Passivated Aluminum Nanohole Arrays for Label-Free Biosensing Applications

2013 ◽  
Vol 6 (2) ◽  
pp. 1005-1010 ◽  
Author(s):  
Víctor Canalejas-Tejero ◽  
Sonia Herranz ◽  
Alyssa Bellingham ◽  
María Cruz Moreno-Bondi ◽  
Carlos Angulo Barrios
Keyword(s):  
Label Free ◽  
Nanohole Arrays

scholarly journals Metallic Nanohole Arrays on Fluoropolymer Substrates as Small Label-Free Real-Time Bioprobes

Nano Letters ◽  
2008 ◽  
Vol 8 (9) ◽  
pp. 2718-2724 ◽  
Author(s):  
Jiun-Chan Yang ◽  
Jin Ji ◽  
James M. Hogle ◽  
Dale N. Larson
Keyword(s):  
Real Time ◽  
Label Free ◽  
Nanohole Arrays

Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment

2009 ◽  
Author(s):  
A. Lesuffleur ◽  
Kwan Seop Lim ◽  
N.C. Lindquist ◽  
Hyungsoon Im ◽  
A.E. Warrington ◽  
...  
Keyword(s):  
Lipid Membrane ◽  
Label Free ◽  
Nanohole Arrays

Biosensing using plasmonic nanohole arrays with small, homogenous and tunable aperture diameters

The Analyst ◽  
2016 ◽  
Vol 141 (12) ◽  
pp. 3803-3810 ◽  
Author(s):  
Kunli Xiong ◽  
Gustav Emilsson ◽  
Andreas B. Dahlin
Keyword(s):  
Molecular Detection ◽  
Label Free ◽  
Nanohole Arrays

Plasmonic nanohole arrays are widely used for optical label-free molecular detection.

scholarly journals Real-Time Label-Free Surface Plasmon Resonance Biosensing with Gold Nanohole Arrays Fabricated by Nanoimprint Lithography

Sensors ◽  
2013 ◽  
Vol 13 (10) ◽  
pp. 13960-13968 ◽  
Author(s):  
Josu Martinez-Perdiguero ◽  
Aritz Retolaza ◽  
Deitze Otaduy ◽  
Aritz Juarros ◽  
Santos Merino
Keyword(s):  
Free Surface ◽  
Surface Plasmon Resonance ◽  
Real Time ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Nanoimprint Lithography ◽  
Label Free ◽  
Nanohole Arrays

scholarly journals Rayleigh anomaly-enabled mode hybridization in gold nanohole arrays by scalable colloidal lithography for highly-sensitive biosensing

Nanophotonics ◽  
2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Zhiliang Zhang ◽  
Feng Zhao ◽  
Renxian Gao ◽  
Chih-Yu Jao ◽  
Churong Ma ◽  
...  
Keyword(s):  
Refractive Index ◽  
Plasmonic Nanostructures ◽  
Label Free ◽  
Colloidal Lithography ◽  
Large Area ◽  
Nanohole Array ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Nanohole Arrays ◽  
Rayleigh Anomaly

Abstract Plasmonic sensors exhibit tremendous potential to accomplish real-time, label-free, and high-sensitivity biosensing. Gold nanohole array (GNA) is one of the classic plasmonic nanostructures that can be readily fabricated and integrated into microfluidic platforms for a variety of applications. Even though GNA has been widely studied, new phenomena and applications are still emerging continuously expanding its capabilities. In this article, we demonstrated narrow-band high-order resonances enabled by Rayleigh anomaly in the nanohole arrays that are fabricated by scalable colloidal lithography. We fabricated large-area GNAs with different hole diameters, and investigated their transmission characteristics both numerically and experimentally. We showed that mode hybridization between the plasmon mode of the nanoholes and Rayleigh anomaly of the array could give rise to high-quality decapole resonance with a unique nearfield profile. We experimentally achieved a refractive index sensitivity, i.e., RIS up to 407 nm/RIU. More importantly, we introduced a spectrometer-free refractive index sensing based on lens-free smartphone imaging of GNAs with (intensity) sensitivity up to 137%/RIU. Using this platform, we realized the label-free detection of BSA molecules with concentration as low as 10−8 M. We believe our work could pave the way for highly sensitive and compact point-of-care devices with cost-effective and high-throughput plasmonic chips.

