Subcellular Raman Microspectroscopy Imaging of Nucleic Acids and Tryptophan for Distinction of Normal Human Skin Cells and Tumorigenic Keratinocytes

2015 ◽  
Vol 87 (13) ◽  
pp. 6778-6785 ◽  
Author(s):  
Paola Piredda ◽  
Manuel Berning ◽  
Petra Boukamp ◽  
Andreas Volkmer
Keyword(s):  
Nucleic Acids ◽  
Human Skin ◽  
Raman Microspectroscopy ◽  
Normal Human Skin ◽  
Skin Cells ◽  
Normal Human ◽  
Human Skin Cells

scholarly journals Sublethal Doses of Surfactants Induce Premature Senescence in Normal Human Skin Cells

2011 ◽  
Vol 75 (7) ◽  
pp. 1395-1398 ◽  
Author(s):  
Yoshimi YAMAKAMI ◽  
Kensuke MIKI ◽  
Morio ENDOH ◽  
Ryuzo YONEKURA ◽  
Ryo UKEKAWA ◽  
...  
Keyword(s):  
Human Skin ◽  
Premature Senescence ◽  
Normal Human Skin ◽  
Skin Cells ◽  
Normal Human ◽  
Sublethal Doses ◽  
Human Skin Cells

Oxidative stress induced by UV-B and sunlight mediated photoactivation of carbazole inhibits normal human skin cells physiology

2018 ◽  
Vol 120 ◽  
pp. S48
Author(s):  
Ajeet K. Srivastav ◽  
Jyoti Singh ◽  
Divya Dubey ◽  
Deepti Chopra ◽  
Mohd. Anas ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Skin ◽  
Normal Human Skin ◽  
Skin Cells ◽  
Normal Human ◽  
Human Skin Cells

Thymidine dinucleotide enhance DNA repair in normal human skin cells

1996 ◽  
Vol 6 (SUPPLEMENT 1) ◽  
pp. S51
Author(s):  
C. Magnoni ◽  
M. S. Eller ◽  
D. A. A. Giannetti ◽  
B. A. Gilchrest
Keyword(s):  
Dna Repair ◽  
Human Skin ◽  
Normal Human Skin ◽  
Skin Cells ◽  
Normal Human ◽  
Human Skin Cells

scholarly journals The synthetic flavagline FL3 spares normal human skin cells from its cytotoxic effect via an activation of Bad

2019 ◽  
Vol 60 ◽  
pp. 27-35 ◽  
Author(s):  
Fathi Emhemmed ◽  
Sarah Ali Azouaou ◽  
Sarah Hassan ◽  
Ray Lefevbre ◽  
Laurent Désaubry ◽  
...  
Keyword(s):  
Human Skin ◽  
Cytotoxic Effect ◽  
Normal Human Skin ◽  
Skin Cells ◽  
Normal Human ◽  
Human Skin Cells

scholarly journals A comparative study between human skin substitutes and normal human skin using Raman microspectroscopy

2014 ◽  
Vol 10 (6) ◽  
pp. 2703-2711 ◽  
Author(s):  
Marie Leroy ◽  
Jean-François Labbé ◽  
Marise Ouellet ◽  
Jessica Jean ◽  
Thierry Lefèvre ◽  
...  
Keyword(s):  
Comparative Study ◽  
Human Skin ◽  
Raman Microspectroscopy ◽  
Skin Substitutes ◽  
Normal Human Skin ◽  
Normal Human

The attachment of Schistosoma mansoni cercariae to human skin cells

Parasitology ◽  
2002 ◽  
Vol 124 (1) ◽  
pp. 25-30 ◽  
Author(s):  
N. KHAMMO ◽  
A. BARTLETT ◽  
R. H. CLOTHIER ◽  
P. J. WHITFIELD
Keyword(s):  
Schistosoma Mansoni ◽  
Human Skin ◽  
Cell Types ◽  
Laboratory Animals ◽  
Normal Human Skin ◽  
Skin Cells ◽  
Skin Cell ◽  
Different Types ◽  
Human Skin Cells

Most of our knowledge about the process of penetration of skin, by cercariae of Schistosoma mansoni, has been gained from studies carried out in vivo with laboratory animals. Human skin is significantly different from that of other animals but there are obvious practical difficulties in directly studying attachment and penetration with human skin. Techniques have been developed which enable a 3-dimensional ‘skin equivalent’ to be grown in tissue culture, made from different types of human skin cells. The aim of the present study was to investigate cercarial interactions with confluent cultures of the individual skin cell types that make up normal human skin and which will be used to construct a multi-component model. Cercariae behaved differently towards the various cell types tested. They responded least to monolayers of endothelial cells and most to primary keratinocytes, derived from human foreskin and differentiated at an air/liquid interface. This study demonstrates, therefore, that cercariae are capable of distinguishing between different types of skin cells and they preferentially attach to differentiated cells which form the epidermis.

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