Rational Design and Enantioselective Synthesis of (1R,4S,5R,6S)-3-Azabicyclo[3.3.0]octane-4,6-dicarboxylic Acid A Novel Inhibitor at Human Glutamate Transporter Subtypes 1, 2, and 3

2006 ◽  
Vol 49 (1) ◽  
pp. 172-178 ◽  
Author(s):  
Lennart Bunch ◽  
Birgitte Nielsen ◽  
Anders A. Jensen ◽  
Hans Bräuner-Osborne
Keyword(s):  
Dicarboxylic Acid ◽  
Rational Design ◽  
Glutamate Transporter ◽  
Enantioselective Synthesis

Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

2019 ◽  
Vol 2 (6) ◽  
pp. 504-513 ◽  
Author(s):  
Yong-Bin Wang ◽  
Peiyuan Yu ◽  
Zhi-Peng Zhou ◽  
Jian Zhang ◽  
Jun (Joelle) Wang ◽  
...  
Keyword(s):  
Rational Design ◽  
Enantioselective Synthesis ◽  
Axially Chiral ◽  
Catalytic Applications

Enantioselective Synthesis of the Excitatory Amino Acid (1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic Acid

2002 ◽  
Vol 67 (22) ◽  
pp. 7613-7617 ◽  
Author(s):  
Daniel M. Bradley ◽  
Renameditswe Mapitse ◽  
Nicholas M. Thomson ◽  
Christopher J. Hayes
Keyword(s):  
Amino Acid ◽  
Dicarboxylic Acid ◽  
Excitatory Amino Acid ◽  
Enantioselective Synthesis

Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

2021 ◽  
Vol 23 (1) ◽  
pp. 219-228
Author(s):  
Nabanita Saikia ◽  
Mohamed Taha ◽  
Ravindra Pandey
Keyword(s):  
Nucleic Acid ◽  
Boron Nitride ◽  
Nucleic Acids ◽  
Dynamic Stability ◽  
Peptide Nucleic Acid ◽  
Rational Design ◽  
Peptide Nucleic Acids ◽  
Boron Nitride Nanotubes ◽  
Molecular Hybrids ◽  
Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

Catalytic enantioselective synthesis of indolizino[8,7-b]indole alkaloid derivatives based on the tandem reaction of tertiary enamides

2021 ◽  
Author(s):  
Xin-Ming Xu ◽  
Ming Xie ◽  
Jiazhu Li ◽  
Mei-Xiang Wang
Keyword(s):  
Indole Alkaloid ◽  
Enantioselective Synthesis ◽  
High Yield ◽  
Tandem Reaction ◽  
Indole Derivatives

An exquisite Pybox/Cu(OTf)2-catalyzed asymmetric tandem reaction of tertiary enamides was developed, which enabled the expeditious synthesis of indolizino[8,7-b]indole derivatives in high yield, excellent enantioselectivity and diastereoselectivity.

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