Asymmetric Synthesis of 4- and 5-Substituted Pipecolic Esters by Ring-Closing Metathesis and Palladium-Catalyzed Formate Reduction

2008 ◽  
Vol 73 (17) ◽  
pp. 6877-6880 ◽  
Author(s):  
Chong-Si Sun ◽  
Yu-Shiang Lin ◽  
Duen-Ren Hou
Keyword(s):  
Asymmetric Synthesis ◽  
Ring Closing Metathesis ◽  
Palladium Catalyzed

Synthesis of fluorinated donepezil by palladium-catalyzed decarboxylative allylation of α-fluoro-β-keto ester with tri-substituted heterocyclic alkene and the self-disproportionation of its enantiomers

RSC Advances ◽  
2016 ◽  
Vol 6 (88) ◽  
pp. 85058-85062 ◽  
Author(s):  
Mayaka Maeno ◽  
Hiroya Kondo ◽  
Etsuko Tokunaga ◽  
Norio Shibata
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Asymmetric Synthesis ◽  
Therapeutic Agent ◽  
The Self ◽  
Keto Ester ◽  
Catalytic Asymmetric Synthesis ◽  
Palladium Catalyzed ◽  
Catalytic Asymmetric ◽  
Decarboxylative Allylation

Catalytic asymmetric synthesis of fluorinated donepezil, a promising new therapeutic agent for Alzheimer's disease, was achieved.

Asymmetric Synthesis of β-Lactam via Palladium-Catalyzed Enantioselective Intramolecular C(sp3)–H Amidation

ACS Catalysis ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 114-120 ◽  
Author(s):  
Hua-Rong Tong ◽  
Wenrui Zheng ◽  
Xiaoyan Lv ◽  
Gang He ◽  
Peng Liu ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Palladium Catalyzed

Palladium-Catalyzed Asymmetric Synthesis of Axially Chiral Allenylsilanes and Their Application to SE2′ Chirality Transfer Reactions

2010 ◽  
Vol 12 (24) ◽  
pp. 5736-5739 ◽  
Author(s):  
Masamichi Ogasawara ◽  
Atsushi Okada ◽  
Velusamy Subbarayan ◽  
Sebastian Sörgel ◽  
Tamotsu Takahashi
Keyword(s):  
Asymmetric Synthesis ◽  
Transfer Reactions ◽  
Chirality Transfer ◽  
Axially Chiral ◽  
Palladium Catalyzed
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