Multipolar Resonances of Ag Nanoparticle Arrays in Anodic Aluminum Oxide Nanochannels for Enhanced Hot Spot Intensity and Signal-to-Background Ratio in Surface-Enhanced Raman Scattering
Nanoporous anodic aluminum oxide (AAO) internalized with gold nanoparticles was utilized as an integrated platform miniaturized for consecutively performing on-chip PCR and downstream detection of the target DNA amplicons using surface-enhanced Raman scattering (SERS).