Cholesterol interactions with tetracosenoic acid phospholipids in model cell membranes: role of the double-bond position

Biochemistry ◽  
1990 ◽  
Vol 29 (14) ◽  
pp. 3466-3471 ◽  
Author(s):  
Eser Ayanoglu ◽  
Bich Huong Chiche ◽  
Mark Beatty ◽  
Carl Djerassi ◽  
Nejat Duzgunes

2016 ◽  
Vol 219 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaoran Wei ◽  
Xiaolei Qu ◽  
Lei Ding ◽  
Jingtian Hu ◽  
Wei Jiang


2019 ◽  
Vol 673 ◽  
pp. 414-423 ◽  
Author(s):  
Hanqiong Zhang ◽  
Xiaoran Wei ◽  
Ling Liu ◽  
Qingzhu Zhang ◽  
Wei Jiang


Langmuir ◽  
2012 ◽  
Vol 28 (47) ◽  
pp. 16318-16326 ◽  
Author(s):  
Babak Y. Moghadam ◽  
Wen-Che Hou ◽  
Charlie Corredor ◽  
Paul Westerhoff ◽  
Jonathan D. Posner


Langmuir ◽  
2015 ◽  
Vol 31 (15) ◽  
pp. 4473-4480 ◽  
Author(s):  
Fernanda F. Rossetti ◽  
Emanuel Schneck ◽  
Giovanna Fragneto ◽  
Oleg V. Konovalov ◽  
Motomu Tanaka


2016 ◽  
Vol 3 (1) ◽  
pp. 146-156 ◽  
Author(s):  
Xitong Liu ◽  
Kai Loon Chen

Adsorption of phosphate on chemical mechanical planarization nanoparticles can significantly impact the interactions between the nanoparticles and model cell membranes.





1996 ◽  
Vol 270 (1) ◽  
pp. C12-C30 ◽  
Author(s):  
A. S. Verkman ◽  
A. N. van Hoek ◽  
T. Ma ◽  
A. Frigeri ◽  
W. R. Skach ◽  
...  

This review summarizes recent progress in water-transporting mechanisms across cell membranes. Modern biophysical concepts of water transport and new measurement strategies are evaluated. A family of water-transporting proteins (water channels, aquaporins) has been identified, consisting of small hydrophobic proteins expressed widely in epithelial and nonepithelial tissues. The functional properties, genetics, and cellular distributions of these proteins are summarized. The majority of molecular-level information about water-transporting mechanisms comes from studies on CHIP28, a 28-kDa glycoprotein that forms tetramers in membranes; each monomer contains six putative helical domains surrounding a central aqueous pathway and functions independently as a water-selective channel. Only mutations in the vasopressin-sensitive water channel have been shown to cause human disease (non-X-linked congenital nephrogenic diabetes insipidus); the physiological significance of other water channels remains unproven. One mercurial-insensitive water channel has been identified, which has the unique feature of multiple overlapping transcriptional units. Systems for expression of water channel proteins are described, including Xenopus oocytes, mammalian and insect cells, and bacteria. Further work should be directed at elucidation of the role of water channels in normal physiology and disease, molecular analysis of regulatory mechanisms, and water channel structure determination at atomic resolution.



2010 ◽  
Vol 431 (1) ◽  
pp. 159-167 ◽  
Author(s):  
Natalia Fedulova ◽  
Françoise Raffalli-Mathieu ◽  
Bengt Mannervik

A primary role of GSTs (glutathione transferases) is detoxication of electrophilic compounds. In addition to this protective function, hGST (human GST) A3-3, a member of the Alpha class of soluble GSTs, has prominent steroid double-bond isomerase activity. The isomerase reaction is an obligatory step in the biosynthesis of steroid hormones, indicating a special role of hGST A3-3 in steroidogenic tissues. An analogous GST with high steroid isomerase activity has so far not been found in any other biological species. In the present study, we characterized a Sus scrofa (pig) enzyme, pGST A2-2, displaying high steroid isomerase activity. High levels of pGST A2-2 expression were found in ovary, testis and liver. In its functional properties, other than steroid isomerization, pGST A2-2 was most similar to hGST A3-3. The properties of the novel porcine enzyme lend support to the notion that particular GSTs play an important role in steroidogenesis.



Soft Matter ◽  
2012 ◽  
Vol 8 (20) ◽  
pp. 5501 ◽  
Author(s):  
Seunghwan Jeong ◽  
Sung Ho Ha ◽  
Sang-Hyun Han ◽  
Min-Cheol Lim ◽  
Sun Min Kim ◽  
...  


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