scholarly journals Invasive aspergillosis with disseminated skin ınvolvement in a patient with acute myeloid leukemia: a rare case

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
Duygu Mert ◽  
Gülşen Iskender ◽  
Fazilet Duygu ◽  
Alparslan Merdin ◽  
Mehmet Sinan Dal ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Invasive Aspergillosis ◽  
Myeloid Leukemia ◽  
Rare Case ◽  
Invasive Pulmonary Aspergillosis ◽  
Skin Lesions ◽  
Immunocompromised Patients ◽  
Skin Involvement ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

Invasive pulmonary aspergillosis is most commonly seen in immunocompromised patients. Besides, skin lesions may also develop due to invasive aspergillosis in those patients. A 49-year-old male patient was diagnosed with acute myeloid leukemia. The patient developed bullous and zosteriform lesions on the skin after the 21st day of hospitalization. The skin biopsy showed hyphae. Disseminated skin aspergillosis was diagnosed to the patient. Voricanazole treatment was initiated. The patient was discharged once the lesions started to disappear.

Thoracoscopic Lingulectomy for Invasive Pulmonary Aspergillosis

2007 ◽  
Vol 73 (3) ◽  
pp. 279-280 ◽  
Author(s):  
Bryan A. Whitson ◽  
Michael A. Maddaus ◽  
Rafael S. Andrade
Keyword(s):  
Acute Myeloid Leukemia ◽  
Mortality Rate ◽  
Myeloid Leukemia ◽  
Immunocompromised Patient ◽  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Immunocompromised Patients ◽  
Anatomic Resection ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

Invasive pulmonary aspergillosis (IPA) is associated with a high mortality rate in immunocompromised patients. Surgery has a therapeutic role for selected patients when the main objective is to achieve infection control with minimal lung resection. Large or deep-seated lesions may require an anatomic resection such as segmentectomy, lobectomy, or pneumonectomy. Thoracoscopic lobectomy has been described as a treatment of localized IPA; however, thoracoscopic anatomic segmentectomy has not been reported until now. Herein, we describe a case of thoracoscopic lingulectomy for localized IPA in an immunocompromised patient: this operation minimized the delay in resuming therapy for the patient's underlying acute myeloid leukemia. Video-assisted thoracoscopic segmentectomy can be safely performed for localized IPA.

scholarly journals Fatal Invasive Pulmonary Aspergillosis in COVID-19 Patient with Acute Myeloid Leukemia in Iran

2020 ◽  
Vol 185 (6) ◽  
pp. 1077-1084
Author(s):  
Elahe Nasri ◽  
Parisa Shoaei ◽  
Bahareh Vakili ◽  
Hossein Mirhendi ◽  
Somayeh Sadeghi ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

scholarly journals Successful treatment of Pseudomembranous necrotizing Aspergillus tracheobronchitis in a patient with acute myeloid leukemia

2014 ◽  
Vol 142 (7-8) ◽  
pp. 488-491 ◽  
Author(s):  
Jelena Stanic ◽  
Zivka Eri ◽  
Aleksandar Tepavac ◽  
Tatjana Djeric ◽  
Bojan Zaric ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Immunocompromised Patients ◽  
Shortness Of Breath ◽  
Rare Form ◽  
Pulmonary Aspergillosis ◽  
Inspiratory Stridor ◽  
Chest Ct Scan ◽  
Acute Myeloid

Introduction. Pseudomembranous necrotizing Aspergillus tracheobronchitis is a rare form of pulmonary aspergillosis which occurs in immunocompromised patients. Case Outline. A female patient aged 71, suffering from acute myeloid leukemia, developed the symptoms of progressive shortness of breath and inspiratory stridor. The diagnosis in our case was made on the histological findings from tissues obtained by bronchoscopy. A chest CT scan suggested the state of the compromised trachea and left principal bronchus lumen. The long-term regimen with itraconazole in the dose of 400 mg/24 hours proved efficient in our patient. Conclusion. Progressive shortness of breath and inspiratory stridor in immunocompromised patients along with radiological and CT changes should be also considered as pulmonary aspergillosis in differential diagnosis.

scholarly journals THE EFFICACY OF POSACONAZOLE FOR PROPHYLAXIS OF INVASIVE MYCOSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

