Practical lookup tables for ensuring target coverage in a clinical setup for skin cancer electron therapy

2017 ◽  
Vol 17 (2) ◽  
pp. 205-211
Author(s):  
Yongsook C. Lee ◽  
Yongbok Kim

AbstractAimTo create practical lookup tables containing percent depth dose (PDD) and profile parameters of electron beams and to demonstrate clinical application of the lookup tables to skin cancer treatment to ensure target coverage in a clinical setup.Materials and methodsFor 6 and 9 MeV electron energies, PDDs and profiles at clinically relevant depths [i.e., R95 (distal depth of 95% maximum dose), R90, R85 and R80] were measured in water at 100 cm source-to-surface distance for an 10×10 cm2 open field and circular cutouts with diameters of 4, 5, 6, 7 and 8 cm. Then PDD parameters along with profile parameters such as width of isodose lines and penumbra at the clinically relevant depths were determined. Output factors for the cutouts were measured at dmax in water and solid water.ResultsWith PDD and profile parameters, dosimetry lookup tables were generated. Based upon the lookup tables, target coverage at prescribed depths was retrospectively reviewed for three skin cancer cases. The lookup tables suggested larger cutouts for adequate target coverage.FindingsDosimetry lookup tables for electron beam therapy should include profile parameters at clinically relevant depths and be provided to clinicians to ensure target coverage in a clinical setup.

2008 ◽  
Vol 7 (3) ◽  
pp. 133-140 ◽  
Author(s):  
James C.L. Chow ◽  
Grigor N. Grigorov ◽  
Kathryn Ross

AbstractDosimetric changes caused by the positional uncertainty of centring a small electron cutout to the machine central beam axis (CAX) of the linear accelerator (linac) were investigated. First, six circular cutouts with 4 cm diameter were made with their centres shifted off from the machine CAX for 0, 2, 4, 6, 8 and 10 mm using the 6 × 6 cm2 applicator. Then, the percentage depth doses (PDDs) at the machine CAX and cutout centre were measured using the 4, 9 and 16 MeV clinical electron beams produced by a Varian 21 EX linac. The cross- and in-line axis beam profiles were measured at depth of maximum dose (dm) and source-to-surface distance equal to 100 cm using a scanning water tank system and diode detector. When the cutout centre was shifted away from machine CAX for the electron beam with low energy of 4 MeV, the dm, depths of the 80 (R80) and 90% (R90) depth dose at the machine CAX had no significant change (<0.1 mm). For higher energies of 9 and 16 MeV beams, the dm were reduced with 0.45 and 1.63 mm per mm off-axis shift between the cutout centre and the machine CAX, respectively. The R80 and R90 were reduced with 0.7 mm per mm off-axis shift for both energies. When there was a 4 mm off-axis shift, the relative output factors for the 4, 9 and 16 MeV beams were reduced with 0.8, 1.6 and 0.5%, respectively. The isodose coverage of the in-line axis beam profile was reduced when the cutout centre was shifted away from machine CAX. It is important for radiation oncologists, dosimetrists, therapists and physicists to note such dosimetric changes in the electron radiotherapy to the patient, because such positional uncertainty is unavoidable in fabricating an electron cutout in the mould room.


2022 ◽  
Vol 12 (2) ◽  
pp. 600
Author(s):  
Serenella Russo ◽  
Silvia Bettarini ◽  
Barbara Grilli Leonulli ◽  
Marco Esposito ◽  
Paolo Alpi ◽  
...  

High-energy small electron beams, generated by linear accelerators, are used for radiotherapy of localized superficial tumours. The aim of the present study is to assess the dosimetric performance under small radiation therapy electron beams of the novel PTW microSilicon detector compared to other available dosimeters. Relative dose measurements of circular fields with 20, 30, 40, and 50 mm aperture diameters were performed for electron beams generated by an Elekta Synergy linac, with energy between 4 and 12 MeV. Percentage depth dose, transverse profiles, and output factors, normalized to the 10 × 10 cm2 reference field, were measured. All dosimetric data were collected in a PTW MP3 motorized water phantom, at SSD of 100 cm, by using the novel PTW microSilicon detector. The PTW diode E and the PTW microDiamond were also used in all beam apertures for benchmarking. Data for the biggest field size were also measured by the PTW Advanced Markus ionization chamber. Measurements performed by the microSilicon are in good agreement with the reference values for all the tubular applicators and beam energies within the stated uncertainties. This confirms the reliability of the microSilicon detector for relative dosimetry of small radiation therapy electron beams collimated by circular applicators.


Author(s):  
Samira Yazdani ◽  
Fateme Shirani Takabi ◽  
Abolfazl Nickfarjam

Purpose: Commissioning of a linear accelerator is a process of acquiring a set of data used for patient treatment. This article presents the beam data measurement results from the commissioning of a VitalBeamTM linac. Materials and Methods: Dosimetric properties for 6,10, and 15 MV photon beams and 6, 9, 12, and 16 MeV electron beams have been performed. Parameters, including Percentage Depth Dose (PDD), depth dose profile, symmetry, flatness, quality index, output factors, and the vital data for Treatment Planning System (TPS) commissioning were measured. The imported data were checked by CIRS phantom accordingly to IAEA TRS-430, TECDOC. Eight different positions of CIRS phantom CT were planned and treated. Finally, the calculated dose at a determined position was compared with measuring data to TPS validation. Results: After comparing 84 points in a different plan, the 83 points were in agreement with the criteria, and just for one point in 15 MV failed. Conclusion: Commissioning of dose and field flatness and symmetry are in tolerance intervals given by Varian. This proves that the studied lines meet the specification and can be used in clinical practice with all available electron and photon energies.


