Remember to Buy Milk on the Way Home! A Meta-analytic Review of Prospective Memory in Mild Cognitive Impairment and Dementia

2012 ◽  
Vol 18 (4) ◽  
pp. 706-716 ◽  
Author(s):  
Esther van den Berg ◽  
Neeltje Kant ◽  
Albert Postma
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Literature Search ◽  
Case Control ◽  
Retrospective Memory ◽  
Case Control Studies ◽  
Cognitive Correlates ◽  
Analytic Review ◽  
Event Based

AbstractProspective memory (PM) is the ability to remember to execute delayed intentions. Previous studies indicate that PM is impaired in persons with mild cognitive impairment (MCI) and dementia, but the extent, nature, and cognitive correlates are unclear. A meta-analytic review was, therefore, performed (literature search 1990 to July 2011) on case-control studies on PM in dementia (10 studies, 336 patients, 505 controls) and MCI (7 studies, 225 patients, 253 controls). Differences between event-based and time-based PM and between measures of prospective and retrospective memory were examined, as well as correlations with other cognitive functions. Results showed that patients with dementia or MCI exhibit large deficits in PM (Hedges’ d −1.62 [95% confidence interval −1.98 to −1.27; p < .0001] for dementia; −1.24 [−1.51 to −0.995; p < .0001] for MCI; difference dementia vs. MCI: QM = 1.94, p = .16). Impairments were comparable in size for event-based and time-based PM (p > .05), as well as for prospective and retrospective memory (p > .05). PM showed modest correlations with measures of retrospective memory (median r = 0.27) and executive functioning (median r = 0.30). PM appears a valid construct in neuropsychological assessment in patients with dementia or MCI, but more insight is needed in the optimal characteristics of PM tasks to be used in clinical practice. (JINS, 2012, 18, 1–11)

Prospective memory in amnestic mild cognitive impairment

2009 ◽  
Vol 15 (3) ◽  
pp. 407-415 ◽  
Author(s):  
STELLA KARANTZOULIS ◽  
ANGELA K. TROYER ◽  
JILL B. RICH
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Amnestic Mild Cognitive Impairment ◽  
Attention Switching ◽  
Memory For Intentions ◽  
Neuropsychological Evaluations ◽  
Event Based ◽  
Cue Detection ◽  
Error Types

AbstractIndividuals with amnestic mild cognitive impairment (aMCI) often complain of difficulty remembering to carry out intended actions, consistent with findings of impaired prospective memory (PM) in this population. In this study, individuals with aMCI (N = 27) performed worse than healthy controls (N = 27) on the Memory for Intentions Screening Test (Raskin, 2004), including on time- and event-based subscales, and recognition of the intentions. The aMCI participants made more errors overall, but the proportion of the various error types did not differ between the two groups. Across all error types, both groups made more retrospective than prospective errors, especially on event-based PM tasks. Overall, the findings suggest that PM impairment in aMCI is associated with deficient cue detection involving both automatic (as in event-based tasks) and more strategic detection (as in time-based tasks) processes. These difficulties are likely due to a combination of problematic retrospective episodic memory (e.g., reduced encoding and/or consolidation of cue–intention pairings) and executive functions (e.g., decreased self-initiation, attention switching, and/or inhibition on memory tasks). Formal assessment of PM may help characterize the nature of the memory impairment among individuals with aMCI in clinical neuropsychological evaluations. (JINS, 2009, 15, 407–415.)

Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer’s disease etiology using a novel event-based prospective memory task

2009 ◽  
Vol 15 (1) ◽  
pp. 154-159 ◽  
Author(s):  
ALBERTO BLANCO-CAMPAL ◽  
ROBERT F. COEN ◽  
BRIAN A. LAWLOR ◽  
JOSEPH B. WALSH ◽  
TERESA E. BURKE
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Small Sample ◽  
Cutoff Score ◽  
Convenience Sample ◽  
Disease Etiology ◽  
Event Based

AbstractWe investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely used retrospective memory (RM) tests (Rivermead Paragraph Recall Test and CERAD-Word List Test), when detecting mild cognitive impairment of suspected Alzheimer’s disease etiology (MCI-AD) (N = 19) from normal controls (NC) (N = 21). Statistical analyses showed high discriminatory capacity of the PM task for detecting MCI-AD. The Non-Specific-Non-Salient condition proved particularly useful in detecting MCI-AD, possibly reflecting the difficulty of the task, requiring more strategic attentional resources to monitor for the PM cue. With a cutoff score of <4/10, the Non-Specific-Non-Salient condition achieved a sensitivity = 84%, and a specificity = 95%, superior to the most discriminative RM test used (CERAD-Total Learning: sensitivity = 83%; specificity = 76%). Results suggest that PM is an early sign of memory failure in MCI-AD and may be a more pronounced deficit than retrospective failure, probably reflecting the greater self-initiated retrieval demands involved in the PM task used. Limitations include the relatively small sample size, and the use of a convenience sample (i.e. memory clinic attenders and healthy active volunteers), reducing the generalizability of the results, which should be regarded as preliminary. (JINS, 2009, 15, 154–159.)

