One-Pot Synthesis of α-Ketoamides from α-Keto Acids and Amines Using Ynamides as Coupling Reagents

Author(s):  
Jianting Ma ◽  
Xue Cui ◽  
Junyu Xu ◽  
Yinfeng Tan ◽  
Yan Wang ◽  
...  
2018 ◽  
Vol 54 (68) ◽  
pp. 9517-9520 ◽  
Author(s):  
Xiaobao Zeng ◽  
Chulong Liu ◽  
Weiguang Yang ◽  
Xingyong Wang ◽  
Xinyan Wang ◽  
...  

A two-step one-pot synthesis process of ynones was developed by cycloaddition of α-keto acids and 1-iodoalkynes followed by a ring-opening reaction.


Author(s):  
Di Wu ◽  
Chengcheng Li ◽  
Yong Jie Duan ◽  
Hongquan Yin ◽  
Fu-Xue Chen

The chlorothiocyanato difunctionalization reactions has been achieved to synthesis α-chlorothio/selenocyanato ketones, a variety of α-chlorothio/selenocyanato difunctional ketones is synthesized through one-pot strategy from β-ketone acids. The high yield and wide-range...


RSC Advances ◽  
2018 ◽  
Vol 8 (57) ◽  
pp. 32597-32600 ◽  
Author(s):  
De-Suo Yang ◽  
Juan Wang ◽  
Peng Gao ◽  
Zi-Jing Bai ◽  
Dong-Zhu Duan ◽  
...  

A one-pot approach to 1,2,4-triazolo[4,3-a]pyridines via KI-catalyzed oxidative cyclization was developed with good economical and environmental advantages.


2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>


2017 ◽  
Vol 7 (12) ◽  
pp. 1192-1195
Author(s):  
Y. I. Shaikh ◽  
G. M. Nazeruddin ◽  
Khursheed Ahmed

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