Understanding the Conformational Impact of Chemical Modifications on Monoclonal Antibodies with Diverse Sequence Variation Using Hydrogen/Deuterium Exchange Mass Spectrometry and Structural Modeling

2014 ◽  
Vol 86 (7) ◽  
pp. 3468-3475 ◽  
Author(s):  
Aming Zhang ◽  
Ping Hu ◽  
Paul MacGregor ◽  
Yu Xue ◽  
Haihong Fan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibodies ◽  
Sequence Variation ◽  
Structural Modeling ◽  
Deuterium Exchange ◽  
Hydrogen Deuterium Exchange ◽  
Chemical Modifications ◽  
Exchange Mass Spectrometry ◽  
Hydrogen Deuterium ◽  
Deuterium Exchange Mass Spectrometry

scholarly journals Hydrogen-Deuterium Exchange Mass Spectrometry of Phosphorylation Induced Changes in Smooth Muscle Myosin

2013 ◽  
Vol 104 (2) ◽  
pp. 452a
Author(s):  
K. Ilker Sen ◽  
Brian D. Haldeman ◽  
Richard Brizendine ◽  
Roger Mercer ◽  
Christine R. Cremo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Smooth Muscle ◽  
Smooth Muscle Myosin ◽  
Deuterium Exchange ◽  
Hydrogen Deuterium Exchange ◽  
Exchange Mass Spectrometry ◽  
Hydrogen Deuterium ◽  
Deuterium Exchange Mass Spectrometry ◽  
Induced Changes ◽  
Muscle Myosin
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