scholarly journals Development of a Cyclic Peptide Inhibitor of the p6/UEV Protein–Protein Interaction

2019 ◽  
Vol 14 (9) ◽  
pp. 1874-1878 ◽  
Author(s):  
Katherine R. Lennard ◽  
Reece M. Gardner ◽  
Cyrielle Doigneaux ◽  
Francisco Castillo ◽  
Ali Tavassoli
Keyword(s):  
Protein Interaction ◽  
Cyclic Peptide ◽  
Peptide Inhibitor ◽  
Protein Protein Interaction

scholarly journals A Cyclic Peptide Inhibitor of the iNOS–SPSB Protein–Protein Interaction as a Potential Anti-Infective Agent

2018 ◽  
Vol 13 (10) ◽  
pp. 2930-2938 ◽  
Author(s):  
Maiada M. Sadek ◽  
Nicholas Barlow ◽  
Eleanor W. W. Leung ◽  
Billy J. Williams-Noonan ◽  
Beow Keat Yap ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Cyclic Peptide ◽  
Peptide Inhibitor ◽  
Protein Protein Interaction ◽  
Infective Agent

Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction

2020 ◽  
Vol 28 (21) ◽  
pp. 115738
Author(s):  
Stefania Colarusso ◽  
Daniele De Simone ◽  
Tommaso Frattarelli ◽  
Matteo Andreini ◽  
Mauro Cerretani ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Cyclic Peptide ◽  
Peptide Inhibitors ◽  
Protein Protein Interaction ◽  
Nrf2 Protein

scholarly journals Rational design of a potent macrocyclic peptide inhibitor targeting the PD-1/PD-L1 protein–protein interaction

RSC Advances ◽  
2021 ◽  
Vol 11 (38) ◽  
pp. 23270-23279
Author(s):  
Qi Miao ◽  
Wanheng Zhang ◽  
Kuojun Zhang ◽  
He Li ◽  
Jidong Zhu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Protein Interaction ◽  
Rational Design ◽  
Peptide Inhibitor ◽  
Protein Protein Interaction ◽  
Comparable Activity ◽  
L1 Protein ◽  
Macrocyclic Peptide

The co-crystal structure and CADD-guided rational design of JMPDP-027 which has comparable activity to mAb in both in vitro and in vivo tests.

Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency

2018 ◽  
Vol 143 ◽  
pp. 1578-1589 ◽  
Author(s):  
Meng-Chen Lu ◽  
Qiong Jiao ◽  
Tian Liu ◽  
Shi-Jie Tan ◽  
Hai-Shan Zhou ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Cyclic Peptide ◽  
High Cell ◽  
Protein Protein Interaction ◽  
Nrf2 Protein

Protein–protein interaction and in silico mutagenesis studies on IL17A and its peptide inhibitor

3 Biotech ◽  
2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Aishwarya Kochhar ◽  
Noor Saba Khan ◽  
Ravi Deval ◽  
Dibyabhaba Pradhan ◽  
Lingaraja Jena ◽  
...  
Keyword(s):  
Protein Interaction ◽  
In Silico ◽  
Peptide Inhibitor ◽  
Protein Protein Interaction
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