scholarly journals Serum Amyloid A Facilitates the Binding of High-Density Lipoprotein From Mice Injected With Lipopolysaccharide to Vascular Proteoglycans

2011 ◽  
Vol 31 (6) ◽  
pp. 1326-1332 ◽  
Author(s):  
Tsuyoshi Chiba ◽  
Mary Y. Chang ◽  
Shari Wang ◽  
Thomas N. Wight ◽  
Timothy S. McMillen ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A

scholarly journals Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition.

1986 ◽  
Vol 261 (21) ◽  
pp. 9644-9651 ◽  
Author(s):  
G A Coetzee ◽  
A F Strachan ◽  
D R van der Westhuyzen ◽  
H C Hoppe ◽  
M S Jeenah ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Human High Density Lipoprotein

scholarly journals Heparan Sulfate Dissociates Serum Amyloid A (SAA) from Acute-phase High-density Lipoprotein, Promoting SAA Aggregation

2012 ◽  
Vol 287 (30) ◽  
pp. 25669-25677 ◽  
Author(s):  
Fredrik Noborn ◽  
John B. Ancsin ◽  
Wimal Ubhayasekera ◽  
Robert Kisilevsky ◽  
Jin-Ping Li
Keyword(s):  
High Density Lipoprotein ◽  
Heparan Sulfate ◽  
Acute Phase ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A

scholarly journals Marked Changes in Serum Amyloid A Distribution and High-Density Lipoprotein Structure during Acute Inflammation

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Shitsuko Shimano ◽  
Ryunosuke Ohkawa ◽  
Mayu Nambu ◽  
Mai Sasaoka ◽  
Azusa Yamazaki ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Surface Charge ◽  
Orthopedic Surgery ◽  
Acute Inflammation ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Apolipoprotein A

High-density lipoprotein- (HDL-) cholesterol measurements are generally used in the diagnosis of cardiovascular diseases. However, HDL is a complicated heterogeneous lipoprotein, and furthermore, it can be converted into dysfunctional forms during pathological conditions including inflammation. Therefore, qualitative analysis of pathophysiologically diversified HDL forms is important. A recent study demonstrated that serum amyloid A (SAA) can remodel HDL and induce atherosclerosis not only over long periods of time, such as during chronic inflammation, but also over shorter periods. However, few studies have investigated rapid HDL remodeling. In this study, we analyzed HDL samples from patients undergoing orthopedic surgery inducing acute inflammation. We enrolled 13 otherwise healthy patients who underwent orthopedic surgery. Plasma samples were obtained on preoperative day and postoperative days (POD) 1-7. SAA, apolipoprotein A-I (apoA-I), and apolipoprotein A-II (apoA-II) levels in the isolated HDL were determined. HDL particle size, surface charge, and SAA and apoA-I distributions were also analyzed. In every patient, plasma SAA levels peaked on POD3. Consistently, the HDL apoA-I : apoA-II ratio markedly decreased at this timepoint. Native-polyacrylamide gel electrophoresis and high-performance liquid chromatography revealed the loss of small HDL particles during acute inflammation. Furthermore, HDL had a decreased negative surface charge on POD3 compared to the other timepoints. All changes observed were SAA-dependent. SAA-dependent rapid changes in HDL size and surface charge were observed after orthopedic surgery. These changes might affect the atheroprotective functions of HDL, and its analysis can be available for the qualitative HDL assessment.

Serum Amyloid A Protein Generates Preβ1 High-Density Lipoprotein from α-Migrating High-Density Lipoprotein†

Biochemistry ◽  
1999 ◽  
Vol 38 (51) ◽  
pp. 16958-16962 ◽  
Author(s):  
Takashi Miida ◽  
Toshiyuki Yamada ◽  
Toru Yamadera ◽  
Kazuyuki Ozaki ◽  
Koichi Inano ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Serum Amyloid A Protein

scholarly journals High-Density Lipoprotein (HDL) Counter-Regulates Serum Amyloid A (SAA)-Induced sPLA2-IIE and sPLA2-V Expression in Macrophages

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0167468 ◽  
Author(s):  
Shu Zhu ◽  
Yongjun Wang ◽  
Weiqiang Chen ◽  
Wei Li ◽  
Angelina Wang ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A

scholarly journals A Role for the High-Density Lipoprotein Receptor SR-B1 in Synovial Inflammation via Serum Amyloid-A

2010 ◽  
Vol 176 (4) ◽  
pp. 1999-2008 ◽  
Author(s):  
Ronan Hugh Mullan ◽  
Jennifer McCormick ◽  
Mary Connolly ◽  
Barry Bresnihan ◽  
Douglas James Veale ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Synovial Inflammation ◽  
Serum Amyloid ◽  
Lipoprotein Receptor ◽  
Amyloid A ◽  
Density Lipoprotein Receptor

Preparation of anti-canine serum amyloid A (SAA) serum and purification of SAA from canine high-density lipoprotein

1994 ◽  
Vol 41 (1-2) ◽  
pp. 41-53 ◽  
Author(s):  
S. Yamamoto ◽  
S. Miyaji ◽  
Y. Ashida ◽  
K. Otabe ◽  
E. Momotani ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Serum Amyloid A ◽  
Density Lipoprotein ◽  
High Density ◽  
Serum Amyloid ◽  
Amyloid A ◽  
Canine Serum
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