scholarly journals Electrochemistry and Electrogenerated Chemiluminescence of a Spirobifluorene-Based Donor (Triphenylamine)−Acceptor (2,1,3-Benzothiadiazole) Molecule and Its Organic Nanoparticles

2011 ◽  
Vol 133 (14) ◽  
pp. 5492-5499 ◽  
Author(s):  
Khalid M. Omer ◽  
Sung-Yu Ku ◽  
Jian-Zhang Cheng ◽  
Shu-Hua Chou ◽  
Ken-Tsung Wong ◽  
...  



Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4127
Author(s):  
Aline de Cristo Soares Alves ◽  
Franciele Aline Bruinsmann ◽  
Silvia Stanisçuaski Guterres ◽  
Adriana Raffin Pohlmann

Bevacizumab (BCZ) is a recombinant humanized monoclonal antibody against the vascular endothelial growth factor, which is involved in the angiogenesis process. Pathologic angiogenesis is observed in several diseases including ophthalmic disorders and cancer. The multiple administrations of BCZ can cause adverse effects. In this way, the development of controlled release systems for BCZ delivery can promote the modification of drug pharmacokinetics and, consequently, decrease the dose, toxicity, and cost due to improved efficacy. This review highlights BCZ formulated in organic nanoparticles providing an overview of the physicochemical characterization and in vitro and in vivo biological evaluations. Moreover, the main advantages and limitations of the different approaches are discussed. Despite difficulties in working with antibodies, those nanocarriers provided advantages in BCZ protection against degradation guaranteeing bioactivity maintenance.





2020 ◽  
Vol 22 (27) ◽  
pp. 15413-15417 ◽  
Author(s):  
Andrea Fiorani ◽  
Giovanni Valenti ◽  
Irkham ◽  
Francesco Paolucci ◽  
Yasuaki Einaga

In this work, we quantify the electrogenerated chemiluminescence arising from the reaction of electrogenerated tris(bipyridine)ruthenium(iii) with hydroxyl ions, in terms of emission intensity and reaction rate.



2016 ◽  
Vol 88 (15) ◽  
pp. 7853-7857 ◽  
Author(s):  
Suying Xu ◽  
Xilin Bai ◽  
Jingwen Ma ◽  
Minmin Xu ◽  
Gaofei Hu ◽  
...  


The Analyst ◽  
2013 ◽  
Vol 138 (7) ◽  
pp. 2038 ◽  
Author(s):  
Jiezhen Li ◽  
Niya Wang ◽  
ThanhThuy Tran.T ◽  
Chen'an Huang ◽  
Lan Chen ◽  
...  


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