scholarly journals Prolactin-Secreting Adenomas - Surgical Results

1990 ◽  
Vol 17 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Giulio Maira ◽  
Carmelo Anile ◽  
Laura De Marinis ◽  
Antonino Barbarino
Keyword(s):  
Tumor Recurrence ◽  
Surgical Results ◽  
Total Removal ◽  
Microsurgical Treatment ◽  
Long Term Follow Up ◽  
Grade Ii ◽  
Tumor Regrowth

ABSTRACT:The long-term follow-up of the transsphenoidal microsurgical treatment in 119 consecutively operated women with a PRL-secreting adenoma is presented. An apparent total removal of the tumor was achieved in 98 cases with an enclosed tumor (58 grade I and 40 grade II). In the remaining cases the removal was considered partial. The achievement of persistent normal PRL basal levels was verified in 61 patients (44 grade I and 17 grade II) who had an apparent total removal of the adenoma. In the 37 remaining patients who were thought at surgery to have had total removal we have distinguished two groups: 30 patients showed a “relapse” or “persistence” of PRL levels below 200 ng/ml without clinical and radiological signs of tumor regrowth, and 7 patients with a PRL level higher than 200 ng/ml who had evidence of PRL-secreting tumor recurrence.

Prolactin-Secreting Adenomas: Surgical Results and Long-Term Follow-up

Neurosurgery ◽  
1989 ◽  
Vol 24 (5) ◽  
pp. 736-743 ◽  
Author(s):  
Giulio Maira ◽  
Carmelo Anile ◽  
Laura De Marinis ◽  
Antonino Barbarino
Keyword(s):  
Empty Sella ◽  
Surgical Removal ◽  
Total Removal ◽  
Efficacious Treatment ◽  
Transsphenoidal Microsurgery ◽  
Long Term Follow Up ◽  
Grade Ii ◽  
Adenomatous Tissue

ABSTRACT Transsphenoidal surgery is an efficacious treatment for patients with prolactin (PRL)-secreting adenomas, even if disrupted pituitary-hypothalamic relationships may persist and/or a recurrence of the PRL-secreting tumor can occur. In this paper, we analyze the long-term follow-up of 119 consecutively treated women who underwent transsphenoidal microsurgery for PRL-secreting adenomas. Apparent total removal of the tumor was achieved in 98 patients who had enclosed tumors (58 with Grade-I tumors and 40 with Grade II). In the remaining patients, the removal was considered partial. Persistent normal basal PRL levels were achieved in 61 patients who had apparent total removal of the adenoma (44 with Grade I tumors and 17 with Grade II). Of the remaining 37 patients in whom surgical removal of the adenomatous tissue was thought to be total, 30 had persistent nonevolutive, high PRL levels ranging from 21 to 196 ng/ml, without clinical and radiological signs of tumor regrowth, and 7 with PRL levels ranging from 56 to 560 ng/ml had a recurrence of the PRL-secreting tumor. These data seem to indicate that a slightly elevated postsurgical PRL value does not imply that tumoral tissue is still present. Nontumoral conditions (i.e., a secondary empty sella) could induce functional hyperprolactinemia.

scholarly journals The cerebellar peduncle as localization of a recurrent atypical plexus papilloma: A case report

2019 ◽  
Vol 10 ◽  
pp. 65
Author(s):  
Christian Saleh ◽  
Stefanie Wilmes ◽  
Kristine Ann Blackham ◽  
Dominik Cordier ◽  
Kerstin Hug ◽  
...  
Keyword(s):  
Fourth Ventricle ◽  
Tumor Recurrence ◽  
Middle Cerebellar Peduncle ◽  
Long Term Follow Up ◽  
History Of ◽  
Cerebellar Peduncle ◽  
Left Middle ◽  
Plexus Papilloma

Background: Choroid plexus papillomas (CPPs) are infrequently encountered brain tumors with the majority originating in the ventricular system. Rarely, CPP occurs outside of the ventricles. Case Description: We report the case of a recurrent CPP that initially originated within the fourth ventricle, though years later it recurred in the left middle cerebellar peduncle. Conclusion: Patients with cerebellar plexus papilloma need long-term follow-up comprising regular magnetic resonance imagings since, in patients with a history of CPP, any new mild symptomatology, even years after the initial presentation, may be an early sign of tumor recurrence.

