Boronated Condensed DNA as a Heterochromatic Radiation Target Model

2021 ◽  
Vol 22 (4) ◽  
pp. 1675-1684
Author(s):  
Christopher C. Perry ◽  
José Ramos-Méndez ◽  
Jamie R. Milligan
Keyword(s):  
Author(s):  
George C. Ruben ◽  
Kenneth A. Marx

Certain double stranded DNA bacteriophage and viruses are thought to have their DNA organized into large torus shaped structures. Morphologically, these poorly understood biological DNA tertiary structures resemble spermidine-condensed DNA complexes formed in vitro in the total absence of other macromolecules normally synthesized by the pathogens for the purpose of their own DNA packaging. Therefore, we have studied the tertiary structure of these self-assembling torus shaped spermidine- DNA complexes in a series of reports. Using freeze-etch, low Pt-C metal (10-15Å) replicas, we have visualized the microscopic DNA organization of both calf Thymus( CT) and linear 0X-174 RFII DNA toruses. In these structures DNA is circumferentially wound, continuously, around the torus into a semi-crystalline, hexagonal packed array of parallel DNA helix sections.


2012 ◽  
Author(s):  
Wendi Adair ◽  
Christine Klamert ◽  
Thiam Phouthonephackdy ◽  
Huadong Yang

2021 ◽  
Vol 287 ◽  
pp. 112303
Author(s):  
María Rosa Pino-Otín ◽  
Elisa Langa ◽  
Jonatan Val ◽  
Ana M. Mainar ◽  
Diego Ballestero

Zygote ◽  
1997 ◽  
Vol 5 (3) ◽  
pp. 213-217 ◽  
Author(s):  
J. Fulka ◽  
N.L. First ◽  
C. Lee ◽  
J. Fulka ◽  
R.M. Moor

SummaryImmature mouse oocytes (germinal vesicle stage, GV), oocytes at different stages during maturation (prometaphase to anaphase I) and matured oocytes (metaphase II arrested) were cultured in 6-dimethylaminopurine (6-DMAP)-supplemented medium also containing bromodeoxyuridine for the assessment of DNA replication in these cells. Immature oocytes remained arrested at the GV stage and DNA replication was never detected in them. On the other hand, oocytes at the prometaphase to anaphase-telophase I stages responded to 6-DMAP treatment by forming nuclei which synthesised DNA. Mature (metaphase II) oocytes did not respond to 6-DMAP and their chromatin remained condensed. DNA synthesis could even be induced in GV-staged oocytes, but only when they were fused to freshly activated oocytes and incubated in 6-DMAP-supplemented medium.


Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2841
Author(s):  
Khizer Mehmood ◽  
Abdul Jalil ◽  
Ahmad Ali ◽  
Baber Khan ◽  
Maria Murad ◽  
...  

Despite eminent progress in recent years, various challenges associated with object tracking algorithms such as scale variations, partial or full occlusions, background clutters, illumination variations are still required to be resolved with improved estimation for real-time applications. This paper proposes a robust and fast algorithm for object tracking based on spatio-temporal context (STC). A pyramid representation-based scale correlation filter is incorporated to overcome the STC’s inability on the rapid change of scale of target. It learns appearance induced by variations in the target scale sampled at a different set of scales. During occlusion, most correlation filter trackers start drifting due to the wrong update of samples. To prevent the target model from drift, an occlusion detection and handling mechanism are incorporated. Occlusion is detected from the peak correlation score of the response map. It continuously predicts target location during occlusion and passes it to the STC tracking model. After the successful detection of occlusion, an extended Kalman filter is used for occlusion handling. This decreases the chance of tracking failure as the Kalman filter continuously updates itself and the tracking model. Further improvement to the model is provided by fusion with average peak to correlation energy (APCE) criteria, which automatically update the target model to deal with environmental changes. Extensive calculations on the benchmark datasets indicate the efficacy of the proposed tracking method with state of the art in terms of performance analysis.


2007 ◽  
Vol 79 (5) ◽  
pp. 58001 ◽  
Author(s):  
Y Murayama ◽  
H Wada ◽  
M Sano

Solar Physics ◽  
1983 ◽  
Vol 88 (1-2) ◽  
Author(s):  
J.C. Brown ◽  
V.A. Carlaw ◽  
D. Cromwell ◽  
S.R. Kane
Keyword(s):  
X Ray ◽  

2021 ◽  
Vol 30 (4) ◽  
pp. 74-89
Author(s):  
A. V. Ershov ◽  
V. B. Korobko

The article addresses the problem of bridging the divide between the present-day technological advancement, primarily in the field of normative legal and technical regulation of fire safety, and the qualification of persons, authorized to regulate relations in fire safety assurance (hereinafter — “Authorized persons”) in the context of transition of the state regulation of fire safety relations from an obsolete standard target model to a new analytical and scenario-based (risk-oriented) target model used to make decisions in the area of control over the safe condition of the technosphere in view of a sudden increase in the dynamics of sociocultural processes.The Education and Research Supervision Unit of the State Fire Academy of the EMERCOM of Russia (the Ministry for Civil Defense, Emergencies, and Elimination of Consequences of Natural Disasters), responsible for the drafting of suggestions concerning the implementation of point 10, Minutes № 1 of the meeting of the workgroup of EMERCOM of Russia on May 20, 2019 “Regarding the arrangement of interaction with the management authorities of the institutional firefighting service of executive federal authorities and organizations”, has developed “The list of milestones of professional culture for the persons responsible for regulating relations in the field of fire safety for the period of transition from a standard target model to the risk model of controlling, supervisory, and authorization-related activities” (hereinafter — “the List”).This List represents a basic set of conceptual professional milestones, whose attainment enables authorized persons to re-focus their conscience from an obsolete standard paradigm, used to make decisions in the area of fire safety, to a new risk-oriented one.Given the focus of this article, it defines some, or the most significant, milestones of professional risk-oriented culture of authorized persons.


2014 ◽  
Vol 575 ◽  
pp. 337-342
Author(s):  
Wei Shi Xie ◽  
Zhi Hua Xiao ◽  
Jian Tang

The millimeter-wave terminal guidance ammunition monitoring scanning field is small. The modified design is in order to improve the search section trajectory guidance. This study established seeker search area to capture the target model, which leads to the missile engine unpowered glide distance formula after flameout. At the millimeter-wave terminal on the missiles contraction section ballistic. Each missile is designed for the flat road, the swash decline ballistic programs. Flat missile road program scans and does not shrink. Its flight speed falls and declines rapidly, has different gliding distance and terminal velocity. After the missile engine is flameout, its start-gliding speed is great. Ramp fell ballistic program enhances the air-air (or air-ground) guided missile’s gliding ability, helping to improve range. But shortcomings are that target tracking scanning domain contracts. Using the seeker optical axis in the pitch direction can achieve accurate positioning with the height precession. Two ballistic designs can both meet the target seeker’s scanning, thus effectively improve the striking precision.


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