scholarly journals An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures

2016 ◽  
Vol 11 (6) ◽  
pp. 1661-1668 ◽  
Author(s):  
Paul J. Sapienza ◽  
Li Li ◽  
Tishan Williams ◽  
Andrew L. Lee ◽  
Charles W. Carter
Keyword(s):  
Ground State ◽  
Trna Synthetase ◽  
Tertiary Structures ◽  
Rate Enhancement ◽  
Catalytic Rate

Remarkably large solvolytic rate enhancement due to relief of ground state leaving group strain

1974 ◽  
Vol 96 (6) ◽  
pp. 1969-1970 ◽  
Author(s):  
Joel Slutsky ◽  
Richard C. Bingham ◽  
Paul V. R. Schleyer ◽  
W. C. Dickason ◽  
H. C. Brown
Keyword(s):  
Ground State ◽  
Rate Enhancement ◽  
Leaving Group ◽  
Group Strain

scholarly journals Correlated conformational fluctuations during enzymatic catalysis: Implications for catalytic rate enhancement

2008 ◽  
Vol 10 (7) ◽  
pp. 1319-1330 ◽  
Author(s):  
Kutay O. Alper ◽  
Manish Singla ◽  
Jennifer L. Stone ◽  
Carey K. Bagdassarian
Keyword(s):  
Enzymatic Catalysis ◽  
Rate Enhancement ◽  
Catalytic Rate

ChemInform Abstract: A REMARKABLY LARGE SOLVOLYTIC RATE ENHANCEMENT DUE TO RELIEF OF GROUND STATE LEAVING GROUP STRAIN

1974 ◽  
Vol 5 (22) ◽  
pp. no-no
Author(s):  
JOEL SLUTSKY ◽  
RICHARD C. BINGHAM ◽  
PAUL VON R. SCHLEYER ◽  
W. C. DICKASON ◽  
H. C. BROWN
Keyword(s):  
Ground State ◽  
Rate Enhancement ◽  
Leaving Group ◽  
Group Strain

Renilla Bioluminescence: A Morphologic Approach to the Location of Photocytes

1974 ◽  
Vol 32 ◽  
pp. 208-209
Author(s):  
Ben O. Spurlock ◽  
Milton J. Cormier
Keyword(s):  
Excited State ◽  
Ground State ◽  
Molecular Basis ◽  
Light Emission ◽  
Chemical Basis ◽  
Electronic Excited State ◽  
Colonial Form ◽  
The Common ◽  
Eighteenth And Nineteenth Centuries ◽  
Catalyzed Oxidation

The phenomenon of bioluminescence has fascinated layman and scientist alike for many centuries. During the eighteenth and nineteenth centuries a number of observations were reported on the physiology of bioluminescence in Renilla, the common sea pansy. More recently biochemists have directed their attention to the molecular basis of luminosity in this colonial form. These studies have centered primarily on defining the chemical basis for bioluminescence and its control. It is now established that bioluminescence in Renilla arises due to the luciferase-catalyzed oxidation of luciferin. This results in the creation of a product (oxyluciferin) in an electronic excited state. The transition of oxyluciferin from its excited state to the ground state leads to light emission.

Torus Circumference and Thickness Parameters From a Linear DNA Size Series Suggest How Toruses Self-Assemble

1985 ◽  
Vol 43 ◽  
pp. 522-523
Author(s):  
George C. Ruben ◽  
Kenneth A. Marx
Keyword(s):  
Tertiary Structure ◽  
Dna Complexes ◽  
Tertiary Structures ◽  
Self Assembling ◽  
Double Stranded Dna ◽  
Calf Thymus ◽  
Dna Organization ◽  
Condensed Dna ◽  
Dna Size

Certain double stranded DNA bacteriophage and viruses are thought to have their DNA organized into large torus shaped structures. Morphologically, these poorly understood biological DNA tertiary structures resemble spermidine-condensed DNA complexes formed in vitro in the total absence of other macromolecules normally synthesized by the pathogens for the purpose of their own DNA packaging. Therefore, we have studied the tertiary structure of these self-assembling torus shaped spermidine- DNA complexes in a series of reports. Using freeze-etch, low Pt-C metal (10-15Å) replicas, we have visualized the microscopic DNA organization of both calf Thymus( CT) and linear 0X-174 RFII DNA toruses. In these structures DNA is circumferentially wound, continuously, around the torus into a semi-crystalline, hexagonal packed array of parallel DNA helix sections.

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