Differentiation of Skin Lesions in Acute Myeloid Leukemia by Myeloperoxidase Cytochemistry

Skin lesions are common in acute myeloid leukemia (AML) and occasionally are the presenting symptom. Usually these lesions are nonspecific, i.e. due to hemorrhage, infection, anemia, drug sensitivity or to corticosteroid therapy. Specific leukemic lesions are due to infiltration of the skin by myeloblasts or immature neutrophil series cells and can be complicated by infection.Rapid identification of the type of lesion can be very important for if it is due to sepsis it may require immediate treatment by antibiotics or antiviral agents. If it is a specific lesion (leukemia cutis of AML) due to infiltration by myeloblasts, it may require a change in chemotherapy or adjunctive X-radiation or electron beam therapy.

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Prediction of the duration of complete remission in acute myeloid leukemia by in vitro drug sensitivity assay

Leukemia Research ◽

10.1016/0145-2126(86)90173-6 ◽

1986 ◽

Vol 10 (1) ◽

pp. 107

Author(s):

J.P. Marie ◽

R Zittoun ◽

D Thevenin

Keyword(s):

Acute Myeloid Leukemia ◽

Complete Remission ◽

Myeloid Leukemia ◽

Drug Sensitivity ◽

Drug Sensitivity Assay ◽

Acute Myeloid

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Invasive aspergillosis with disseminated skin ınvolvement in a patient with acute myeloid leukemia: a rare case

Hematology Reports ◽

10.4081/hr.2017.6997 ◽

2017 ◽

Vol 9 (2) ◽

Cited By ~ 1

Author(s):

Duygu Mert ◽

Gülşen Iskender ◽

Fazilet Duygu ◽

Alparslan Merdin ◽

Mehmet Sinan Dal ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Invasive Aspergillosis ◽

Myeloid Leukemia ◽

Rare Case ◽

Invasive Pulmonary Aspergillosis ◽

Skin Lesions ◽

Immunocompromised Patients ◽

Skin Involvement ◽

Pulmonary Aspergillosis ◽

Acute Myeloid

Invasive pulmonary aspergillosis is most commonly seen in immunocompromised patients. Besides, skin lesions may also develop due to invasive aspergillosis in those patients. A 49-year-old male patient was diagnosed with acute myeloid leukemia. The patient developed bullous and zosteriform lesions on the skin after the 21st day of hospitalization. The skin biopsy showed hyphae. Disseminated skin aspergillosis was diagnosed to the patient. Voricanazole treatment was initiated. The patient was discharged once the lesions started to disappear.

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Leukemia Cutis in a 32-Year-Old Male with Acute Myeloid Leukemia

Journal of Enam Medical College ◽

10.3329/jemc.v9i2.41416 ◽

2019 ◽

Vol 9 (2) ◽

pp. 133-135

Author(s):

Meher Afsun ◽

Rokon Uddin ◽

Md Abu Baker ◽

Iftekhar Ahmed

Keyword(s):

Acute Myeloid Leukemia ◽

Male Patient ◽

Myeloid Leukemia ◽

Clinical Presentation ◽

Systemic Disease ◽

Cutaneous Manifestation ◽

Cutaneous Lesions ◽

Initial Manifestation ◽

Leukemia Cutis ◽

Acute Myeloid

Leukemia cutis (LC) is a rare cutaneous manifestation of leukemia. Clinical presentation of the disease differs among patients depending on types. LC can precede, follow, occur simultaneously with, or present in the absence of the systemic leukemia. Leukemic involvement of the skin may appear as initial manifestation of recurrence or dissemination of systemic disease. Here we report a case of a 32-year-old male patient known to have acute myeloid leukemia with multiple cutaneous lesions diagnosed as LC. J Enam Med Col 2019; 9(2): 133-135

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