care to identify drivers of CDSS adoption and (iii) in-depth interviews with policymakers to evaluate policy-level challenges and opportunities to CDSS implementation.ResultsCDSS implementation can improve compliance with antibiotic prescribing guidelines, with a relative decrease in mortality, volume of antibiotic use and length of hospital stay. However, CDSS provision alone is not enough to achieve these benefits. Important predictors of clinicians’ perception regarding CDSS adoption include the seniority of clinical end-users (years), use of CDSS, and the care setting. Clinicians in primary care and those with significant clinical experience are less likely to use CDSS due to a lack of trust in the system, fear of comprising professional autonomy, and patients’ expectations. Lack of important policy considerations for CDSS integration into a multi-stakeholder healthcare system has limited the organizational capacity to foster change and align processes to support the innovation.ConclusionsThese results using multiple lines of evidence highlight the importance of a holistic approach when undertaking health technology management. There needs to be system-wide guidance that integrates individual, organizational and system-level factors when implementing CDSS so that effective antibiotic stewardship can be facilitated.

Author(s):  
Mah Laka ◽  
Adriana Milazzo ◽  
Tracy Merlin

The study evaluated individual and setting-specific factors that moderate clinicians’ perception regarding use of clinical decision support systems (CDSS) for antibiotic management. A cross-sectional online survey examined clinicians’ perceptions about CDSS implementation for antibiotic management in Australia. Multivariable logistic regression determined the association between drivers of CDSS adoption and different moderators. Clinical experience, CDSS use and care setting were important predictors of clinicians’ perception concerning CDSS adoption. Compared to nonusers, CDSS users were less likely to lack confidence in CDSS (OR = 0.63, 95%, CI = 0.32, 0.94) and consider it a threat to professional autonomy (OR = 0.47, 95%, CI = 0.08, 0.83). Conversely, there was higher likelihood in experienced clinicians (>20 years) to distrust CDSS (OR = 1.58, 95%, CI = 1.08, 2.23) due to fear of comprising their clinical judgement (OR = 1.68, 95%, CI = 1.27, 2.85). In primary care, clinicians were more likely to perceive time constraints (OR = 1.96, 95%, CI = 1.04, 3.70) and patient preference (OR = 1.84, 95%, CI = 1.19, 2.78) as barriers to CDSS adoption for antibiotic prescribing. Our findings provide differentiated understanding of the CDSS implementation landscape by identifying different individual, organisational and system-level factors that influence system adoption. The individual and setting characteristics can help understand the variability in CDSS adoption for antibiotic management in different clinicians.


2021 ◽  
Author(s):  
Hector Acosta-Garcia ◽  
Ingrid Ferrer-López ◽  
Juan Ruano-Ruiz ◽  
Bernardo Santos-Ramos ◽  
Teresa Molina-López

Abstract Background Computerized clinical decision support systems are used by clinicians at the point-of-care to improve quality of healthcare processes (prescribing error prevention, adherence to clinical guidelines...) and clinical outcomes (preventive, therapeutic, and diagnostics). Attempts to summarize results of computerized clinical decision support systems to support prescription in primary care have been challenging, and most systematic reviews and meta-analyses failed due to an extremely high degree of heterogeneity present among the included primary studies. The aim of our study will be to synthesize the evidence, considering all methodological factors that could explain these differences, and to build an evidence and gap map to identify important remaining research questions. Methods A literature search will be conducted from January 2010 onwards in Medline, Embase, The Cochrane Library and Web of Science databases. Two reviewers will independently screen all citations, full-text and abstract data. The study methodological quality and risk of bias will be appraised using appropriate tools if applicable. A flow diagram with the screened studies will be presented, and all included studies will be displayed using interactive evidence and gap maps. Results will be reported in accordance with recommendations from The Campbell Collaboration on the development of evidence and gap maps. Discussion Evidence behind computerized clinical decision support systems to support prescription use in primary care, has so far been difficult to be synthesized. Evidence and gap maps represent an innovative approach that has emerged and is increasingly being used to address a broader research question, where multiple types of intervention and outcomes reported may be evaluated. Broad inclusion criteria have been chosen with regards to study designs, in order to collect all available information. Regarding the limitations we will only include English and Spanish language studies from the last 10 years, we will not perform a grey literature search, and we will not carry out a meta-analysis due to the predictable heterogeneity of available studies. Systematic Review registration: This study is registered in Open Science Framework https://bit.ly/2RqKrWp


2009 ◽  
Vol 18 (01) ◽  
pp. 84-95 ◽  
Author(s):  
A. Y. S. Lau ◽  
G. Tsafnat ◽  
V. Sintchenko ◽  
F. Magrabi ◽  
E. Coiera

