Multi-Attribute Monitoring of Complex Erythropoetin Beta Glycosylation by GluC Liquid Chromatography–Mass Spectrometry Peptide Mapping

Integration of liquid chromatography mass spectrometry with a heavy peptide response curve accurately measures unprocessed C-terminal lysine during peptide mapping analysis of therapeutic antibodies in a single run

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2021.113963 ◽

2021 ◽

Vol 197 ◽

pp. 113963

Author(s):

Tyler Greer ◽

Reid O’Brien Johnson ◽

Milos Cejkov ◽

Xiaojing Zheng ◽

Ning Li

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Response Curve ◽

Peptide Mapping ◽

Therapeutic Antibodies ◽

Mapping Analysis

Fast and efficient digestion of adeno associated virus (AAV) capsid proteins for liquid chromatography mass spectrometry (LC-MS) based peptide mapping and post translational modification analysis (PTMs)

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2021.114427 ◽

2021 ◽

pp. 114427

Author(s):

Felipe Guapo ◽

Lisa Strasser ◽

Silvia Millán-Martín ◽

Ian Anderson ◽

Jonathan Bones

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Peptide Mapping ◽

Capsid Proteins ◽

Post Translational Modification ◽

Adeno Associated Virus ◽

Enhanced sensitivity for peptide mapping with electrospray liquid chromatography-mass spectrometry in the presence of signal suppression due to trifluoroacetic acid-containing mobile phases

10.1016/0021-9673(95)00175-m ◽

1995 ◽

Vol 712 (1) ◽

pp. 177-190 ◽

Cited By ~ 251

Author(s):

Alex Apffel ◽

Steven Fischer ◽

Gerson Goldberg ◽

Paul C. Goodley ◽

Frank E. Kuhlmann

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Trifluoroacetic Acid ◽

Peptide Mapping ◽

Enhanced Sensitivity ◽

Signal Suppression ◽

Mobile Phases

Analysis of core histones by liquid chromatography–mass spectrometry and peptide mapping

Journal of Chromatography B ◽

10.1016/s1570-0232(02)00631-1 ◽

2003 ◽

Vol 783 (1) ◽

pp. 173-179 ◽

Cited By ~ 29

Author(s):

Kangling Zhang ◽

Hui Tang

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Peptide Mapping ◽

Core Histones

Fully Automated Peptide Mapping Multi-Attribute Method by Liquid Chromatography–Mass Spectrometry with Robotic Liquid Handling System

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2021.113988 ◽

2021 ◽

pp. 113988

Author(s):

Chen Qian ◽

Ben Niu ◽

Rod Brian Jimenez ◽

Jihong Wang ◽

Methal Albarghouthi

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Peptide Mapping ◽

Handling System ◽

Liquid Handling ◽

Rapid high-sensitivity peptide mapping by liquid chromatography—mass spectrometry

10.1016/s0021-9673(99)87018-6 ◽

1993 ◽

Vol 646 (1) ◽

pp. 169-174 ◽

Cited By ~ 18

Author(s):

Kuldip Mock ◽

Mark Hail ◽

Iain Mylchreest ◽

Joe Zhou ◽

Ken Johnson ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Peptide Mapping ◽

High Sensitivity ◽

Characterization of glycosylation sites for a recombinant IgG1 monoclonal antibody and a CTLA4-Ig fusion protein by liquid chromatography–mass spectrometry peptide mapping

10.1016/j.chroma.2011.08.089 ◽

2011 ◽

Vol 1218 (45) ◽

pp. 8140-8149 ◽

Cited By ~ 33

Author(s):

Jacob Bongers ◽

John Devincentis ◽

Jinmei Fu ◽

Peiqing Huang ◽

David H. Kirkley ◽

...

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibody ◽

Liquid Chromatography ◽

Fusion Protein ◽

Peptide Mapping ◽

Glycosylation Sites ◽

Igg1 Monoclonal Antibody

Evaluation of enzymatic digestion and liquid chromatography-mass spectrometry peptide mapping of the integral membrane protein bacteriorhodopsin

Electrophoresis ◽

10.1002/1522-2683(200209)23:18<3224::aid-elps3224>3.0.co;2-# ◽

2002 ◽

Vol 23 (18) ◽

pp. 3224-3232 ◽

Cited By ~ 18

Author(s):

Kim K. Hixson ◽

Nestor Rodriguez ◽

David G. Camp ◽

Eric F. Strittmatter ◽

Mary S. Lipton ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Membrane Protein ◽

Peptide Mapping ◽

Integral Membrane Protein ◽

Enzymatic Digestion ◽

Miniaturized on-line proteolysis–capillary liquid chromatography–mass spectrometry for peptide mapping of lactate dehydrogenase

10.1016/s0021-9673(03)00647-2 ◽

2003 ◽

Vol 998 (1-2) ◽

pp. 83-91 ◽

Cited By ~ 31

Author(s):

Jenny Samskog ◽

Dan Bylund ◽

Sven P Jacobsson ◽

Karin E Markides

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Lactate Dehydrogenase ◽

Peptide Mapping ◽

Capillary Liquid Chromatography ◽

On Line ◽

Capillary Liquid

Liquid Chromatography/Mass Spectrometry, MS/MS and Time of Flight MS

10.1021/bk-2003-0850 ◽

2003 ◽

Cited By ~ 14

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Time Of Flight ◽