Binding Characterization of Agonists and Antagonists by MCCS: A Case Study from Adenosine A2A Receptor

2021 ◽  
Author(s):  
Jin Cheng ◽  
Maozi Chen ◽  
Siyi Wang ◽  
Tianjian Liang ◽  
Hui Chen ◽  
...  
Keyword(s):  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a

scholarly journals Characterization of the trigeminovascular actions of several adenosine A2A receptor antagonists in an in vivo rat model of migraine

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Kristian A. Haanes ◽  
Alejandro Labastida-Ramírez ◽  
Kayi Y. Chan ◽  
René de Vries ◽  
Brian Shook ◽  
...  
Keyword(s):  
Rat Model ◽  
Adenosine A2a Receptor ◽  
Receptor Antagonists ◽  
Adenosine A2a Receptor Antagonists ◽  
A2a Receptor ◽  
Adenosine A2a

Characterization of [3H]ZM 241385 binding in wild-type and adenosine A2A receptor knockout mice

2004 ◽  
Vol 504 (1-2) ◽  
pp. 55-59 ◽  
Author(s):  
Mary Kelly ◽  
Alexis Bailey ◽  
Catherine Ledent ◽  
Ian Kitchen ◽  
Susanna Hourani
Keyword(s):  
Knockout Mice ◽  
Adenosine A2a Receptor ◽  
Wild Type ◽  
A2a Receptor ◽  
Adenosine A2a

Further characterization of a CNS adenosine A2a receptor ligand [11C]KF18446 within vitro autoradiography andin vivo tissue uptake

2000 ◽  
Vol 14 (2) ◽  
pp. 81-89 ◽  
Author(s):  
Kiichi Ishiwata ◽  
Nobuo Ogi ◽  
Junichi Shimada ◽  
Hiromi Nonaka ◽  
Akira Tanaka ◽  
...  
Keyword(s):  
Adenosine A2a Receptor ◽  
Tissue Uptake ◽  
Receptor Ligand ◽  
A2a Receptor ◽  
Adenosine A2a

Stabilised G protein-coupled receptors in structure-based drug design: a case study with adenosine A2A receptor

MedChemComm ◽  
2013 ◽  
Vol 4 (1) ◽  
pp. 52-67 ◽  
Author(s):  
Stephen P. Andrews ◽  
Benjamin Tehan
Keyword(s):  
Parkinson’S Disease ◽  
Drug Design ◽  
G Protein ◽  
G Protein Coupled Receptors ◽  
Adenosine A2a Receptor ◽  
Structure Based Drug Design ◽  
A2a Receptor ◽  
Adenosine A2a ◽  
G Protein Coupled

The first example of structure-based drug design with stabilised GPCRs has enabled the identification of a preclinical candidate for the treatment of Parkinson's disease.

Behavioural and neurochemical characterization of the adenosine A2A receptor antagonist ST1535

2008 ◽  
Vol 579 (1-3) ◽  
pp. 149-152 ◽  
Author(s):  
Mariangela Galluzzo ◽  
Anita Pintor ◽  
Antonella Pèzzola ◽  
Rosa Grieco ◽  
Franco Borsini ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a Receptor Antagonist ◽  
Adenosine A2a

Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analyses

2004 ◽  
Vol 1000 (1-2) ◽  
pp. 156-173 ◽  
Author(s):  
Liqun Yu ◽  
Martin C. Frith ◽  
Yutaka Suzuki ◽  
Robert A. Peterfreund ◽  
Tom Gearan ◽  
...  
Keyword(s):  
Genomic Organization ◽  
Receptor Gene ◽  
Adenosine A2a Receptor ◽  
Bioinformatics Analyses ◽  
A2a Receptor ◽  
Adenosine A2a
Sign in / Sign up

Export Citation Format

Share Document