Spectrophotometric Determination of 6-Propyl-2-thiouracil in Pharmaceutical Formulations Based on Prussian Blue Complex Formation: An Undergraduate Instrumental Analysis Laboratory Experiment

2015 ◽  
Vol 93 (1) ◽  
pp. 182-185
Author(s):  
Robert Zakrzewski ◽  
Monika Skowron ◽  
Witold Ciesielski ◽  
Żaneta Rembisz
2002 ◽  
Vol 28 (6) ◽  
pp. 1215-1220 ◽  
Author(s):  
Jadranka Kuljanin ◽  
Ivana Janković ◽  
Jovan Nedeljković ◽  
Dušica Prstojević ◽  
Valentina Marinković

Author(s):  
P. V. Lakshmana Rao ◽  
C. Rambabu

Objective: The authors report two simple, accurate and economic spectrophotometric methods A and B for the determination of Itopride hydrochloride in bulk and dosage forms.Methods: The proposed methods are based on the formation of chloroform soluble ion-associates in the presence of acidic dyes namely BPB (Method A) and BCP (Method B) exhibiting lmax at 418 and 418 nm respectively.Results: Beer’s law is found to be obeyed in the concentration range of 2.0-10.0 µg/ml and 2.0-10.0 µg/ml. The molar absorptivities are found to be 1.42x104 and 9.61x103L/mol. cm for methods A and B. These methods are successfully applied for the assay of Itopride hydrochloride in pharmaceutical formulations.


2010 ◽  
Vol 7 (1) ◽  
pp. 101-104 ◽  
Author(s):  
P. Baby Sudha Lakshmi ◽  
D. Ramchandran ◽  
C. Rambabu

Two simple, sensitive, selective and accurate spectro-photometric methods (Method A and Method B) for the determination of eztimibe in bulk drug and pharmaceutical formulations (tablets) have been described. Method A and B are based on the redox/complex formation reaction of drug with 1,10-phenanthroline and hexacyano-ferrate(III) in presence of ferric chloride to form coloured chromogens exhibitingλmaxat 510 and 740 nm respectively. The results of analysis for the two methods have been validated statistically and by recovery studies. The results are compared with those obtained using UV spectrophotometric method in alcohol at 231.7 nm.


1998 ◽  
Vol 75 (4) ◽  
pp. 450
Author(s):  
Siddharth Pandey ◽  
Mary E. R. McHale ◽  
Ann-Sofi M. Horton ◽  
Sandra A. Padilla ◽  
Ashantè L. Trufant ◽  
...  

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