2019 ◽  
Vol 30 (1) ◽  
pp. 14-17
Author(s):  
Intan Dillia Nurhadi ◽  
Ridwan Ramdani ◽  
Freddy Haryanto ◽  
Yudha Satya Perkasa ◽  
Mada Sanjaya

Research was conducted to analyze the effect of changes in the distance radiation source to the surface it is called the medium Source to Surface Distance (SSD) and wide exposure field (Field Size) on the distribution of the dose in linear air Accelerator (LINAC) using Monte Carlo - EGSnrc. Monte Carlo simulation is used for modeling and simulation head linac at BEAMnrc. Virtual model of the linac is made based on the data characteristics of the aircraft Linac Varian Clinac iX then its output obtained information characteristic photon beam using BEAMDP, while modeling and simulation phantom done on DOSXYZnrc with the size of the phantom is (40x40x40) cm3 , with the material in the form of water, using a beam of photons 6 MV, testing variation SSD at 80 cm, 90 cm, 100.1 cm, 110 cm, 120 cm and variation field size is (6x6) cm2, (10x10) cm2, (20x20) cm2 to obtain disribution of dosage form of curves Percentage Depth dose (PDD) and Profile dose. The results showed that the smaller distance radiation source to the surface of the medium (SSD) and the greater the broad field (field size), then increasing the dose distribution is obtained. In the SSD and Field Size variation, the radiation dose will continue to rise significantly from the surface of the medium 0 cm to a depth of maximum dose (Dmax), then the dose began to decline after passing the depth Dmax.


Author(s):  
Serenella Russo ◽  
Silvia Bettarini ◽  
Barbara Grilli Leonulli ◽  
Marco Esposito ◽  
Paolo Alpi ◽  
...  

High-energy small electron beams generated by linear accelerators are used for radiotherapy of localized superficial tumors. The aim of the present study is to assess the dosimetric performance under small radiation therapy electron beams of the novel PTW microSilicon detector by comparison with commercially available dosimeters. Relative dose measurements of circular fields with 20, 30, 40 and 50 mm aperture diameters were performed for 4 to 12 MeV energy range of electron beams generated by an Elekta Synergy linac. Percentage depth dose, transverse profiles and output factors normalized to the 10 &times; 10 cm2 reference field were measured. All dosimetric data were collected in a PTW MP3 motorized water phantom at SSD of 100cm by using the novel PTW microSilicon detector. The PTW diode E and the PTW microDiamond were also used in all beam aperture for benchmarking. Data for the biggest field size were also measured by the PTW Advanced Markus ionization chamber.Measurements performed by the microSilicon are in good agreement with the reference values for all the tubular applicators and beam energies, within the stated uncertainties. This confirms the reliability of the microSilicon detector for relative dosimetry of small radiation therapy electron beams collimated by tubular applicators.


Radiology ◽  
1978 ◽  
Vol 126 (1) ◽  
pp. 249-251 ◽  
Author(s):  
Faiz M. Khan ◽  
Wilfred Sewchand ◽  
Seymour H. Levitt

Author(s):  
H Dowlatabadi ◽  
A A Mowlavi ◽  
M Ghorbani ◽  
S Mohammadi ◽  
F Akbari

Introduction: Radiation therapy using electron beams is a promising method due to its physical dose distribution. Monte Carlo (MC) code is the best and most accurate technique for forespeaking the distribution of dose in radiation treatment of patients.Materials and Methods: We report an MC simulation of a linac head and depth dose on central axis, along with profile calculations. The purpose of the present research is to carefully analyze the application of MC methods for the calculation of dosimetric parameters for electron beams with energies of 8–14 MeV at a Siemens Primus linac. The principal components of the linac head were simulated using MCNPX code for different applicators. Results: The consequences of measurements and simulations revealed a good agreement. Gamma index values were below 1 for most points, for all energy values and all applicators in percent depth dose and dose profile computations. A number of states exhibited rather large gamma indices; these points were located at the tail of the percent depth dose graph; these points were less used in in radiotherapy. In the dose profile graph, gamma indices of most parts were below 1. The discrepancies between the simulation results and measurements in terms of Zmax, R90, R80 and R50 were insignificant. The results of Monte Carlo simulations showed a good agreement with the measurements. Conclusion: The software can be used for simulating electron modes of a Siemens Primus linac when direct experimental measurements are not feasible.


2021 ◽  
Vol 27 (1) ◽  
pp. 25-29
Author(s):  
Labinot Kastrati ◽  
Gezim Hodolli ◽  
Sehad Kadiri ◽  
Elvin Demirel ◽  
Lutfi Istrefi ◽  
...  

Abstract Introduction: The aim of this study is to analyze the gradient of percentage depth dose for photon and electron beams of LINACs and to simplify the data set. Materials and Methods: Dosimetry measurements were performed in accordance with Technical Reports Series No. 398 IAEA. Results and discussion: The gradient of percentage depth dose was calculated and compared with the available published data. Conclusion: Instead of percentage depth dose for increasing and decreasing parts, the findings suggest using only two numbers for specific gradient of dose, separately. In this way, they can replace the whole set of the percentage depth dose (PDD).


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