Aluminum Nanohole Arrays Fabricated on Polycarbonate for Compact Disc-Based Label-Free Optical Biosensing

Plasmonics ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. 645-649 ◽  
Author(s):  
C. A. Barrios ◽  
V. Canalejas-Tejero ◽  
S. Herranz ◽  
M. C. Moreno-Bondi ◽  
M. Avella-Oliver ◽  
...  
Keyword(s):  
Compact Disc ◽  
Label Free ◽  
Optical Biosensing ◽  
Nanohole Arrays

Chiral nanohole arrays

Nanoscale ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 2479-2491 ◽  
Author(s):  
Bin Ai ◽  
Hoang M. Luong ◽  
Yiping Zhao
Keyword(s):  
Label Free ◽  
Nanohole Array ◽  
Drug Molecules ◽  
Nanohole Arrays

Ultra-thin chiral nanohole array films are fabricated by a simple and efficient shadow sphere lithography (SSL) method and achieve label-free enantiodiscrimination of biomolecules and drug molecules at the picogram level.

Plasmonic Nanohole Arrays on a Robust Hybrid Substrate for Highly Sensitive Label-Free Biosensing

ACS Photonics ◽  
2015 ◽  
Vol 2 (8) ◽  
pp. 1167-1174 ◽  
Author(s):  
Arif E. Cetin ◽  
Dordaneh Etezadi ◽  
Betty C. Galarreta ◽  
Mickael P. Busson ◽  
Yasa Eksioglu ◽  
...  
Keyword(s):  
Label Free ◽  
Highly Sensitive ◽  
Nanohole Arrays

scholarly journals Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples

2016 ◽  
Vol 7 ◽  
pp. 1564-1573 ◽  
Author(s):  
Christa Genslein ◽  
Peter Hausler ◽  
Eva-Maria Kirchner ◽  
Rudolf Bierl ◽  
Antje J Baeumner ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Limit Of Detection ◽  
Binding Capacity ◽  
Gold Films ◽  
Label Free ◽  
Sensor Surface ◽  
Nanohole Array ◽  
Reduced Graphene ◽  
Nanohole Arrays

The label-free nature of surface plasmon resonance techniques (SPR) enables a fast, specific, and sensitive analysis of molecular interactions. However, detection of highly diluted concentrations and small molecules is still challenging. It is shown here that in contrast to continuous gold films, gold nanohole arrays can significantly improve the performance of SPR devices in angle-dependent measurement mode, as a signal amplification arises from localized surface plasmons at the nanostructures. This leads consequently to an increased sensing capability of molecules bound to the nanohole array surface. Furthermore, a reduced graphene oxide (rGO) sensor surface was layered over the nanohole array. Reduced graphene oxide is a 2D nanomaterial consisting of sp2-hybridized carbon atoms and is an attractive receptor surface for SPR as it omits any bulk phase and therefore allows fast response times. In fact, it was found that nanohole arrays demonstrated a higher shift in the resonance angle of 250–380% compared to a continuous gold film. At the same time the nanohole array structure as characterized by its diameter-to-periodicity ratio had minimal influence on the binding capacity of the sensor surface. As a simple and environmentally highly relevant model, binding of the plasticizer diethyl phthalate (DEP) via π-stacking was monitored on the rGO gold nanohole array realizing a limit of detection of as low as 20 nM. The concentration-dependent signal change was studied with the best performing rGO-modified nanohole arrays. Compared to continuous gold films a diameter-to-periodicity ratio (D/P) of 0.43 lead to a 12-fold signal enhancement. Finally, the effect of environmental waters on the sensor was evaluated using samples from sea, lake and river waters spiked with analytically relevant amounts of DEP during which significant changes in the SPR signal are observed. It is expected that this concept can be successfully transferred to enhance the sensitivity in SPR sensors.

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