Nowadays, industries face very strong challenges because of the high competitiveness between them. In fact, they are required to offer products with high quality and minimum cost in the minimum time. Since most of the characteristics and costs of the product and its manufacturing process are fixed in the design phase, this paper is focused on this strategic phase. Indeed, a new integrated product design approach is presented. It considers at the same time design requirements, materials characteristics, manufacturing parameters and the assembly process specifications. The developed approach is quantitative. Actually, the decision making is based on all its steps on objective and subjective indicators. To validate the integrated approach, a case study on the Schrader Robot is developed. This application allows to choose the most appropriate materials, manufacturing processes and assembly solution of its different components.