Solubility and Equilibrium Data of Phenol-Water-Isoamyl Acetate and Phenol-Water-Methyl Isobutyl Ketone Systems at 30° C.

1962 ◽  
Vol 7 (4) ◽  
pp. 457-460 ◽  
Author(s):  
K. S. Narasimhan ◽  
C. C. Reddy ◽  
K. S. Chari
Keyword(s):  
Methyl Isobutyl Ketone ◽  
Isoamyl Acetate ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Equilibrium Data ◽  
Phenol Water

Vapor-Liquid Equilibrium for Binary Systems of Methyl Ethyl Ketone and Methyl Isobutyl Ketone

2012 ◽  
Vol 550-553 ◽  
pp. 2616-2620
Author(s):  
Xiao Li ◽  
Yun Ren Qiu
Keyword(s):  
Temperature Variation ◽  
Methyl Isobutyl Ketone ◽  
Methyl Ethyl ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Liquid Equilibrium ◽  
Vapor Liquid Equilibrium ◽  
Equilibrium Data ◽  
The Mean ◽  
Vapor Liquid

Atmospheric vapor-liquid equilibrium data of methyl ethyl ketone (MEK) - methyl isobutyl ketone (MIBK) were measured using an improved Rose still and were used to recover the parameters of NRTL and UNIQUAC models. The results show that the simulated results agree well with the experimental data. The mean temperature variation is 0.14 °C and the mean mole fraction variation is 0.0023 using UNIQUAC model while the mean temperature variation is 0.17 °C and the mean mole fraction variation is 0.0025 using NRTL model. Both models can be used to calculate the atmospheric vapor-liquid equilibrium data of MEK - MIBK.

scholarly journals Pengaruh pH dan Jenis Pelarut terhadap Ekstraksi Batch Asam 6-Aminopenisilinat

2020 ◽  
Vol 18 (2) ◽  
pp. 61
Author(s):  
Lienda Aliwarga ◽  
Reynard Reynard ◽  
Iga Putri Yasmani ◽  
Mia Puspasari
Keyword(s):  
Methyl Isobutyl Ketone ◽  
Volume Ratio ◽  
Extraction Process ◽  
Isoamyl Acetate ◽  
Penicillin Acylase ◽  
Raw Material ◽  
Penicillin G ◽  
Optimum Process ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone

Abstrak. Asam 6-aminopenisilinat (6-APA) merupakan bahan dasar pembuatan penisilin semi-sintetis. Dalam skala komersial, 6-APA dapat diproduksi dengan cara enzimatis atau kimiawi. Pada umumnya, produksi 6-APA dilakukan secara enzimatis, yaitu dengan mengkonversi penisilin G menjadi 6-APA dengan bantuan penisilin asilase. Karena konversi merupakan reaksi kesetimbangan, maka produk yang didapat adalah campuran penisilin G, 6-APA, dan asam fenil asetat (PAA) sehingga untuk memperoleh 6-APA murni dilakukan proses ekstraksi, pemekatan, dan kristalisasi. Proses ini dipengaruhi oleh beberapa variabel operasi, yaitu temperatur, pH, dan jenis pelarut. Dalam penelitian ini akan dipelajari pengaruh pH dan jenis pelarut terhadap proses pemisahan 6-APA. Temperatur operasi adalah kondisi ruang dan perbandingan volume pelarut dengan volume larutan yang akan diekstraksi adalah 1:1. Variasi pH ekstraksi dilakukan antara rentang 2,0-5,0, sedangkan jenis pelarut yang digunakan adalah n-butil asetat, iso butil asetat, metil isobutil keton, dan iso amil asetat. Rentang pH terbaik untuk pemisahan 6-APA adalah 2,0-3,0 dengan pelarut metil isobutil keton. Pada kondisi ini, perolehan penisilin G adalah 98%, 6-APA 5%, dan PAA 99%. Sebagian besar 6-APA pada fase aquatik dapat diproses untuk pemurnian selanjutnya. Kata kunci: Penisilin G, 6-APA, PAA, ekstraksi, pelarut, pH. Abstract. Influence of pH and Solvent Types on 6-Aminopenicillinic Acid Batch Extraction. 6-aminopenicillinic acid (6-APA) is the raw material for producing semi-synthetic penicillin. In commercial scale, penicillin G is converted into 6-APA enzymatically by penicillin acylase. Due to the nature of equilibrium reaction, the products are in mixture solution of penicillin G, 6-APA, and phenyl acetic acid (PAA). In order to purify the targeted 6-APA, steps of extraction, concentration, and crystallisation are thereby compulsory. Extraction process is influenced by operation variables, among other things, temperature, pH, and solvent types. In this experiment, we observed the aspects of pH and solvent type, while temperature was set in room condition. Volume ratio of solvent to extracted solution was 1:1 and pH was varied between 2.0 and 5.0. There were four solvents tested: n-butyl acetate, isobutyl acetate, methyl isobutyl ketone, and isoamyl acetate. The results suggested that optimum process was attained from pH 2.0 to 3.0, using methyl isobutyl ketone as solvent. In this regard, the yield of penicillin G (98%), 6-APA 95%) and PAA (99%); hence, most of the 6-APA was concentrated within the aquatic phase, representing the ease of further process. Keywords: Penicillin G, 6-APA, PAA, extraction, solvent, pH. Graphical Abstract

