Serum Amyloid A Protein Generates Preβ1 High-Density Lipoprotein from α-Migrating High-Density Lipoprotein†

Biochemistry ◽  
1999 ◽  
Vol 38 (51) ◽  
pp. 16958-16962 ◽  
Author(s):  
Takashi Miida ◽  
Toshiyuki Yamada ◽  
Toru Yamadera ◽  
Kazuyuki Ozaki ◽  
Koichi Inano ◽  
...  
1987 ◽  
Vol 242 (1) ◽  
pp. 301-303 ◽  
Author(s):  
M L Baltz ◽  
I F Rowe ◽  
D Caspi ◽  
W G Turnell ◽  
M B Pepys

Serum amyloid A protein (SAA) is an acute-phase apolipoprotein of high-density lipoprotein (HDL). Its N-terminal sequence is identical with that of amyloid A protein (AA), the subunit of AA amyloid fibrils. However, rats do not develop AA amyloidosis, and we report here that neither normal nor acute-phase rat HDL contains a protein corresponding to SAA of other species. mRNA coding for a sequence homologous with the C-terminal but not with the N-terminal part of human SAA is synthesized in greatly increased amounts in acute-phase rat liver. These observations indicate that the failure of rats to develop AA amyloid results from the absence of most of the AA-like part of their SAA-like protein, and that the N-terminal portion of SAA probably contains the lipid-binding sequences.


1993 ◽  
Vol 26 (6) ◽  
pp. 505-511 ◽  
Author(s):  
Yoshitaka Kumon ◽  
Tadashi Suehiro ◽  
Yukio Ikeda ◽  
Kenzo Yoshida ◽  
Kozo Hashimoto ◽  
...  

1986 ◽  
Vol 261 (21) ◽  
pp. 9644-9651 ◽  
Author(s):  
G A Coetzee ◽  
A F Strachan ◽  
D R van der Westhuyzen ◽  
H C Hoppe ◽  
M S Jeenah ◽  
...  

2012 ◽  
Vol 287 (30) ◽  
pp. 25669-25677 ◽  
Author(s):  
Fredrik Noborn ◽  
John B. Ancsin ◽  
Wimal Ubhayasekera ◽  
Robert Kisilevsky ◽  
Jin-Ping Li

2011 ◽  
Vol 31 (6) ◽  
pp. 1326-1332 ◽  
Author(s):  
Tsuyoshi Chiba ◽  
Mary Y. Chang ◽  
Shari Wang ◽  
Thomas N. Wight ◽  
Timothy S. McMillen ◽  
...  

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