Minor-Groove Binding Drugs: Where Is the Second Hoechst 33258 Molecule?

The Journal of Physical Chemistry B ◽

10.1021/jp400418w ◽

2013 ◽

Vol 117 (19) ◽

pp. 5820-5830 ◽

Author(s):

Louise H. Fornander ◽

Lisha Wu ◽

Martin Billeter ◽

Per Lincoln ◽

Bengt Nordén

Keyword(s):

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

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Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.

The EMBO Journal ◽

10.1002/j.1460-2075.1992.tb05045.x ◽

1992 ◽

Vol 11 (1) ◽

pp. 225-232 ◽

Author(s):

M. Sriram ◽

G.A. van der Marel ◽

H.L. Roelen ◽

J.H. van Boom ◽

A.H. Wang

Keyword(s):

Molecular Structure ◽

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

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Drugs and Minor Groove Binding in B-DNA: Netropsin and Hoechst 33258

Nucleic Acids and Molecular Biology ◽

10.1007/978-3-642-46596-3_1 ◽

1987 ◽

pp. 1-24 ◽

Author(s):

M. L. Kopka ◽

P. E. Pjura ◽

D. S. Goodsell ◽

R. E. Dickerson

Keyword(s):

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

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Association of the Minor Groove Binding Drug Hoechst 33258 with d(CGCGAATTCGCG)2: Volumetric, Calorimetric, and Spectroscopic Characterizations†

Biochemistry ◽

10.1021/bi047374f ◽

2005 ◽

Vol 44 (28) ◽

pp. 9785-9794 ◽

Author(s):

Feixue Han ◽

Nicolas Taulier ◽

Tigran V. Chalikian

Keyword(s):

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

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Nuclear magnetic resonance probing of binding interactions used by minor groove binding, DNA-directed ligands: assignment of the binding site of Hoechst 33258 on the self-complementary oligonucleotide, d(CGCGAATTCGCG)

Journal of the Chemical Society Chemical Communications ◽

10.1039/c39890001023 ◽

1989 ◽

pp. 1023 ◽

Author(s):

John A. Parkinson ◽

Jill Barber ◽

Kenneth T. Douglas ◽

John Rosamund ◽

Derek Sharples

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Binding Site ◽

Minor Groove ◽

The Self ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Binding Interactions ◽

Complementary Oligonucleotide

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Induced fit DNA recognition by a minor groove binding analogue of Hoechst 33258: fluctuations in DNA A tract structure investigated by NMR and molecular dynamics simulations

Nucleic Acids Research ◽

10.1093/nar/29.3.693 ◽

2001 ◽

Vol 29 (3) ◽

pp. 693-702 ◽

Author(s):

C. E. Bostock-Smith

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulations ◽

Dna Recognition ◽

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Induced Fit ◽

Dynamics Simulations ◽

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Salt Effects on Fluorescence Spectral Shifts of DNA-Bound Hoechst 33258 and Reaction Volumes of the Minor Groove Binding

Bulletin of the Chemical Society of Japan ◽

10.1246/bcsj.72.1129 ◽

1999 ◽

Vol 72 (5) ◽

pp. 1129-1137 ◽

Author(s):

Guo-Qing Tang ◽

Naoki Tanaka ◽

Shigeru Kunugi

Keyword(s):

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Salt Effects ◽

Spectral Shifts ◽

Reaction Volumes

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759. The DNA Minor Groove Binding Agents Hoechst 33258 and 33342 Enhance Recombinant Adeno-Associated Virus (rAAV) Transgene Expression

Molecular Therapy ◽

10.1016/j.ymthe.2004.06.755 ◽

2004 ◽

Vol 9 ◽

pp. S289

Keyword(s):

Transgene Expression ◽

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Adeno Associated Virus ◽

Dna Minor Groove ◽

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Effects of Pressure on the DNA Minor Groove Binding of Hoechst 33258

Bulletin of the Chemical Society of Japan ◽

10.1246/bcsj.71.1725 ◽

1998 ◽

Vol 71 (7) ◽

pp. 1725-1730 ◽

Author(s):

Guo-Qing Tang ◽

Naoki Tanaka ◽

Shigeru Kunugi

Keyword(s):

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Dna Minor Groove

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Solid-Phase Synthesis of Positively Charged Deoxynucleic Guanidine (DNG) Tethering a Hoechst 33258 Analogue: Triplex and Duplex Stabilization by Simultaneous Minor Groove Binding

Journal of the American Chemical Society ◽

10.1021/ja031557s ◽

2004 ◽

Vol 126 (12) ◽

pp. 3736-3747 ◽

Author(s):

Putta Mallikarjuna Reddy ◽

Thomas C. Bruice

Keyword(s):

Solid Phase Synthesis ◽

Solid Phase ◽

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Phase Synthesis ◽

Positively Charged

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Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1994.tb18917.x ◽

1994 ◽

Vol 222 (3) ◽

pp. 721-726 ◽

Author(s):

M. Cristina VEGA ◽

Isabel GARCIA SAEZ ◽

Joan AYMAMI ◽

Ramon ERITJA ◽

Gijs A. MAREL ◽

...

Keyword(s):

Crystal Structure ◽

Three Dimensional ◽

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Dna Dodecamer ◽

Dimensional Crystal

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