Graft Copolymer-Templated Mesoporous TiO2 Films Micropatterned with Poly(ethylene glycol) Hydrogel: Novel Platform for Highly Sensitive Protein Microarrays

2011 ◽  
Vol 3 (2) ◽  
pp. 573-581 ◽  
Author(s):  
Kyung Jin Son ◽  
Sung Hoon Ahn ◽  
Jong Hak Kim ◽  
Won-Gun Koh
Keyword(s):  
Ethylene Glycol ◽  
Graft Copolymer ◽  
Protein Microarrays ◽  
Mesoporous Tio2 ◽  
Tio2 Films ◽  
Poly Ethylene Glycol ◽  
Highly Sensitive ◽  
Mesoporous Tio2 Films ◽  
Poly Ethylene

Construction of semi-fluorinated amphiphilic graft copolymer bearing a poly(2-methyl-1,4-bistrifluorovinyloxybenzene) backbone and poly(ethylene glycol) side chains via the grafting-onto strategy

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 39668-39676 ◽  
Author(s):  
Guolin Lu ◽  
Hao Liu ◽  
Haifeng Gao ◽  
Chun Feng ◽  
Yongjun Li ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Graft Copolymer ◽  
Graft Copolymers ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Amphiphilic Graft Copolymer ◽  
Amphiphilic Graft Copolymers ◽  
Poly Ethylene ◽  
Williamson Reaction ◽  
Grafting Onto

Amphiphilic graft copolymers bearing a hydrophobic PMBTFVB backbone and hydrophilic PEG side chains were synthesized by Williamson reaction through the grafting-onto strategy.

Synthesis of curdlan-graft-poly(ethylene glycol) and formulation of doxorubicin-loaded core–shell nanoparticles

2012 ◽  
Vol 27 (1) ◽  
pp. 3-17 ◽  
Author(s):  
Benjamin C. Lehtovaara ◽  
Mohit S. Verma ◽  
Frank X. Gu
Keyword(s):  
Ethylene Glycol ◽  
Graft Copolymer ◽  
Fickian Diffusion ◽  
High Yield ◽  
Core Shell ◽  
Hydroxyl Groups ◽  
Poly Ethylene Glycol ◽  
Shell Nanoparticles ◽  
Hemolysis Assay ◽  
Poly Ethylene

A new core–shell nanoparticle containing the chemotherapeutic drug doxorubicin was formulated via amphiphilic graft copolymer self-assembly using curdlan- graft-poly(ethylene glycol) (curdlan -g-PEG). The graft copolymer was synthesized through the dicyclohexylcarbodiimide ester linkage of carboxylated PEG to the hydroxyl groups of the curdlan backbone. The nanoparticles were 109.9 nm in size and encapsulated doxorubicin in high yield (4%–5% wt/wt). The nanoparticles also controlled the release of doxorubicin over 24 h with a release profile that followed a Fickian diffusion model. The biocompatibility of curdlan- g-PEG was confirmed by hemolysis assay. This is the first nanoparticle formulated using the hydrophobicity of curdlan for concealing the immunomodulatory potential of curdlan within the core.

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