Clinical Measures of Prospective Memory in Amnestic Mild Cognitive Impairment

2012 ◽  
Vol 18 (2) ◽  
pp. 295-304 ◽  
Author(s):  
Jacinta Delprado ◽  
Glynda Kinsella ◽  
Ben Ong ◽  
Kerryn Pike ◽  
David Ames ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Prospective Memory ◽  
Amnestic Mild Cognitive Impairment ◽  
Retrospective Memory ◽  
Single Trial ◽  
Discriminative Ability ◽  
Healthy Older Adults ◽  
Event Based ◽  
Complex Attention

AbstractRecent research has established that individuals with amnestic mild cognitive impairment (aMCI) have impaired prospective memory (PM); however, findings regarding differential deficits on time-based versus event-based PM have been less clear. Furthermore, the diagnostic utility of PM measures has received scant attention. Healthy older adults (n = 84) and individuals with aMCI (n = 84) were compared on the Cambridge Prospective Memory Test (CAMPROMPT) and two single-trial event-based PM tasks. The aMCI participants showed global impairment on all PM measures. Measures of retrospective memory and complex attention predicted both time and event PM performance for the aMCI group. Each of the PM measures was useful for discriminating aMCI from healthy older adults and the time- and event-based scales of the CAMPROMPT were equivalent in their discriminative ability. Surprisingly, the brief PM tasks were as good as more comprehensive measures of PM (CAMPROMPT) at predicting aMCI. Results indicate that single-trial PM measures, easily integrated into clinical practice, may be useful screening tools for identifying aMCI. As PM requires retrospective memory skills along with complex attention and executive skills, the interaction between these skills may explain the global PM deficits in aMCI and the good discriminative ability of PM for diagnosing aMCI. (JINS, 2012, 18, 295–304)

scholarly journals Prospective and Retrospective Memory Complaints in Mild Cognitive Impairment and Mild Alzheimer's Disease

2009 ◽  
Vol 10 (1) ◽  
pp. 59-75 ◽  
Author(s):  
Anne Eschen ◽  
Mike Martin ◽  
Ursula Schreiter Gasser ◽  
Matthias Kliegel
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Executive Functions ◽  
Prospective Memory ◽  
Cognitive Abilities ◽  
Retrospective Memory ◽  
Healthy Older Adults ◽  
Memory Complaints

AbstractCurrent management attempts for Alzheimer's disease (AD) focus on the identification of individuals in the preclinical stage. This has led to the development of the diagnostic concept of Mild Cognitive Impairment (MCI), which applies to individuals with declining cognitive abilities but largely preserved everyday functioning. Previous findings indicate that prospective memory deficits are a sensitive marker of preclinical AD and that awareness of prospective memory failures is particularly high, based on its dependence on executive functions. Thus, the goal of this study was to evaluate the usefulness of subjective prospective versus retrospective memory complaints for an initial screening for MCI and their respective associations with executive functions. 71 healthy older adults, 27 MCI patients, and 9 patients with mild AD completed the Prospective and Retrospective Memory Questionnaire (PRMQ) and three executive functions tests. The healthy and the MCI group could not be distinguished by their level of subjective prospective or retrospective memory complaints, but the mild AD patients differed from the other groups by complaining more about retrospective than prospective memory failures. For the healthy older adults, the prospective memory complaints were correlated to an inhibition test, whereas they did not correlate with any of the executive function tests in the MCI patients. In contrast, in both groups the retrospective memory complaints were related to a task switching test. The findings are discussed with respect to differences between the three groups in cognitive abilities, attention to failures of, use of mnemonic aids for, and everyday demands of prospective and retrospective memory.

Event-based prospective memory failure in amnestic mild cognitive impairment

2011 ◽  
Vol 49 (8) ◽  
pp. 2209-2216 ◽  
Author(s):  
Alberto Costa ◽  
Roberta Perri ◽  
Silvia Zabberoni ◽  
Francesco Barban ◽  
Carlo Caltagirone ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Amnestic Mild Cognitive Impairment ◽  
Memory Failure ◽  
Event Based

The Influence of Ongoing Task Change on Event-based Prospective Memory in Patients with Mild Cognitive Impairment

2014 ◽  
Vol 46 (10) ◽  
pp. 1454
Author(s):  
Lijuan WANG ◽  
Zhe ZHANG ◽  
Changfeng ZHANG ◽  
Guangzheng LI ◽  
Zhanyu YU
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Ongoing Task ◽  
Task Change ◽  
Event Based

scholarly journals Evaluating Different Aspects of Prospective Memory in Amnestic and Nonamnestic Mild Cognitive Impairment

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Rene Hernandez Cardenache ◽  
Lizmar Burguera ◽  
Amarilis Acevedo ◽  
Rosie Curiel ◽  
David A. Loewenstein
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Prospective Memory ◽  
Memory Deficits ◽  
Amnestic Mild Cognitive Impairment ◽  
Significant Feature ◽  
Retrospective Memory ◽  
Cognitively Normal ◽  
Common Complaint ◽  
Unique Aspect

Prospective memory, the inability to remember an intended action, is a common complaint, but not formally assessed in most clinical and research studies of mild cognitive impairment (MCI). In this study, patients with amnestic mild cognitive impairment (aMCI), non-amnestic cognitive impairment (naMCI), and cognitively normal (CN) elders were assessed using the Miami Prospective Memory Test (MPMT). A unique aspect of the paradigm was that participants were scored for intention to perform, accuracy in recollection for specific elements of the task, and the need for reminder cues. Excellent test-retest stability was obtained for MPMT Event-Related (ER), combined Time-Related (TR) subscales, and total MPMT score for aMCI subjects. MPMT impairments were observed in 48.6% of aMCI, 29.4% of naMCI, and 10.0% of normal elderly participants. Prospective memory deficits were common in participants with aMCI, and occurred in almost a third of naMCI participants. Intention to perform and need for reminder cues were significantly more impaired than retrospective memory for specific details of the task. It is concluded that assessment of different elements of prospective memory is important in MCI research and that inability to remember intended actions is a significant feature in those as risk for Alzheimer’s disease.

Sign in / Sign up

Export Citation Format

Share Document