Spectroscopic Characterization of a DNA-Binding Domain, Zα, from the Editing Enzyme, dsRNA Adenosine Deaminase:  Evidence for Left-Handed Z-DNA in the Zα−DNA Complex†

Biochemistry ◽  
1998 ◽  
Vol 37 (38) ◽  
pp. 13313-13321 ◽  
Author(s):  
Imre Berger ◽  
William Winston ◽  
Ramasamy Manoharan ◽  
Thomas Schwartz ◽  
Jens Alfken ◽  
...  
Keyword(s):  
Dna Binding ◽  
Adenosine Deaminase ◽  
Spectroscopic Characterization ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
Left Handed ◽  
Z Dna ◽  
Editing Enzyme ◽  
Dna Complex

scholarly journals A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase

1997 ◽  
Vol 94 (16) ◽  
pp. 8421-8426 ◽  
Author(s):  
A. Herbert ◽  
J. Alfken ◽  
Y.-G. Kim ◽  
I. S. Mian ◽  
K. Nishikura ◽  
...  
Keyword(s):  
Dna Binding ◽  
Adenosine Deaminase ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
Double Stranded Rna ◽  
Z Dna ◽  
Editing Enzyme

scholarly journals Characterization of the Elk-1 ETS DNA-binding Domain

1995 ◽  
Vol 270 (11) ◽  
pp. 5805-5811 ◽  
Author(s):  
Paul Shore ◽  
Louise Bisset ◽  
Jeremy Lakey ◽  
Jonathan P. Waltho ◽  
Richard Virden ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Domain ◽  
Dna Binding Domain

Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1

1992 ◽  
Vol 12 (10) ◽  
pp. 4297-4304 ◽  
Author(s):  
D Ray ◽  
R Bosselut ◽  
J Ghysdael ◽  
M G Mattei ◽  
A Tavitian ◽  
...  
Keyword(s):  
Dna Binding ◽  
Cell Lines ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
New Gene ◽  
Carboxy Terminal Region ◽  
Carboxy Terminal ◽  
Hematopoietic Cell Lines

We have cloned a human cDNA from a new gene, spi-B, on the basis of its homology with the DNA-binding domain of the Spi-1/PU.1 putative oncogene product. spi-B codes for a protein of 262 amino acids presenting 43% overall identity with Spi-1. Its highly basic carboxy-terminal region exhibits 34% sequence identity with the DNA-binding domain of the Ets-1 protein. We showed that the Spi-B protein is able to bind the purine-rich sequence (PU box) recognized by Spi-1/PU.1 and to activate transcription of a reporter plasmid containing PU boxes. Chromosome in situ hybridization allowed us to map spi-B to the 19q13.3-19q13.4 region of the human genome. spi-B, like spi-1, was found to be expressed in various murine and human hematopoietic cell lines except T lymphoid cell lines.

Novel Interaction of the Z-DNA Binding Domain of Human ADAR1 with the Oncogenic c-Myc Promoter G-Quadruplex

2014 ◽  
Vol 426 (14) ◽  
pp. 2594-2604 ◽  
Author(s):  
Hyun-Jin Kang ◽  
Tuong Vy Thi Le ◽  
Kyungmin Kim ◽  
Jeonghwan Hur ◽  
Kyeong Kyu Kim ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
G Quadruplex ◽  
Z Dna

scholarly journals Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ)

2014 ◽  
Vol 42 (9) ◽  
pp. 5937-5948 ◽  
Author(s):  
Doyoun Kim ◽  
Jeonghwan Hur ◽  
Kwangsoo Park ◽  
Sangsu Bae ◽  
Donghyuk Shin ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Dna Binding ◽  
Binding Mode ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
Z Dna
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