Mg2+-FreeBacillus stearothermophilusTryptophanyl-tRNA Synthetase Retains a Major Fraction of the Overall Rate Enhancement for Tryptophan Activation

Violetta Weinreb; Charles W. Carter

doi:10.1021/ja076557x

Mg2+-FreeBacillus stearothermophilusTryptophanyl-tRNA Synthetase Retains a Major Fraction of the Overall Rate Enhancement for Tryptophan Activation

Journal of the American Chemical Society ◽

10.1021/ja076557x ◽

2008 ◽

Vol 130 (4) ◽

pp. 1488-1494 ◽

Cited By ~ 12

Author(s):

Violetta Weinreb ◽

Charles W. Carter

Keyword(s):

Trna Synthetase ◽

Major Fraction ◽

Rate Enhancement

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An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures

ACS Chemical Biology ◽

10.1021/acschembio.5b01011 ◽

2016 ◽

Vol 11 (6) ◽

pp. 1661-1668 ◽

Cited By ~ 9

Author(s):

Paul J. Sapienza ◽

Li Li ◽

Tishan Williams ◽

Andrew L. Lee ◽

Charles W. Carter

Keyword(s):

Ground State ◽

Trna Synthetase ◽

Tertiary Structures ◽

Rate Enhancement ◽

Catalytic Rate

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Orphan designation: 505 amino acid protein, corresponding to amino acids 2-506 of the wild-type human histidyl-tRNA synthetase, Treatment of limb-girdle muscular dystrophy

Case Medical Research ◽

10.31525/cmr-2935ce2 ◽

2020 ◽

Author(s):

Keyword(s):

Amino Acids ◽

Amino Acid ◽

Muscular Dystrophy ◽

Trna Synthetase ◽

Limb Girdle Muscular Dystrophy ◽

Wild Type ◽

Orphan Designation ◽

Acid Protein ◽

Amino Acid Protein

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Faculty Opinions recommendation of An aminoacyl tRNA synthetase whose sequence fits into neither of the two known classes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000088.1101 ◽

2001 ◽

Author(s):

Anne-Catherine Dock-Bregeon

Keyword(s):

Trna Synthetase ◽

Aminoacyl Trna Synthetase

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Faculty Opinions recommendation of A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000366.1351 ◽

2001 ◽

Author(s):

Anne-Catherine Dock-Bregeon

Keyword(s):

Escherichia Coli ◽

Trna Synthetase

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Faculty Opinions recommendation of The roles of coenzyme A in the pyruvate:ferredoxin oxidoreductase reaction mechanism: rate enhancement of electron transfer from a radical intermediate to an iron-sulfur cluster.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002479.109611 ◽

2002 ◽

Author(s):

Wolfgang Buckel

Keyword(s):

Electron Transfer ◽

Reaction Mechanism ◽

Coenzyme A ◽

Radical Intermediate ◽

Iron Sulfur Cluster ◽

Rate Enhancement ◽

Sulfur Cluster ◽

Iron Sulfur ◽

Pyruvate:Ferredoxin Oxidoreductase

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Faculty Opinions recommendation of Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli leucyl-tRNA synthetase in editing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009103.118807 ◽

2002 ◽

Author(s):

Anne-Catherine Dock-Bregeon

Keyword(s):

Escherichia Coli ◽

Trna Synthetase

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Faculty Opinions recommendation of Crystal structure of a human aminoacyl-tRNA synthetase cytokine.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1010763.176313 ◽

2002 ◽

Author(s):

John Perona

Keyword(s):

Crystal Structure ◽

Trna Synthetase ◽

Aminoacyl Trna Synthetase

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Faculty Opinions recommendation of An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047563.497530 ◽

2006 ◽

Cited By ~ 1

Author(s):

Brian Popko

Keyword(s):

Mouse Model ◽

Trna Synthetase ◽

Dominant Mutation ◽

Charcot Marie Tooth

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Faculty Opinions recommendation of Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1159143.619443 ◽

2009 ◽

Author(s):

Pascale Legault

Keyword(s):

Molecular Basis ◽

Trna Synthetase

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Faculty Opinions recommendation of Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12193961.13360056 ◽

2011 ◽

Author(s):

Nereo Bresolin ◽

Dario Ronchi

Keyword(s):

Exome Sequencing ◽

Trna Synthetase ◽

Mitochondrial Cardiomyopathy

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