Does milk fortification increase the risk of necrotising enterocolitis in preterm infants with congenital heart disease?

2012 ◽  
Vol 23 (3) ◽  
pp. 450-453 ◽  
Author(s):  
Atul Malhotra ◽  
Alex Veldman ◽  
Samuel Menahem

AbstractPrematurity and low birth weight adds to the risk of serious congenital heart disease in infants. It may also delay surgical intervention, especially when cardiopulmonary bypass is required, or where an aortopulmonary shunt is necessary to maintain adequate oxygenation. In this setting, neonatologists are faced with the challenge of accelerating the infant's growth to allow for early surgery. We describe the cases of two infants in whom an attempt to fortify the feeds was associated with necrotising enterocolitis, with a lethal outcome in one. The outcome suggests caution in fortifying feeds in premature infants with serious congenital heart disease.

1994 ◽  
Vol 107 (2) ◽  
pp. 562-568 ◽  
Author(s):  
Sophronia O. Turner-Gomes ◽  
Lesley Mitchell ◽  
W.G. Williams ◽  
Maureen Andrew

Children ◽  
2020 ◽  
Vol 7 (9) ◽  
pp. 113
Author(s):  
Ranjit I. Kylat

The incidence of congenital lobar overinflation (CLO) is reported at 1 in 20,000–30,000 live births and represents 10% of all congenital lung malformations. The occurrence of concomitant congenital heart disease (CHD) and CLO ranges from 12% to 20%. There are diverging views in the management as to whether early lobectomy or repair of the cardiac defect, with the assumption that respiratory symptomatology would gradually resolve, or a combined lung and cardiac repair would be the ideal first step in the management. In concomitant CLO and CHD, the surgical decision has to be individualized. Prior to surgical intervention a thorough evaluation may be needed with contrast computed tomography (CT) or magnetic resonance imaging (MRI), bronchoscopy, and if needed cardiac catheterization. CLO improves with management of many left to right shunts and in those with anomalous vessels, but early lobectomy or combined approach may be considered in those symptomatic patients with more complex CHD.


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