A Banded Structure in Human Connective Tissue

Author(s):  
C. N. Sun ◽  
H. J. White

The occurrence of the extracellular, banded or cross-striated material has been reported in many types of tissues. It generally appears as scattered fusiform strands showing cross-banding with a periodicity of 1000 to 1500 Å as well as delicate longitudinally oriented elements. Such a banded structure (BS) first noted by Luse in a neural tumor, was confirmed by others. Similar structures have more recently been found in a variety of organs both human and animal. In our own experience they were seen in a hyperplastic parathyroid gland, follicular adenoma of thyroid gland, sarcoidosis of lymph node and in non-specific demyelinization of nerves. We should add that to our knowledge, BS has not been previously reported in the parathyroid gland or thyroid gland.

2015 ◽  
Vol 120 (2) ◽  
Author(s):  
Henry Johansson

The discovery of the parathyroid gland by the Uppsala anatomist Ivar Sandström (Figure 1) is often called the last anatomical discovery. That remarkable discovery was made in 1877 at the Anatomical Department in Uppsala. At that time Sandström was a young medical student, who had worked as an assistant at the department since 1873. His discovery was published in Upsala Läkareförenings Förhandlingar, in 1880 (1). His publication was in Swedish, and the paper was entitled ‘On a New Gland in Man and Several Animals’. The article comprised 30 pages, and in the introduction Sandström writes: Almost three years ago I found on the thyroid gland of a dog a small organ, hardly as big as a hemp seed, which was enclosed in the same connective tissue as the thyroid, but could be distinguished therefrom by the light colour


2007 ◽  
Vol 6 (2) ◽  
pp. 98-102
Author(s):  
D. I. Malinin ◽  
V. G. Petrov

The aim of the study was to improve surgical results of patients having thyroid gland pathology by the development of the surgery method directed to increasing possibility of injury and maintenance of the upper laryngeal nerve integrity. Method of performing extrafascial hemithyreoidectomy with visualization of recurrent nerve, parathyroid gland and upper thyroid artery is presented which is directed to decrease specific complications (vocal fold paresis, hypoparathyreosis) and complications associated with the upper laryngeal nerve injury. Using this method, 166 patients having node pathology of thyroid gland were operated on. This method resulted in decreased number of complications (from 15,0 to 2,6%).


2020 ◽  
Vol 26 (4) ◽  
pp. 43-48
Author(s):  
Vasilisa Yurievna Rayn ◽  
◽  
Mikhail Alexandrovich Persidsky ◽  
Dmitry Alexandrovich Mizev ◽  
Zakhar Albertovich Kashbulin ◽  
...  

A typical clinical presentation of a thyroid follicular adenoma is illustrated with a real patient’s history, labs, neck MRI and morphology using modern guidelines on the topic. The article is structured using case-based approach.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Sun Hye Jeong ◽  
Hyun Sook Hong ◽  
Eun Hye Lee ◽  
Jeong Ja Kwak

Objectives. We compared the ultrasonography and pathology features of papillary thyroid carcinoma (PTC) in pediatric and adolescents with Hashimoto’s thyroiditis (HT) with those of non-HT patients.Materials and Methods. Eleven patients who were surgically confirmed to have pediatric or adolescent PTC from 2006 to 2014 were included in this study. We retrospectively analyzed the preoperative ultrasonography and pathology features of PTC arising in HT and non-HT patients.Results. On ultrasonography, thyroid gland was lobulated and enlarged, with many scattered microcalcifications in four of five HT patients. Four of six non-HT patients had suspicious masses with calcifications. The diffuse sclerosing variant of PTC (DSVPTC) was found in three of five HT patients, but none in non-HT patients. Macroscopic or microscopic extrathyroidal extension was evident in all of the HT patients and four of the non-HT patients. Neck lymph node metastases were in all HT patients and five of non-HT patients.Conclusions. Three of five PTCs in pediatric and adolescent HT patients were DSVPTC, whereas all PTCs of the non-HT patients were classic type. On ultrasonography, thyroid gland was diffusely enlarged with scattered microcalcifications in four of five HT patients. All five HT cases had aggressive disease, including extrathyroidal extension and cervical lymph node metastases.


2016 ◽  
Vol 6 (12) ◽  
pp. 985-989
Author(s):  
R Pathak ◽  
KBR Prasad ◽  
SK Rauniyar ◽  
S Pudasaini ◽  
K Pande ◽  
...  

