Synthesis and Characterization of a Dual Kappa-Delta Opioid Receptor Agonist Analgesic Blocking Cocaine Reward Behavior

András Váradi; Gina F. Marrone; Shainnel O. Eans; Michelle L. Ganno; Joan J. Subrath; Valerie Le Rouzic; Amanda Hunkele; Gavril W. Pasternak; Jay P. McLaughlin; Susruta Majumdar

doi:10.1021/acschemneuro.5b00153

Synthesis and Characterization of a Dual Kappa-Delta Opioid Receptor Agonist Analgesic Blocking Cocaine Reward Behavior

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.5b00153 ◽

2015 ◽

Vol 6 (11) ◽

pp. 1813-1824 ◽

Cited By ~ 20

Author(s):

András Váradi ◽

Gina F. Marrone ◽

Shainnel O. Eans ◽

Michelle L. Ganno ◽

Joan J. Subrath ◽

...

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Synthesis And Characterization ◽

Delta Opioid Receptor ◽

Opioid Receptor Agonist ◽

Cocaine Reward

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Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide cyclo[Pro-Sar-Phe-d-Phe]: A Mixed Opioid Receptor Agonist–Antagonist Following Oral Administration

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00086 ◽

2020 ◽

Vol 11 (9) ◽

pp. 1324-1336 ◽

Cited By ~ 1

Author(s):

Michael J. Ferracane ◽

Ariana C. Brice-Tutt ◽

Jeremy S. Coleman ◽

Grant G. Simpson ◽

Lisa L. Wilson ◽

...

Keyword(s):

Oral Administration ◽

Opioid Receptor ◽

Receptor Agonist ◽

Synthesis And Characterization ◽

Design Synthesis ◽

Opioid Receptor Agonist

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Synthesis and characterization of biotinylated and desbiotinylated analogues of DALDA, μ-opioid receptor agonist.

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)51467-6 ◽

1993 ◽

Vol 61 ◽

pp. 142

Author(s):

Shizuo Yamada ◽

Ulrich Bickel ◽

William M. Pardridge

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Synthesis And Characterization ◽

Opioid Receptor Agonist ◽

Μ Opioid Receptor

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Characterization of the discriminative stimulus effects of the delta‐opioid receptor agonist, SNC80, in rats

The FASEB Journal ◽

10.1096/fasebj.2018.32.1_supplement.822.4 ◽

2018 ◽

Vol 32 (S1) ◽

Author(s):

Ashleigh L. Matthews ◽

Kenner C. Rice ◽

Emily M. Jutkiewicz

Keyword(s):

Opioid Receptor ◽

Discriminative Stimulus ◽

Receptor Agonist ◽

Delta Opioid Receptor ◽

Discriminative Stimulus Effects ◽

Opioid Receptor Agonist ◽

Stimulus Effects

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Characterization of Delta Opioid Receptor Activity of MMP2200, a Mixed Efficacy Mu and Delta Opioid Receptor Agonist

The FASEB Journal ◽

10.1096/fasebj.2020.34.s1.05714 ◽

2020 ◽

Vol 34 (S1) ◽

pp. 1-1

Author(s):

Gwendolyn Erin Burgess ◽

Robin Polt ◽

Kenner C. Rice ◽

Emily M. Jutkiewicz

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Receptor Activity ◽

Delta Opioid Receptor ◽

Opioid Receptor Agonist ◽

Mixed Efficacy

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Faculty Opinions recommendation of Absence of conditioned place preference or reinstatement with bivalent ligands containing mu-opioid receptor agonist and delta-opioid receptor antagonist pharmacophores.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1086845.539776 ◽

2007 ◽

Author(s):

Howard Fields

Keyword(s):

Receptor Antagonist ◽

Conditioned Place Preference ◽

Opioid Receptor ◽

Receptor Agonist ◽

Mu Opioid Receptor ◽

Place Preference ◽

Delta Opioid Receptor ◽

Bivalent Ligands ◽

Mu Opioid ◽

Opioid Receptor Agonist

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Delta opioid receptor agonist BW373U86 attenuates post-resuscitation brain injury in a rat model of asphyxial cardiac arrest

Resuscitation ◽

10.1016/j.resuscitation.2013.10.022 ◽

2014 ◽

Vol 85 (2) ◽

pp. 299-305 ◽

Cited By ~ 7

Author(s):

Lu Yang ◽

Xiaoyong Zhao ◽

Meiyan Sun ◽

Xude Sun ◽

Linong Yao ◽

...

Keyword(s):

Cardiac Arrest ◽

Brain Injury ◽

Opioid Receptor ◽

Rat Model ◽

Receptor Agonist ◽

Delta Opioid Receptor ◽

Opioid Receptor Agonist ◽

Asphyxial Cardiac Arrest

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Conformationally constrained cyclic enkephalin analogs with pronounced delta opioid receptor agonist selectivity

Life Sciences ◽

10.1016/0024-3205(83)90239-4 ◽

1983 ◽

Vol 32 (22) ◽

pp. 2565-2569 ◽

Cited By ~ 84

Author(s):

Henry I. Mosberg ◽

Robin Hurst ◽

Victor J. Hruby ◽

James J. Galligan ◽

Thomas F. Burks ◽

...

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Delta Opioid Receptor ◽

Conformationally Constrained ◽

Opioid Receptor Agonist

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Uptake and efflux of the peptidic delta-opioid receptor agonist [D-penicillamine2,5]-enkephalin at the murine blood–brain barrier by in situ perfusion

Neuroscience Letters ◽

10.1016/s0304-3940(01)01640-8 ◽

2001 ◽

Vol 301 (3) ◽

pp. 155-158 ◽

Cited By ~ 52

Author(s):

Claude Dagenais ◽

Julie Ducharme ◽

Gary M. Pollack

Keyword(s):

Blood Brain Barrier ◽

Opioid Receptor ◽

Receptor Agonist ◽

Brain Barrier ◽

Delta Opioid Receptor ◽

In Situ Perfusion ◽

Blood Brain ◽

Opioid Receptor Agonist

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The central antidepressant‐like and antinociceptive effects of a delta opioid receptor agonist SNC80 in rats

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.581.3 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Chang‐Ming Chen ◽

Chia‐Chen Cheng ◽

Pin‐Yen Su ◽

Mei‐Chuan Ko

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Delta Opioid Receptor ◽

Opioid Receptor Agonist ◽

Antinociceptive Effects

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The antinociceptive effects of a dual kappa-delta opioid receptor agonist in the mouse formalin test

Behavioural Pharmacology ◽

10.1097/fbp.0000000000000541 ◽

2020 ◽

Vol 31 (2&3) ◽

pp. 174-178 ◽

Cited By ~ 2

Author(s):

Esad Ulker ◽

Wisam Toma ◽

Alyssa White ◽

Rajendra Uprety ◽

Susruta Majumdar ◽

...

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Formalin Test ◽

Delta Opioid Receptor ◽

Opioid Receptor Agonist ◽

Antinociceptive Effects

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