scholarly journals Diagnostics of Anodic Stripping Mechanisms under Square-Wave Voltammetry Conditions Using Bismuth Film Substrates

2012 ◽  
Vol 84 (10) ◽  
pp. 4429-4436 ◽  
Author(s):  
Valentin Mirceski ◽  
Samo B. Hocevar ◽  
Bozidar Ogorevc ◽  
Rubin Gulaboski ◽  
Ivan Drangov
2013 ◽  
Vol 78 (12) ◽  
pp. 2131-2140 ◽  
Author(s):  
Aleksandar Mladenovic ◽  
Vladislava Jovanovic ◽  
Slobodan Petrovic ◽  
Dusan Mijin ◽  
Sasa Drmanic ◽  
...  

The determination of clopidogrel, an antiplatelet agent, was performed at a gold electrode in pH 3.7 acetate buffer using cyclic voltammetry (CV) and square wave voltammetry (SWV). Each voltammogram is characterized by the well defined peak at approximately 1.0 V. The current of anodic stripping peak exhibits linear dependence on the clopidogrel concentration in a range from 317.89 mg cm-3 to 935.16 mg cm-3. The obtained linearity was applied to determine clopidogrel amount in the tablet form of pharmaceutical preparation (Plavix?). The results were compared to the UV spectrophotometric and HPLC method.


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