Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents

2008 ◽  
Vol 51 (19) ◽  
pp. 6055-6066 ◽  
Author(s):  
Xinrong Tian ◽  
Adrian G. Switzer ◽  
Steve A. Derose ◽  
Rajesh K. Mishra ◽  
Mark G. Solinsky ◽  
...  
Keyword(s):  
Receptor Agonists ◽  
Melanocortin 4 Receptor ◽  
Orally Bioavailable ◽  
Antiobesity Agents

scholarly journals Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways

2007 ◽  
Vol 6 (5) ◽  
pp. 398-405 ◽  
Author(s):  
Ligang Zhou ◽  
Gregory M. Sutton ◽  
Justin J. Rochford ◽  
Robert K. Semple ◽  
Daniel D. Lam ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Signaling Pathways ◽  
Receptor Signaling ◽  
Serotonin 2C Receptor ◽  
Receptor Agonists ◽  
Melanocortin 4 Receptor

Novel Melanocortin-4 Receptor Agonists That Decrease Food Intake and Body Weight

2009 ◽  
pp. 485-486 ◽  
Author(s):  
Jesse Z. Dong ◽  
Daniel B. DeOliveira ◽  
Heather A. Halem ◽  
John E. Taylor ◽  
Pierre Roubert ◽  
...  
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Decrease Food Intake ◽  
Receptor Agonists ◽  
Melanocortin 4 Receptor

Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists

2011 ◽  
Vol 21 (6) ◽  
pp. 1748-1753 ◽  
Author(s):  
Takao Kiyoi ◽  
Julia M. Adam ◽  
John K. Clark ◽  
Keneth Davies ◽  
Anna-Marie Easson ◽  
...  
Keyword(s):  
Cb1 Receptor ◽  
Cannabinoid Cb1 Receptor ◽  
Receptor Agonists ◽  
Orally Bioavailable

Melanocortin-4 receptor agonists alleviate intestinal dysfunction in secondary intra-abdominal hypertension rat model

2015 ◽  
Vol 195 (1) ◽  
pp. 263-270 ◽  
Author(s):  
Dong Liu ◽  
Hong-Guang Zhang ◽  
Ming-Tao Chang ◽  
Yang Li ◽  
Lian-Yang Zhang
Keyword(s):  
Rat Model ◽  
Receptor Agonists ◽  
Melanocortin 4 Receptor ◽  
Abdominal Hypertension
Sign in / Sign up

Export Citation Format

Share Document