Liquid–liquid equilibrium data for water + acetic acid + solvent (dichloromethane + methyl isobutyl ketone) at T = 301.15 K

2017 ◽  
Vol 67 ◽  
pp. 125-132 ◽  
Author(s):  
M. Timedjeghdine ◽  
A. Hasseine ◽  
H. Binous ◽  
O. Bacha ◽  
M. Attarakih
Keyword(s):  
Acetic Acid ◽  
Methyl Isobutyl Ketone ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Liquid Equilibrium ◽  
Equilibrium Data

Determination of Some Nitrophenols by Atomic Absorption Spectrometry (AAS) After Extraction of Ionic Associates Involving the Bipyridylocopper(II) or Phenanthrolinocopper(II) Complex

1994 ◽  
Vol 59 (10) ◽  
pp. 2227-2234 ◽  
Author(s):  
Václav Stužka ◽  
Jaromír Souček
Keyword(s):  
Molecular Weight ◽  
Atomic Absorption Spectrometry ◽  
Atomic Absorption ◽  
Methyl Isobutyl Ketone ◽  
Absorption Spectrometry ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Indirect Determination ◽  
Ionic Associates

A new method has been developed for the indirect determination of nitroso- and nitrophenols by atomic absorption spectrometry (AAS) after extraction of ionic associates involving bipyridylocopper(II) (CuDP) or phenanthrolinocopper(II) (CuPH) complexes. Nitrobenzene and methyl isobutyl ketone appeared to be suitable for the extraction. It was possible to determine several tenths to hundredths of a milligram of nitrophenol in a litre. Extractable associates with CuDP and CuPH are formed by phenols possessing two substituents or by higher molecular weight phenols such as naphthol or hydroxyquinoline. Monosubstituted phenols fail to form associates of this kind.

Ce and Ca/Nb doped Pd-mesocellular foam catalysts for gas-phase conversion of acetone to methyl isobutyl ketone

2021 ◽  
pp. 111169
Author(s):  
Kalina Grzelak ◽  
Rouzana Pulikkal Thumbayil ◽  
Søren Kegnæs ◽  
Maciej Trejda ◽  
Anders Riisager
Keyword(s):  
Gas Phase ◽  
Methyl Isobutyl Ketone ◽  
Phase Conversion ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone

Ternary vapour-liquid equilibria in the system: benzene-cyclohexane-methyl isobutyl ketone

1958 ◽  
Vol 9 (1) ◽  
pp. 69-73 ◽  
Author(s):  
P. Dakshinamurty ◽  
G. Jayarama Rao ◽  
M.V.R. Acharya ◽  
C. Venkata Rao
Keyword(s):  
Methyl Isobutyl Ketone ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone

Densities and refractive indexes of binary mixtures in the system methyl isobutyl ketone-2-butanol. Mathematical relations obtained

1980 ◽  
Vol 25 (4) ◽  
pp. 318-320 ◽  
Author(s):  
Roque Riggio ◽  
Mariana Hernandez Ubeda ◽  
Juan F. Ramos ◽  
Hector E. Martinez
Keyword(s):  
Binary Mixtures ◽  
Methyl Isobutyl Ketone ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Mathematical Relations
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