Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors

Correction to Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors

ACS Medicinal Chemistry Letters ◽

10.1021/acsmedchemlett.9b00336 ◽

2019 ◽

Vol 10 (9) ◽

pp. 1358-1358 ◽

Cited By ~ 1

Author(s):

Taha Y. Taha ◽

Shaimaa M. Aboukhatwa ◽

Rachel C. Knopp ◽

Naohiko Ikegaki ◽

Hazem Abdelkarim ◽

...

Keyword(s):

Histone Deacetylase ◽

Biological Evaluation ◽

Selective Inhibitors ◽

Design Synthesis ◽

Histone Deacetylase 8 ◽

Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motif

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.08.029 ◽

2018 ◽

Vol 26 (8) ◽

pp. 1418-1425 ◽

Cited By ~ 6

Author(s):

Jinyu Yang ◽

Gaoliang Cheng ◽

Qihao Xu ◽

Shenglin Luan ◽

Shuxiang Wang ◽

...

Keyword(s):

Histone Deacetylase ◽

Hydroxamic Acid ◽

Biological Evaluation ◽

Histone Deacetylase 6 ◽

Selective Inhibitors ◽

Design Synthesis ◽

Recognition Motif ◽

Surface Recognition ◽

Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-β-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.10.073 ◽

2012 ◽

Vol 20 (1) ◽

pp. 356-367 ◽

Cited By ~ 8

Author(s):

Daisuke Minehira ◽

Daisuke Takeda ◽

Hirokazu Urata ◽

Atsushi Kato ◽

Isao Adachi ◽

...

Keyword(s):

Biological Evaluation ◽

Selective Inhibitors ◽

Design Synthesis ◽

Acetic Acids

Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation

ACS Omega ◽

10.1021/acsomega.0c05870 ◽

2021 ◽

Vol 6 (7) ◽

pp. 4907-4920

Author(s):

Duong T. Anh ◽

Pham-The Hai ◽

Le D. Huy ◽

Hoang B. Ngoc ◽

Trinh T. M. Ngoc ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.03.005 ◽

2019 ◽

Vol 170 ◽

pp. 112-125 ◽

Cited By ~ 3

Author(s):

Xiaodong Ma ◽

Jun Wei ◽

Chang Wang ◽

Dongyan Gu ◽

Yongzhou Hu ◽

...

Keyword(s):

B Cell ◽

Biological Evaluation ◽

Selective Inhibitors ◽

Design Synthesis ◽

Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.01.021 ◽

2018 ◽

Vol 146 ◽

pp. 79-92 ◽

Cited By ~ 14

Author(s):

Alshimaa M.A. Aboeldahab ◽

Eman A.M. Beshr ◽

Mai E. Shoman ◽

Safwat M. Rabea ◽

Omar M. Aly

Keyword(s):

Histone Deacetylase ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103137 ◽

2019 ◽

Vol 91 ◽

pp. 103137 ◽

Cited By ~ 5

Author(s):

Pervaiz Ali Channar ◽

Hina Irum ◽

Abid Mahmood ◽

Ghulam Shabir ◽

Sumera Zaib ◽

...

Keyword(s):

Alkaline Phosphatase ◽

Biological Evaluation ◽

Selective Inhibitors ◽

Design Synthesis ◽

Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: Selective inhibitors of lysosomal sialidase (NEU1)

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2007.11.084 ◽

2008 ◽

Vol 18 (2) ◽

pp. 532-537 ◽

Cited By ~ 41

Author(s):

Sadagopan Magesh ◽

Setsuko Moriya ◽

Tohru Suzuki ◽

Taeko Miyagi ◽

Hideharu Ishida ◽

...

Keyword(s):

Biological Evaluation ◽

Selective Inhibitors ◽

Design Synthesis ◽

Lysosomal Sialidase

Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer’s Disease

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.7b00345 ◽

2017 ◽

Vol 9 (2) ◽

pp. 328-345 ◽

Cited By ~ 21

Author(s):

Fei Mao ◽

Huan Wang ◽

Wei Ni ◽

Xinyu Zheng ◽

Manjiong Wang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

First Generation ◽

Biological Evaluation ◽

Selective Inhibitors ◽

Design Synthesis ◽

Phosphodiesterase 5 ◽

Dual Target

Design, synthesis and biological evaluation of 2-amino-N-(2-aminophenyl)thiazole-5-carboxamide derivatives as novel Bcr-Abl and histone deacetylase dual inhibitors

RSC Advances ◽

10.1039/c6ra21271a ◽

2016 ◽

Vol 6 (105) ◽

pp. 103178-103184 ◽

Cited By ~ 11

Author(s):

Xin Chen ◽

Shuang Zhao ◽

Yichao Wu ◽

Yadong Chen ◽

Tao Lu ◽

...

Keyword(s):

Histone Deacetylase ◽

Inhibitory Activity ◽

Biological Evaluation ◽

Design Approach ◽

Design Synthesis ◽

Dual Inhibitors ◽

Novel Design

A novel design approach: combination of Bcr-Abl and HDAC inhibitory activity in one molecule to produce dual inhibitors.