Pancreaticoduodenectomy for distal cholangiocarcinoma: surgical results, prognostic factors, and long-term follow-up

2015 ◽  
Vol 400 (5) ◽  
pp. 623-628 ◽  
Author(s):  
Stefano Andrianello ◽  
Salvatore Paiella ◽  
Valentina Allegrini ◽  
Marco Ramera ◽  
Alessandra Pulvirenti ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Surgical Results ◽  
Distal Cholangiocarcinoma ◽  
Long Term Follow Up

Repair of double-chambered right ventricle: surgical results and long-term follow-up

2001 ◽  
Vol 72 (5) ◽  
pp. 1520-1522 ◽  
Author(s):  
Yoshikazu Hachiro ◽  
Nobuyuki Takagi ◽  
Tetsuya Koyanagi ◽  
Masayuki Morikawa ◽  
Tomio Abe
Keyword(s):  
Right Ventricle ◽  
Surgical Results ◽  
Long Term Follow Up

Surgical Results for Chronic Empyema Using Omental Pedicled Flap: Long-Term Follow-Up Study

2005 ◽  
Vol 79 (6) ◽  
pp. 1857-1861 ◽  
Author(s):  
Yoshitomo Okumura ◽  
Shin-ichi Takeda ◽  
Hiroki Asada ◽  
Masayoshi Inoue ◽  
Noriyoshi Sawabata ◽  
...  
Keyword(s):  
Pedicled Flap ◽  
Surgical Results ◽  
Follow Up Study ◽  
Chronic Empyema ◽  
Long Term Follow Up

Microsurgical Treatment for Complex Basilar Artery Aneurysms with Long-Term Follow-Up in a Series of 35 Cases

2018 ◽  
Vol 111 ◽  
pp. e710-e721 ◽  
Author(s):  
Yaoling Liu ◽  
Xiangen Shi ◽  
K I Singh KC ◽  
Yuming Sun ◽  
Fangjun Liu ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Microsurgical Treatment ◽  
Long Term Follow Up

scholarly journals The applicability of established clinical and histopathological risk factors for tumor recurrence during long-term postoperative care in meningioma patients

2021 ◽  
Author(s):  
Swenja Lüthge ◽  
Dorothee Cäcilia Spille ◽  
Andrea Ulrike Steinbicker ◽  
Stephanie Schipmann ◽  
Eileen Maria Susanne Streckert ◽  
...  
Keyword(s):  
Risk Factors ◽  
Skull Base ◽  
Tumor Recurrence ◽  
Skull Base Tumor ◽  
High Grade ◽  
Entire Cohort ◽  
Long Term Follow Up ◽  
Base Location

Abstract Risk factors to predict late-onset tumor recurrence in meningioma patients are urgently needed to schedule control intervals during long-term follow-up. We therefore analyzed the value of established risk factors for postoperative meningioma recurrence for the prediction of long-term prognosis. Correlations of clinical and histopathological variables with tumor relapse after 3, 5, and 10 years following microsurgery were analyzed in uni- and multivariate analyses, and compared to findings in the entire cohort. In the entire cohort (N = 1218), skull base location (HR: 1.51, 95%CI 1.05–2.16; p = .026), Simpson ≥ IV resections (HR: 2.41, 95%CI 1.52–3.84; p < .001), high-grade histology (HR: 3.70, 95%CI 2.50–5.47; p < .001), and male gender (HR: 1.46, 95%CI 1.01–2.11; p = .042) were independent risk factors for recurrence. Skull base location (HR: 1.92, 95%CI 1.17–3.17; p = .010 and HR: 2.02, 95%CI 1.04–3.95; p = .038) and high-grade histology (HR: 1.87, 95%CI 1.04–3.38; p = .038 and HR: 2.29, 95%CI 1.07–4.01; p = .034) but not subtotal resection (HR: 1.53, 95%CI .68–3.45; p = .303 and HR: 1.75, 95%CI .52–5.96; p = .369) remained correlated with recurrence after a recurrence-free follow-up of ≥ 3 and ≥ 5 years, respectively. Postoperative tumor volume was related with recurrence in general (p < .001) but not beyond a follow-up of ≥ 3 years (p > .05). In 147 patients with a follow-up of ≥ 10 years, ten recurrences occurred and were not correlated with any of the analyzed variables. Skull base tumor location and high-grade histology but not the extent of resection should be considered when scheduling the long-term follow-up after meningioma surgery. Recurrences ≥ 10 years after surgery are rare, and predictors are lacking.

The Importance of Long-Term Follow-up after Endoscopic Pituitary Surgery: Durability of Results and Tumor Recurrence

2020 ◽  
Author(s):  
Joao Paulo Almeida ◽  
Hirokazu Takami ◽  
Raha Tabasinejad ◽  
Miguel Marigil Sanchez ◽  
Carlos Velasquez ◽  
...  
Keyword(s):  
Tumor Recurrence ◽  
Pituitary Surgery ◽  
Long Term Follow Up
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