Understanding Crystal Structures to Guide Form Selection of Active Pharmaceutical Ingredients: A Case Study of AZD9567

2021 ◽  
Author(s):  
Okky Dwichandra Putra ◽  
Jenny Ottosson ◽  
Sten O. Nilsson Lill ◽  
Anna Pettersen
Keyword(s):  
Crystal Structures ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Selection Of

scholarly journals Continuous one-flow multi-step synthesis of active pharmaceutical ingredients

2020 ◽  
Vol 5 (7) ◽  
pp. 1186-1197 ◽  
Author(s):  
Victor R. L. J. Bloemendal ◽  
Mathilde A. C. H. Janssen ◽  
Jan C. M. van Hest ◽  
Floris P. J. T. Rutjes
Keyword(s):  
Continuous Flow ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Flow Processes ◽  
Selection Of

This review highlights a selection of multistep continuous flow (one-flow) processes leading to the synthesis of active pharmaceutical ingredients (APIs).

Saccharin Salts of Active Pharmaceutical Ingredients, Their Crystal Structures, and Increased Water Solubilities

2005 ◽  
Vol 5 (6) ◽  
pp. 2299-2309 ◽  
Author(s):  
Rahul Banerjee ◽  
Prashant M. Bhatt ◽  
Nittala V. Ravindra ◽  
Gautam R. Desiraju
Keyword(s):  
Crystal Structures ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients

scholarly journals The A Priori Design and Selection of Ionic Liquids as Solvents for Active Pharmaceutical Ingredients

2017 ◽  
Vol 23 (23) ◽  
pp. 5498-5508 ◽  
Author(s):  
Andreas J. Kunov‐Kruse ◽  
Cameron C. Weber ◽  
Robin D. Rogers ◽  
Allan S. Myerson
Keyword(s):  
Ionic Liquids ◽  
A Priori ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Selection Of

Crystal-energy landscapes of active pharmaceutical ingredients using composite approaches

CrystEngComm ◽  
2019 ◽  
Vol 21 (40) ◽  
pp. 5995-6009 ◽  
Author(s):  
Luc M. LeBlanc ◽  
Erin R. Johnson
Keyword(s):  
Crystal Structures ◽  
Active Pharmaceutical Ingredients ◽  
Energy Landscapes ◽  
Pharmaceutical Ingredients ◽  
Composite Methods

Composite methods employing dispersion-corrected DFT consistently identify experimentally isolated polymorphs as the lowest-energy crystal structures of common APIs.

The challenge of improved secretory production of active pharmaceutical ingredients inSaccharomyces cerevisiae: A case study on human insulin analogs

2013 ◽  
Vol 110 (10) ◽  
pp. 2764-2774 ◽  
Author(s):  
Ali Kazemi Seresht ◽  
Eva A. Palmqvist ◽  
Gerd Schluckebier ◽  
Ingrid Pettersson ◽  
Lisbeth Olsson
Keyword(s):  
Human Insulin ◽  
Active Pharmaceutical Ingredients ◽  
Insulin Analogs ◽  
Pharmaceutical Ingredients ◽  
Secretory Production

scholarly journals Titanium Dioxide-Based Photocatalysts for Degradation of Emerging Contaminants including Pharmaceutical Pollutants

2021 ◽  
Vol 11 (18) ◽  
pp. 8674
Author(s):  
Rafal Krakowiak ◽  
Joanna Musial ◽  
Paweł Bakun ◽  
Marcin Spychała ◽  
Beata Czarczynska-Goslinska ◽  
...  
Keyword(s):  
Human Population ◽  
Emerging Contaminants ◽  
Water Remediation ◽  
Oxide Nanoparticles ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Chemical Pollutants ◽  
Pharmaceutical Pollutants ◽  
Soil And Water ◽  
Selection Of

Contamination of the environment has been a growing problem in recent years. Due to the rapid growth in human population, the expansion of cities, along with the development of industry, more and more dangerous chemicals end up in the environment, especially in soil and water. For the most part, it is not possible to effectively remove chemicals through traditional remediation techniques, because those used in treatment plants are not specifically designed for this purpose. Therefore, new approaches for water remediation are in great demand. Many efforts have been focused on applications of photocatalysis for the remediation of chemical pollutants including drugs. Titanium(IV) oxide nanoparticles have particularly been considered as potential photocatalysts due to their favorable properties. In this article, we present the problem of emerging contaminants including drugs and discuss the use of photocatalysts based on titanium(IV) oxide nanoparticles for their degradation. A wide selection of materials, starting from bare TiO2, via its hybrid and composite materials, are discussed including those based on carbonaceous materials or connections with macrocyclic structures. Examples of photodegradation experiments on TiO2-based materials including those performed with various active pharmaceutical ingredients are also included.

NPD process in active pharmaceutical ingredients industry: a case study in Iran

2017 ◽  
Vol 12 (1) ◽  
pp. 1
Author(s):  
Noor Mohammad Yaghoobi ◽  
Fatemeh S. Shahmehr ◽  
Seyed Mohammad Sadegh Khaksar ◽  
Narges Safari
Keyword(s):  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients
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