2017 ◽  
pp. 118-124
Author(s):  
G. A. Klyasova ◽  
V. A. Okhmat ◽  
E. N. Parovichnikova ◽  
E. O. Gribanova ◽  
V. V. Troitskaya ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Median Duration ◽  
Myeloid Leukemia ◽  
De Novo ◽  
Invasive Pulmonary Aspergillosis ◽  
Chemotherapy Cycle ◽  
Pulmonary Aspergillosis ◽  
Invasive Mycoses ◽  
De Novo Aml ◽  
Acute Myeloid

Efficacy of posaconazole for prophylaxis was evaluated in 77 chemotherapy cycles in 59 patients with acute myeloid leukemia (AML) aged 39 (17–62) years from 2012  till 2017. Posaconazole was given in oral suspension 200 mg three times a day after meal during chemotherapy cycle or on 1st  day after the cycle. Administration of posaconazole predominated in patients with de novo AML (84.5%) on 1st induction cycles (66.3%). Neutropenia was present in all patients with median duration of 22 days. Median duration of prophylaxis was 21  (2–57)  days. Posaconazole prophylaxis was interrupted in 28  (36.4%) of 77 cases, mainly due to diarrhea (28.6%). In 17 (61%) of 28 cases prophylaxis was resumed within a median of 3 days. In 72 (93.5%) of cases duration of posaconazole prophylaxis was ≥ 7 days, in 5 (6.5%) cases < 7 days. Efficacy of prophylaxis was evaluated in cases of posaconazole duration ≥ 7 days. Invasive pulmonary aspergillosis (probable) was in 2 (2.7%) of 72 cases. Administration of posaconazole with duration ≥ 7 days was in 46 cases on chemotherapy cycle, in 26 cases – on first day after the cycle. Patients using Posaconazole after a course of chemotherapy in comparison with patients receiving the drug in the first days of the course had significantly less interruptions of prophylaxis (11,5% vs 41,3%, p=0.009) and a reduction in duration of Posaconazole using (19 days vs 27 days, p=0.007).One case of invasive aspergillosis was registered in each group.We confirmed the  efficacy of posaconazole  for prophylaxis of invasive mycoses  in patients  with AML. Administration of posaconazole prophylaxis on first day after the end of chemotherapy cycle results in saving of drug by reducing duration of posaconazole using by 8 days and does not increase the incidence of invasive mycoses.

Baseline Chest Computed Tomography for Early Diagnosis of Invasive Pulmonary Aspergillosis in Hemato-oncological Patients: A Prospective Cohort Study

2019 ◽  
Vol 69 (10) ◽  
pp. 1805-1808 ◽  
Author(s):  
Roni Bitterman ◽  
Emilia Hardak ◽  
Marina Raines ◽  
Anat Stern ◽  
Tzila Zuckerman ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Acute Myeloid Leukemia ◽  
Early Diagnosis ◽  
Myeloid Leukemia ◽  
Invasive Pulmonary Aspergillosis ◽  
Newly Diagnosed ◽  
Pulmonary Aspergillosis ◽  
Chest Computed Tomography ◽  
Oncological Patients ◽  
Acute Myeloid

Abstract Invasive pulmonary aspergillosis (IPA) has dire consequences in hemato-oncological patients. We report our experience with performing routine baseline chest computed tomography for early diagnosis of IPA. We found high rates of proven or probable IPA diagnosed on admission among patients with newly diagnosed acute myeloid leukemia.

scholarly journals Invasive Pulmonary Aspergillosis after Recent Influenza in a Child with Acute Myeloid Leukemia

2015 ◽  
Vol 22 (2) ◽  
pp. 190-194
Author(s):  
Beom-Joon Kim ◽  
Seong koo Kim ◽  
Seung Beom Han ◽  
Jae Wook Lee ◽  
Jong-Seo Yoon ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

scholarly journals A rare case of acute myeloid leukemia with der(1)t(1;19)(p13;p13.1)

2019 ◽  
Vol 12 ◽  
pp. 100175
Author(s):  
Meghan McAlice ◽  
Munaza Gohar ◽  
Ahmed Alshaban ◽  
Attilio Orazi ◽  
Vijay Tonk ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Rare Case ◽  
Acute Myeloid
Sign in / Sign up

Export Citation Format

Share Document