Summary Objectives To review the recent research literature in clinical decision support systems (CDSS). Methods A review of recent literature was undertaken, focussing on CDSS evaluation, consumers and public health, the impact of translational bioinformatics on CDSS design, and CDSS safety. Results In recent years, researchers have concentrated much less on the development of decision technologies, and have focussed more on the impact of CDSS in the clinical world. Recent work highlights that traditional process measures of CDSS effectiveness, such as document relevance are poor proxy measures for decision outcomes. Measuring the dynamics of decision making, for example via decision velocity, may produce a more accurate picture of effectiveness. Another trend is the broadening of user base for CDSS beyond front line clinicians. Consumers are now a major focus for biomedical informatics, as are public health officials, tasked with detecting and managing disease outbreaks at a health system, rather than individual patient level. Bioinformatics is also changing the nature of CDSS. Apart from personalisation of therapy recommendations, translational bioinformatics is creating new challenges in the interpretation of the meaning of genetic data. Finally, there is much recent interest in the safety and effectiveness of computerised physicianorderentry (CPOE) systems, given that prescribing and administration errors are a significant cause of morbidity and mortality. Of note, there is still much controversy surrounding the contention that poorly designed, implemented or used CDSS may actually lead to harm. Conclusions CDSS research remains an active and evolving area of research, as CDSS penetrate more widely beyond their traditional domain into consumer decision support, and as decisions become more complex, for example by involving sequence level genetic data.


2019 ◽  
Vol 41 (3) ◽  
pp. 552-581 ◽  
Author(s):  
Eduardo Carracedo-Martinez ◽  
Christian Gonzalez-Gonzalez ◽  
Antonio Teixeira-Rodrigues ◽  
Jesus Prego-Dominguez ◽  
Bahi Takkouche ◽  
...  

2010 ◽  
pp. 1056-1070
Author(s):  
Dawn Dowding ◽  
Rebecca Randell ◽  
Natasha Mitchell ◽  
Rebecca Foster ◽  
Valerie Lattimer ◽  
...  

Increasingly, new and extended roles and responsibilities for nurses are being supported through the introduction of clinical decision support systems (CDSS). This chapter provides an overview of research on nurses’ use of CDSS, considers the impact of CDSS on nurse decision making and patient outcomes, and explores the socio-technical factors that impact the use of CDSS. In addition to summarising previous research, both on nurses’ use of CDSS and on use of CDSS more generally, the chapter presents the results of a multi-site case study that explored how CDSS are used by nurses in practice in a range of contexts. The chapter takes a socio-technical approach, exploring the barriers and facilitators to effective CDSS use at a level of the technology itself, the ways people work, and the organisations in which they operate.


Author(s):  
Dawn Dowding ◽  
Rebecca Randell ◽  
Natasha Mitchell ◽  
Rebecca Foster ◽  
Valerie Lattimer ◽  
...  

Increasingly, new and extended roles and responsibilities for nurses are being supported through the introduction of clinical decision support systems (CDSS). This chapter provides an overview of research on nurses’ use of CDSS, considers the impact of CDSS on nurse decision making and patient outcomes, and explores the socio-technical factors that impact the use of CDSS. In addition to summarising previous research, both on nurses’ use of CDSS and on use of CDSS more generally, the chapter presents the results of a multi-site case study that explored how CDSS are used by nurses in practice in a range of contexts. The chapter takes a socio-technical approach, exploring the barriers and facilitators to effective CDSS use at a level of the technology itself, the ways people work, and the organisations in which they operate.


Author(s):  
Taku Harada ◽  
Taiju Miyagami ◽  
Kotaro Kunitomo ◽  
Taro Shimizu

Diagnosis is one of the crucial tasks performed by primary care physicians; however, primary care is at high risk of diagnostic errors due to the characteristics and uncertainties associated with the field. Prevention of diagnostic errors in primary care requires urgent action, and one of the possible methods is the use of health information technology. Its modes such as clinical decision support systems (CDSS) have been demonstrated to improve the quality of care in a variety of medical settings, including hospitals and primary care centers, though its usefulness in the diagnostic domain is still unknown. We conducted a scoping review to confirm the usefulness of the CDSS in the diagnostic domain in primary care and to identify areas that need to be explored. Search terms were chosen to cover the three dimensions of interest: decision support systems, diagnosis, and primary care. A total of 26 studies were included in the review. As a result, we found that the CDSS and reminder tools have significant effects on screening for common chronic diseases; however, the CDSS has not yet been fully validated for the diagnosis of acute and uncommon chronic diseases. Moreover, there were few studies involving non-physicians.


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