Structure–Activity Relationship (SAR) Optimization of 6-(Indol-2-yl)pyridine-3-sulfonamides: Identification of Potent, Selective, and Orally Bioavailable Small Molecules Targeting Hepatitis C (HCV) NS4B

2013 ◽  
Vol 57 (5) ◽  
pp. 2121-2135 ◽  
Author(s):  
Nanjing Zhang ◽  
Xiaoyan Zhang ◽  
Jin Zhu ◽  
Anthony Turpoff ◽  
Guangming Chen ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Small Molecules ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Orally Bioavailable

Large-scale structure-activity relationship study of hepatitis C virus NS5B polymerase inhibition using SMILES-based descriptors

2015 ◽  
Vol 19 (4) ◽  
pp. 955-964 ◽  
Author(s):  
Apilak Worachartcheewan ◽  
Virapong Prachayasittikul ◽  
Alla P. Toropova ◽  
Andrey A. Toropov ◽  
Chanin Nantasenamat
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Large Scale ◽  
Large Scale Structure ◽  
Structure Activity Relationship ◽  
Scale Structure ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study ◽  
Ns5b Polymerase
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