Background: Fine needle aspiration cytology is a minimally invasive technique used in the initial diagnosis of different types of lesions located in head and neck region commonly originating from cervical lymph node, thyroid gland, salivary glands and soft tissues. The objective of this study was to evaluate the diagnostic accuracy, sensitivity and speci city of FNAC in various head and neck lesions in correlation with their histopathological examination. Materials and methods: A hospital based prospective study was conducted among 209 patients with palpable head and neck region swellings in the Department of Pathology, Bhaktapur Cancer Hospital and the Department of Pathology, Nepal Medical College from August 2014 to July 2015. FNAC were done from palpable masses of head and neck regions. Data entry and analysis were done using SPSS 17. Result: There were 209 FNAC cases enrolled, out of which lymph node lesions (n=128) were the most common lesions followed by thyroid (n=40), other soft tissues (n=27) and salivary gland (n=14). Reactive lymph nodes, colloid goiter, epidermoid cyst and sialadenosis were the predominant diagnosis of lymph nodes, thyroid gland, soft tissues and salivary gland respectively. Highest accuracy, sensitivity and speci city were observed in thyroid gland, salivary gland and soft tissues. However, four false negative results for malignancy were reported in lymph node lesions. Conclusion: Head and neck region swellings are the commonly encountered conditions. FNAC being highly accurate, sensitive and speci c makes it useful and reliable procedure for screening and diagnosis of palpable masses in head and neck region. 


2008 ◽  
Vol 132 (4) ◽  
pp. 622-632
Author(s):  
William C. Faquin

Abstract Nodules of the thyroid gland are frequently encountered, occurring in up to 7% of the population, and although most of these nodules are benign, carcinomas of the thyroid gland are the most common malignancy of the endocrine system. Although the different types of thyroid carcinoma are few, a wide variety of recurring problems exists in both their histologic and cytologic evaluation. Here, I will review a selected group of problematic areas, including unusual histologic variants of follicular adenoma, criteria for diagnosing minimally invasive follicular carcinoma, the use of fine-needle aspiration as a screening test for follicular neoplasia, challenging variants of papillary carcinoma, and features of poorly differentiated carcinoma.


2005 ◽  
Vol 26 (5) ◽  
pp. 348-350 ◽  
Author(s):  
William J. Kim ◽  
Raphaelle Souillard ◽  
Margaret S. Brandwein ◽  
William Lawson ◽  
Peter M. Som

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S41-S42
Author(s):  
Joanna Solarewicz ◽  
Vijaya Reddy ◽  
Pincas Bitterman ◽  
Ritu Ghai ◽  
Paolo Gattuso

Abstract Objectives Lipomatous metaplasia involving the thyroid gland is uncommon in surgical pathology and the majority of published literature is confined to single case reports. We undertook a retrospective study to assess the frequency of fat metaplasia among benign and neoplastic thyroid lesions. Methods Surgical pathology files from 1992 to 2018 at our institution were searched for lipomatous metaplasia involving the thyroid gland. A total of 2,018 cases of thyroid lesions after lobectomy or total thyroidectomy with or without regional lymph node sampling were identified. Patient clinical and pathologic data were reviewed. Results The 2,018 thyroid cases reviewed included 828 papillary carcinomas, 33 medullary carcinomas, 26 anaplastic carcinomas, 25 follicular carcinomas, 262 follicular adenomas, 422 goiters, 373 Hashimoto thyroiditis, and 49 Grave disease. Lipomatous metaplasia was recorded in 17 cases (0.8%), which included 8 males and 9 females with a mean age of 67 years (range: 55 to 82). The most common lesion containing fat metaplasia was goiter (7/422 cases, 1.7%), followed by follicular adenoma (4/262, 1.5%), papillary carcinoma (4/828, 0.5%), Hashimoto thyroiditis (1/373, 0.3%), and Grave disease (1/49, 2%). When associated with papillary carcinoma, lipomatous metaplasia was located in the surrounding benign thyroid tissue in 2/4 cases and in malignant papillary structures metastatic to neck lymph nodes in the remaining 2/4 cases. Conclusion Lipomatous metaplasia of the thyroid gland is a rare phenomenon, present in only 17/2,018 cases (0.8%) in our study. It was more commonly seen in reactive processes (9/844 cases, 1.1%) and follicular adenomas (4/262 cases, 1.5%). Among the 912 cases of malignant tumors, fat metaplasia was only identified in papillary carcinoma (4/828, 0.5%), half of which showed metaplasia at the metastatic site. The presence of lipomatous metaplasia in reactive as well as neoplastic lesions cannot be used as a reliable histologic feature to exclude a neoplastic process.


Sign in / Sign up

Export Citation Format

Share Document