Multilayers of a Globular Protein and a Weak Polyacid:  Role of Polyacid Ionization in Growth and Decomposition in Salt Solutions

2005 ◽  
Vol 6 (3) ◽  
pp. 1782-1788 ◽  
Author(s):  
Vladimir A. Izumrudov ◽  
Eugenia Kharlampieva ◽  
Svetlana A. Sukhishvili
1981 ◽  
Vol 241 (6) ◽  
pp. G469-G477 ◽  
Author(s):  
P. R. Kvietys ◽  
J. M. McLendon ◽  
D. N. Granger

In an autoperfused dog ileum preparation, artificial pressure, venous outflow pressure, blood flow, and arteriovenous oxygen difference were measured while bile and bile salt solutions, at physiological concentrations, were placed in the lumen. Intraluminal placement of endogenous bile, synthetic bile, or bile salt solutions increased ileal blood flow (99 +/- 10, 94 +/- 20, and 104 +/- 17%, respectively) and oxygen uptake (30 +/- 5, 36 +/- 9, and 28 +/- 5%, respectively). Endogenous bile pretreated with cholestyramine, a bile salt-sequestering resin, did not alter ileal blood flow, yet increased ileal oxygen uptake by 11 +/- 3%, a response similar to that observed while Tyrode's solution (the vehicle) was in the lumen. Intra-arterial infusion of bile salts increased ileal blood flow in a dose-dependent manner, while not significantly altering ileal oxygen uptake. The results of the present study indicate that bile salts play an important role in the functional (postprandial) hyperemia in the ileum by 1) directly dilating the ileal vasculature and 2) enhancing ileal metabolism during their active absorption.


2016 ◽  
Vol 120 (13) ◽  
pp. 7332-7338 ◽  
Author(s):  
Tuan Anh Pham ◽  
S. M. Golam Mortuza ◽  
Brandon C. Wood ◽  
Edmond Y. Lau ◽  
Tadashi Ogitsu ◽  
...  

2004 ◽  
Vol 87 (2) ◽  
pp. 1227-1240 ◽  
Author(s):  
Giuseppe Nicastro ◽  
Paola Margiocco ◽  
Barbara Cardinali ◽  
Paola Stagnaro ◽  
Fabio Cauglia ◽  
...  

2016 ◽  
Vol 18 (37) ◽  
pp. 25926-25936 ◽  
Author(s):  
Emmy C. Wijaya ◽  
Frances Separovic ◽  
Calum J. Drummond ◽  
Tamar L. Greaves

The role of solvent features on enzyme stability was investigated by comparing the conformation and activity of lysozyme in molecular solvents, PILs and salt solutions. Electrostatic interactions and the solvophobic effect dominated at low and high solvent concentrations, respectively.


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