Primary mucosa-associated lymphoid tissue lymphoma of the thyroid with concomitant papillary carcinoma

2014 ◽  
Vol 13 (4) ◽  
pp. 490-492
Author(s):  
Shaakir Hasan ◽  
Aruna Turaka

AbstractObjectivePapillary thyroid carcinoma combined with thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare and there is no standard management.Case reportWe report a rare association of MALT lymphoma of thyroid in a 60-year-old woman with Hashimoto's thyroiditis along with an incidental focus of papillary carcinoma.ConclusionPatients with Hashimoto's thyroiditis are prone to develop other thyroid pathology, including rare tumours such as MALT lymphoma. The differential diagnosis for a neoplasm in such patients should be wide.

2010 ◽  
Vol 54 (4) ◽  
pp. 425-428 ◽  
Author(s):  
Giulianno Molina de Melo ◽  
Danilo Anunciatto Sguilar ◽  
Cyntia Moniz Figueira Petiti ◽  
André Gustavo Gumz Eichstaedt ◽  
Rogério Ramos Caiado ◽  
...  

The objective of this study was to describe the rare thyroid MALT lymphoma concomitant with papillary thyroid carcinoma in a male patient who was submitted to total thyroidectomy. Treatment and follow-up issues are addressed. Male patient complains of fast thyroid enlargement without lymphadenophaty and normal clinical exams. Total thyroidectomy was indicated and performed without any complications. The pathology showed multicentric papillary thyroid carcinoma, concomitant thyroid MALT lymphoma and Hashimoto's thyroiditis. The immunohistochemistry assay was positive for CD 20, CD 43, CD 79, AE1/AE3. The staging studies showed no evidence of both metastasis, Ann Harbor stage IE, without B symptoms. After RIT no further radiotherapy or chemotherapy was indicated. Nowadays the thyroglobulin is undetectable, without recurrences at two years of follow-up. It was concluded that primary thyroid MALT lymphoma is uncommon being the papillary thyroid carcinoma more frequent. Both occurring concomitantly is very rare and the treatment has to prioritize the tumor of worst prognosis at the discovery moment.


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