Effects of Venesection on Cerebral Function in Chronic Lung Disease

SUMMARY:Regional cerebral blood flow measurements and neuropsychological testing were conducted before and after venesection on 6 patients with polycythemia secondary to chronic obstructive pulmonary disease. Venesection resulted in lowered viscosity and hematocrit, and an accompanying improvement in cerebral perfusion and mental function. Blood flow was significantly increased in the left cerebral hemisphere following phlebotomy, and there was significant improvement in sensory I mental function. Cerebral function would appear to be related to blood flow alterations influenced by the viscosity of the blood.

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Regional Cerebral Blood Flow Measurements Using the 133-Xenon Inhalation Method

Cerebral Blood Flow ◽

10.1007/978-1-4684-5565-6_7 ◽

1988 ◽

pp. 121-143 ◽

Cited By ~ 2

Author(s):

G. Rodriguez ◽

F. De Carli ◽

G. Novellone ◽

S. Marenco ◽

G. Rosadini

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Regional Cerebral Blood Flow ◽

Regional Cerebral Blood ◽

Flow Measurements ◽

Blood Flow Measurements

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Cerebral Vasoreactivity Assessed With Transcranial Doppler and Regional Cerebral Blood Flow Measurements

Stroke ◽

10.1161/01.str.26.12.2302 ◽

1995 ◽

Vol 26 (12) ◽

pp. 2302-2306 ◽

Cited By ~ 56

Author(s):

Arve Dahl ◽

David Russell ◽

Kjell Rootwelt ◽

Rolf Nyberg-Hansen ◽

Emilia Kerty

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Transcranial Doppler ◽

Regional Cerebral Blood Flow ◽

Regional Cerebral Blood ◽

Flow Measurements ◽

Blood Flow Measurements ◽

Cerebral Vasoreactivity

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Improved brain perfusion after electrical cardioversion of atrial fibrillation

EP Europace ◽

10.1093/europace/euz336 ◽

2019 ◽

Vol 22 (4) ◽

pp. 530-537 ◽

Cited By ~ 3

Author(s):

Marianna Gardarsdottir ◽

Sigurdur Sigurdsson ◽

Thor Aspelund ◽

Valdis Anna Gardarsdottir ◽

Lars Forsberg ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Atrial Fibrillation ◽

Blood Flow ◽

Cerebral Blood Flow ◽

Magnetic Resonance ◽

Brain Perfusion ◽

Resonance Imaging ◽

Flow Measurements ◽

Before And After ◽

Blood Flow Measurements

Abstract Aims Atrial fibrillation (AF) has been associated with reduced brain volume, cognitive impairment, and reduced cerebral blood flow. The causes of reduced cerebral blood flow in AF are unknown, but no reduction was seen in individuals without the arrhythmia in a previous study. The aim of this study was to test the hypothesis that brain perfusion, measured with magnetic resonance imaging (MRI), improves after cardioversion of AF to sinus rhythm (SR). Methods and results All patients undergoing elective cardioversion at our institution were invited to participate. A total of 44 individuals were included. Magnetic resonance imaging studies were done before and after cardioversion with both brain perfusion and cerebral blood flow measurements. However, 17 did not complete the second MRI as they had a recurrence of AF during the observation period (recurrent AF group), leaving 17 in the SR group and 10 in the AF group to complete both measurements. Brain perfusion increased after cardioversion to SR by 4.9 mL/100 g/min in the whole brain (P < 0.001) and by 5.6 mL/100 g/min in grey matter (P < 0.001). Cerebral blood flow increased by 58.6 mL/min (P < 0.05). Both brain perfusion and cerebral blood flow remained unchanged when cardioversion was unsuccessful. Conclusion In this study of individuals undergoing elective cardioversion for AF, restoration, and maintenance of SR for at least 10 weeks after was associated with an improvement of brain perfusion and cerebral blood flow measured by both arterial spin labelling and phase contrast MRI. In those individuals where cardioversion was unsuccessful, there was no change in perfusion or blood flow.

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