Comparison of the membrane-bound states of two structurally similar .vdelta.-selective opioid peptides by transferred nuclear Overhauser effect spectroscopy and molecular modeling

Biochemistry ◽  
1993 ◽  
Vol 32 (48) ◽  
pp. 13180-13189 ◽  
Author(s):  
Terry O. Matsunaga ◽  
Nathan Collins ◽  
Varadarajan Ramaswami ◽  
Susan H. Yamamura ◽  
David F. O'Brien ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Opioid Peptides ◽  
Bound States ◽  
Nuclear Overhauser Effect ◽  
Overhauser Effect ◽  
Membrane Bound ◽  
Nuclear Overhauser

Comparison of the membrane-bound states of two structurally similar .delta.-selective opioid peptides by transferred nuclear Overhauser effect spectroscopy and molecular modeling. [Erratum to document cited in CA119(25):262678y]

Biochemistry ◽  
1994 ◽  
Vol 33 (17) ◽  
pp. 5356-5356
Author(s):  
Terry O. Matsunaga ◽  
Nathan Collins ◽  
Varadarajan Ramaswami ◽  
Susan H. Yamamura ◽  
David F. O'Brien ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Opioid Peptides ◽  
Bound States ◽  
Nuclear Overhauser Effect ◽  
Overhauser Effect ◽  
Membrane Bound ◽  
Nuclear Overhauser

Membrane-bound conformation of a signal peptide: A transferred nuclear Overhauser effect analysis

Biochemistry ◽  
1993 ◽  
Vol 32 (50) ◽  
pp. 13991-13999 ◽  
Author(s):  
Zhulun Wang ◽  
Jeffrey D. Jones ◽  
Josep Rizo ◽  
Lila M. Gierasch
Keyword(s):  
Signal Peptide ◽  
Nuclear Overhauser Effect ◽  
Effect Analysis ◽  
Overhauser Effect ◽  
Membrane Bound ◽  
Nuclear Overhauser

Describing Topology of Bound Ligand by Transferred Nuclear Overhauser Effect Spectroscopy and Molecular Modeling

2003 ◽  
pp. 417-434 ◽  
Author(s):  
Hans-Christian Siebert ◽  
Jesús Jiménez-Barbero ◽  
Sabine André ◽  
Herbert Kaltner ◽  
Hans-Joachim Gabius
Keyword(s):  
Molecular Modeling ◽  
Nuclear Overhauser Effect ◽  
Overhauser Effect ◽  
Nuclear Overhauser

Nuclear-magnetic-resonance studies on the conformation of membrane-bound alpha-mating factor. Transferred nuclear Overhauser effect analysis

1986 ◽  
Vol 154 (3) ◽  
pp. 607-615 ◽  
Author(s):  
Kaori WAKAMATSU ◽  
Akihiko OKADA ◽  
Midoriko SUZUKI ◽  
Tsutomu HIGASHIJIMA ◽  
Yoshihiro MASUI ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Nuclear Overhauser Effect ◽  
Effect Analysis ◽  
Magnetic Resonance Studies ◽  
Overhauser Effect ◽  
Membrane Bound ◽  
Nuclear Overhauser ◽  
Mating Factor ◽  
Nuclear Magnetic

1H NMR studies of [N-MeAib1, Tyr(Me)4]ANGII and [N-MeAib1, Tyr(Me)4, Ile8]ANGII in dimethylsulfoxide by nuclear Overhauser effect (NOE) enhancement spectroscopy: cis-trans Isomerism of the His-Pro bond

1990 ◽  
Vol 55 (4) ◽  
pp. 1106-1111 ◽  
Author(s):  
John Matsoukas ◽  
Paul Cordopatis ◽  
Raghav Yamdagni ◽  
Graham J. Moore
Keyword(s):  
1H Nmr ◽  
Nuclear Overhauser Effect ◽  
Nmr Studies ◽  
Restricted Rotation ◽  
Overhauser Effect ◽  
Major Isomer ◽  
Conformational Properties ◽  
Nuclear Overhauser

The conformational properties of the Sarmesin analogues [N-MeAib1, Tyr(Me)4]ANGII and [N-MeAib1, Tyr(Me)4, Ile8]ANGII in hexadeutero-dimethysulfoxide were investigated by Nuclear Overhauser Effect (NOE) Enhancement Studies. Cis-trans isomers (ratio 1 : 6) due to restricted rotation of the His-Pro bond were observed. Interresidue interactions between the His Cα proton and the two Pro Cδ protons revealed that the major isomer was the trans.

scholarly journals Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1080
Author(s):  
Imran Khan ◽  
Jing Peng ◽  
Zhuangjie Fang ◽  
Wei Liu ◽  
Wenjun Zhang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Nuclear Overhauser Effect ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Bioactive Natural Products ◽  
Chemical Structures ◽  
Overhauser Effect ◽  
Spectroscopic Analyses ◽  
Potential Resource ◽  
Nuclear Overhauser

The fungus strain SCSIO 40433 was isolated from an Arctic-derived glacier sediment sample and characterized as Tolypocladium cylindrosporum. A new compound, cylindromicin (1), and seven known secondary metabolites (2–8) were isolated from this strain. The chemical structures of these compounds were elucidated by comprehensive spectroscopic analyses. Cylindromicin (1) featured a 3,4-dihydro-2H-pyran skeleton. The absolute configuration of compound 1 was assigned via interpretation of key Nuclear Overhauser Effect Spectroscopy (NOESY) correlations and Electronic Circular Dichroism (ECD) calculation. Cylindromicin (1) exhibited significant tyrosinase inhibition activity. This study highlights Polar fungi as a potential resource for new bioactive natural products.

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