scholarly journals Correction to “Supramolecular Modular Approach toward Conveniently Constructing and Multifunctioning a pH/Redox Dual-Responsive Drug Delivery Nanoplatform for Improved Cancer Chemotherapy”

2020 ◽  
Author(s):  
Jia Liu ◽  
Xingxin Liu ◽  
Ye Yuan ◽  
Qilin Li ◽  
Bingcheng Chang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Chemotherapy ◽  
Modular Approach ◽  
Dual Responsive

Self-assembled micelles of PEG–poly(disulfide carbamate amine) copolymers for intracellular dual-responsive drug delivery

2016 ◽  
Vol 4 (5) ◽  
pp. 902-909 ◽  
Author(s):  
Chao Lin ◽  
Bo Lou ◽  
Jie Zhao ◽  
Rong Jin ◽  
Peng Zhao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Chemotherapy ◽  
Dual Responsive ◽  
Biodegradable Poly ◽  
Self Assembled

Self-assembled nanomicelles based on biodegradable poly(carbamate) copolymers are applicable for pH and redox dual-responsive release of doxorubicin (Dox) and cancer chemotherapy.

scholarly journals Loading and release of cancer chemotherapy drugs utilizing simultaneous temperature and pH-responsive nanohybrid

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Mohammad Dahri ◽  
Hossein Akbarialiabad ◽  
Ahmad Miri Jahromi ◽  
Reza Maleki
Keyword(s):  
Drug Delivery ◽  
Cancer Chemotherapy ◽  
Degradation Mechanism ◽  
Biochemical Properties ◽  
Release Mechanism ◽  
Chemotherapy Drugs ◽  
Drug Delivery Carrier ◽  
Dual Responsive ◽  
Walled Carbon Nanotubes ◽  
Chemotherapy Agents

Abstract Background Recently, the development of nanocarriers and the improvement of their biochemical properties have became of great importance. Single-walled carbon nanotubes (SWCNT) have many applications in drug delivery systems (DDS) as a common carbon-based structure. In the current work, the penetration, co-loading, and co-release of Doxorubicin (DOX) and Paclitaxel (PAX), as two cancer chemotherapy agents, were investigated using a novel modified copolymer with functionalized SWCNT. Results This study proposes a dual-responsive smart carrier that is sensitive to pH and temperature. The carrier consists of functionalized SWNT and Dimethyl acrylamide-trimethyl chitosan (DMAA-TMC) grafting on SWCNT. This suggested carrier was investigated by utilizing molecular simulations. Interaction energies between DOX, PAX, and carrier as well as the affinity of drugs to the nanocarrier were studied. The energy analysis of drug release and adsorption presented that DOX and PAX delivery using this carrier is selective and sensitive at healthy and cancerous conditions. The attraction of DMAA-TMC, as a biodegradable and biocompatible copolymer, with SWCNT showed that degradation mechanism in acidic environment deformed the copolymer. This leads to a smart release mechanism in an acidic cancerous tissue. Additionally, it improves hydrophilicity, optimum nano-particle size, and cell cytotoxicity concerns. Conclusions The simulation results manifested a significant contribution of DMAA-TMC in the adsorption and release of cancer chemotherapy drugs in normal and neoplastic tissues. The interaction of copolymer also improves the biocompatibility and biodegradability of the SWCNT. Smart drug delivery carrier can be a valuable nanohybrid for loading, transporting, and releasing of cancer chemotherapy drugs. Graphical abstract

O-nitrobenzyl Liposomes with Dual-responsive Release Capabilities for Drug Delivery

2021 ◽  
pp. 116016
Author(s):  
Weihe Yao ◽  
Chenyu Liu ◽  
Ning Wang ◽  
Hengjun Zhou ◽  
Farishta Shafiq ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dual Responsive

A Dual-Responsive Mesoporous Silica Nanoparticle for Tumor-Triggered Targeting Drug Delivery

Small ◽  
2013 ◽  
Vol 10 (3) ◽  
pp. 591-598 ◽  
Author(s):  
Dong Xiao ◽  
Hui-Zhen Jia ◽  
Jing Zhang ◽  
Chen-Wei Liu ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticle ◽  
Mesoporous Silica Nanoparticle ◽  
Dual Responsive

scholarly journals Iminoboronate-based dual-responsive micelles via subcomponent self-assembly for hydrophilic 1,2-diol-containing drug delivery

RSC Advances ◽  
2017 ◽  
Vol 7 (34) ◽  
pp. 21328-21335 ◽  
Author(s):  
Rujiang Ma ◽  
Chuan Zhang ◽  
Yong Liu ◽  
Chang Li ◽  
Yanling Xu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Dual Responsive

Iminoboronate-based dual-responsive micelles were fabricated via simple subcomponent self-assembly for delivery of hydrophilic 1,2-diol-containing drugs.

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