Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

2021 ◽  
Author(s):  
Erdong Qu ◽  
Shangzhang Li ◽  
Jin Bai ◽  
Yan Zheng ◽  
Wanfang Li
Keyword(s):  
Cross Coupling ◽  
Nitro Compounds ◽  
Rapid Access

Short syntheses of 1-substituted dibenzothiophene derivatives

2021 ◽  
Vol 19 (9) ◽  
pp. 2000-2007
Author(s):  
Erin N. Welsh ◽  
Katherine N. Robertson ◽  
Alexander W. H. Speed
Keyword(s):  
Cross Coupling ◽  
One Pot ◽  
Chiral Amine ◽  
Rapid Access

A one-pot double benzyne cascade allows rapid access to 1-substituted dibenzothiophene derivatives, including cross-coupling partners and a chiral amine.

Rapid Access to Bi- and Tri-Functionalized Dibenzofurans and their Application in Selective Suzuki-Miyaura Cross Coupling Reactions

2018 ◽  
Vol 2018 (41) ◽  
pp. 5644-5656 ◽  
Author(s):  
Caroline Wern ◽  
Christian Ehrenreich ◽  
Dominik Joosten ◽  
Thorsten vom Stein ◽  
Herwig Buchholz ◽  
...  
Keyword(s):  
Cross Coupling ◽  
Coupling Reactions ◽  
Rapid Access ◽  
Cross Coupling Reactions

Ligand-Controlled Chemoselective One-Pot Synthesis of Dibenzothiazepinones and Dibenzoxazepinones via Twice Copper-Catalyzed Cross-Coupling

Synlett ◽  
2017 ◽  
Vol 28 (10) ◽  
pp. 1201-1208 ◽  
Author(s):  
Lanting Xu ◽  
Xianhua Pan ◽  
Yanyu Chen ◽  
Qiujun Peng ◽  
Rong Zhang ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Psychotropic Drug ◽  
Cross Coupling ◽  
One Pot ◽  
Highly Efficient ◽  
Rapid Access ◽  
One Pot Synthesis

A highly efficient and generally applicable protocol, starting from 2-bromobenzamides and 2-bromo(thio)phenols via twice copper-catalyzed couplings to afford dibenzothiazepines and dibenzoxazepinones has been developed. High levels of yield and chemoselectivity are achieved in a single-pot reaction by using an appropriate ligand. Moreover, this facile methodology allows rapid access to a variety of bio­active compounds and known psychotropic drug, which should broaden its application in organic synthesis.

Trimethylsilyl derivatives of aliphatic nitro compounds in α,β-C,C-cross-coupling

2000 ◽  
Vol 49 (5) ◽  
pp. 874-878 ◽  
Author(s):  
A. D. Dilman ◽  
I. M. Lyapkalo ◽  
S. L. Ioffe ◽  
Yu. A. Strelenko ◽  
V. A. Tartakovsky
Keyword(s):  
Cross Coupling ◽  
Nitro Compounds ◽  
Aliphatic Nitro Compounds ◽  
Trimethylsilyl Derivatives ◽  
Derivatives Of

ChemInform Abstract: Trimethylsilyl Derivatives of Aliphatic Nitro Compounds in α,β-C,C-Cross-Coupling.

ChemInform ◽  
2010 ◽  
Vol 31 (46) ◽  
pp. no-no
Author(s):  
A. D. Dilman ◽  
I. M. Lyapkalo ◽  
S. L. Ioffe ◽  
Yu. A. Strelenko ◽  
V. A. Tartakovsky
Keyword(s):  
Cross Coupling ◽  
Nitro Compounds ◽  
Aliphatic Nitro Compounds ◽  
Trimethylsilyl Derivatives ◽  
Derivatives Of

Copper(ii)-promoted oxidative C–H/C–H cross-coupling for rapid access to aza-BODIPY-indole derivatives with broad optical absorption

2017 ◽  
Vol 15 (33) ◽  
pp. 6888-6891 ◽  
Author(s):  
Ruyong Jiang ◽  
Xiuguang Yang ◽  
Di Wu
Keyword(s):  
Absorption Band ◽  
Optical Absorption ◽  
Cross Coupling ◽  
Indole Derivatives ◽  
Rapid Access

The absorption band of aza-BODIPY is remarkably broadened by coupling with indoles via a concise and inexpensive approach.

Palladium-Catalyzed Csp3–H Bond mono-Aroyloxylation of O-Alkyl Substituted 2,4,6-Trimethoxybenzaldoxime Ethers

Synlett ◽  
2018 ◽  
Vol 29 (09) ◽  
pp. 1249-1255
Author(s):  
Wen-Li Qiao ◽  
Ling-Yan Shao ◽  
Ya-Hua Hu ◽  
Li-Hao Xing ◽  
Ke-Zuan Deng ◽  
...  
Keyword(s):  
Aromatic Ring ◽  
Aliphatic Alcohol ◽  
Cross Coupling ◽  
Aliphatic Alcohols ◽  
Aromatic Acid ◽  
Rapid Access ◽  
Site Selectivity ◽  
Wide Range ◽  
Palladium Catalyzed ◽  
Directing Group

A palladium-catalyzed Csp3–H bond mono-aroyloxylation of O-alkyl substituted oxime ethers has been developed by using 2,4,6-trimethoxybenzaldoxime as an exo-type directing group with exclusive site-selectivity. With the wide range of masked aliphatic alcohol substrates and aromatic acid coupling partners, the protocol allows rapid access to various 2-alkyl substituted glycol derivatives in synthetically useful to good yields. The employed directing group is readily removed, accordingly affording valuable functionalized aliphatic alcohols. When the solvent from hybrid DCE/HFIP to CH3CN, non-directed oxidative cross-coupling is observed between the electron-rich aromatic ring of substrates and aromatic acid partners.

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