Asymmetric Synthesis of β-Lactam via Palladium-Catalyzed Enantioselective Intramolecular C(sp3)–H Amidation

ACS Catalysis ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 114-120 ◽  
Author(s):  
Hua-Rong Tong ◽  
Wenrui Zheng ◽  
Xiaoyan Lv ◽  
Gang He ◽  
Peng Liu ◽  
...  
RSC Advances ◽  
2016 ◽  
Vol 6 (88) ◽  
pp. 85058-85062 ◽  
Author(s):  
Mayaka Maeno ◽  
Hiroya Kondo ◽  
Etsuko Tokunaga ◽  
Norio Shibata

Catalytic asymmetric synthesis of fluorinated donepezil, a promising new therapeutic agent for Alzheimer's disease, was achieved.


2010 ◽  
Vol 12 (24) ◽  
pp. 5736-5739 ◽  
Author(s):  
Masamichi Ogasawara ◽  
Atsushi Okada ◽  
Velusamy Subbarayan ◽  
Sebastian Sörgel ◽  
Tamotsu Takahashi

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