Nanoscale Mixed-Component Metal–Organic Frameworks with Photosensitizer Spatial-Arrangement-Dependent Photochemistry for Multimodal-Imaging-Guided Photothermal Therapy

2018 ◽  
Vol 30 (19) ◽  
pp. 6867-6876 ◽  
Author(s):  
Xiaohua Zheng ◽  
Lei Wang ◽  
Ming Liu ◽  
Pengpeng Lei ◽  
Feng Liu ◽  
...  
Nanoscale ◽  
2015 ◽  
Vol 7 (46) ◽  
pp. 19568-19578 ◽  
Author(s):  
Dan Yang ◽  
Guixin Yang ◽  
Shili Gai ◽  
Fei He ◽  
Guanghui An ◽  
...  

Metal–organic frameworks (MOFs) of Fe3O4/ZIF-8-Au25 were synthesized by a green and economic procedure, and exhibited high anti-cancer therapeutic efficacy for combined photodynamic and photothermal therapy.


2018 ◽  
Vol 14 (11) ◽  
pp. 1934-1943 ◽  
Author(s):  
Zhiyuan Shi ◽  
Chengchao Chu ◽  
Yang Zhang ◽  
Zhaojie Su ◽  
Huirong Lin ◽  
...  

Biosensors ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 299
Author(s):  
Xiangdong Lai ◽  
Hui Jiang ◽  
Xuemei Wang

Though there already had been notable progress in developing efficient therapeutic strategies for cancers, there still exist many requirements for significant improvement of the safety and efficiency of targeting cancer treatment. Thus, the rational design of a fully biodegradable and synergistic bioimaging and therapy system is of great significance. Metal organic framework (MOF) is an emerging class of coordination materials formed from metal ion/ion clusters nodes and organic ligand linkers. It arouses increasing interest in various areas in recent years. The unique features of adjustable composition, porous and directional structure, high specific surface areas, biocompatibility, and biodegradability make it possible for MOFs to be utilized as nano-drugs or/and nanocarriers for multimodal imaging and therapy. This review outlines recent advances in developing MOFs for multimodal treatment of cancer and discusses the prospects and challenges ahead.


2019 ◽  
Vol 7 (6) ◽  
pp. 994-1004 ◽  
Author(s):  
Jie Feng ◽  
Zhen Xu ◽  
Ping Dong ◽  
Wenqian Yu ◽  
Feng Liu ◽  
...  

Programmable metal–organic frameworks were prepared as efficient delivery vehicles for targeted and stimuli-responsive release of multi-therapeutics with excellent antitumor activity.


2020 ◽  
Vol 8 (5) ◽  
pp. 935-944 ◽  
Author(s):  
Xiaochun Hu ◽  
Yonglin Lu ◽  
Lulu Zhou ◽  
Lv Chen ◽  
Tianming Yao ◽  
...  

A multi-functional nanoplatform (PCN-CuS-FA-ICG) for combined photodynamic and photothermal therapy was presented, which demonstrated good inhibition of tumor growth.


2017 ◽  
Vol 9 (3) ◽  
pp. 2040-2051 ◽  
Author(s):  
Wen Cai ◽  
Haiyan Gao ◽  
Chengchao Chu ◽  
Xiaoyong Wang ◽  
Junqing Wang ◽  
...  

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