scholarly journals Analysis of MALDI-TOF Mass Spectrometry Data for Discovery of Peptide and Glycan Biomarkers of Hepatocellular Carcinoma†

2008 ◽  
Vol 7 (2) ◽  
pp. 603-610 ◽  
Author(s):  
Habtom W. Ressom ◽  
Rency S. Varghese ◽  
Lenka Goldman ◽  
Yanming An ◽  
Christopher A. Loffredo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Hepatocellular Carcinoma ◽  
Mass Spectrometry Data ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof

scholarly journals Quantifying Peptide Signal in MALDI-TOF Mass Spectrometry Data

2005 ◽  
Vol 4 (12) ◽  
pp. 1990-1999 ◽  
Author(s):  
Timothy W. Randolph ◽  
Bree L. Mitchell ◽  
Dale F. McLerran ◽  
Paul D. Lampe ◽  
Ziding Feng
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectrometry Data ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof

scholarly journals Software Solutions for Indication and Identification of Pathogenic Microoranisms Using Time-of-Flight Mass Spectrometry

2021 ◽  
pp. 40-50
Author(s):  
D. V. Ul’shina ◽  
D. A. Kovalev ◽  
I. V. Kuznetsova ◽  
O. V. Bobrysheva ◽  
T. L. Krasovskaya ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Programming Language ◽  
Time Of Flight ◽  
Mass Spectrometric ◽  
Mass Spectrometry Data ◽  
Spectrometric Analysis ◽  
Spectrometric Data ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof ◽  
Flight Mass Spectrometry

The effectiveness of differentiation of bacterial pathogens using MALDI-TOF mass spectrometry depends on the quality of sample preparation, compliance with mass spectrometric analysis parameters and statistical approaches used, implemented by various modern software tools. The review provides a brief description of the most known software used in the processing and bioinformation analysis of time-of-flight mass spectrometry data. A list of computer platforms, programs and environments, both commercial and publicly available, is presented. The results of indication and identification of pathogens of particularly dangerous and natural-focal infections by MALDI-TOF mass spectrometry using publicly available software – programming language R, Mass-Up, MicrobeMS, licensed – MatLab, ClinProTools, as well as free web applications, including, Speclust, Ribopeaksare provided. The data on usage of such well-known platforms as MALDI BioTyper, SARAMIS Vitek-MS and Andromas (Andromas SAS, France) for inter- and intra-specific differentiation of closely related species are presented. Results of identification and differentiation of microorganisms applying MALDI-TOF mass spectrometry based on detection of specific proteins for cross-comparison – biomarkers – are given. The analysis shows that the programming language R environment is one of the publicly available universal platforms with an optimal combination of algorithms for processing and interpreting of a large array of mass spectrometric data.

ANALYSIS OF MALDI-TOF MASS SPECTROMETRY DATA FOR DETECTION OF GLYCAN BIOMARKERS

2007 ◽  
Author(s):  
HABTOM W. RESSOM ◽  
RENCY S VARGHESE ◽  
LENKA GOLDMAN ◽  
CHRISTOPHER A LOFFREDO ◽  
MOHAMED ABDEL-HAMID ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectrometry Data ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof

Direct tissue analysis by MALDI-TOF mass spectrometry in human hepatocellular carcinoma

2011 ◽  
Vol 412 (3-4) ◽  
pp. 230-239 ◽  
Author(s):  
Eric C. Han ◽  
Ying-Shiung Lee ◽  
Wen-Sin Liao ◽  
Yu-Ching Liu ◽  
Hsin-Yi Liao ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Hepatocellular Carcinoma ◽  
Human Hepatocellular Carcinoma ◽  
Tissue Analysis ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof

A computational platform for MALDI-TOF mass spectrometry data: Application to serum and plasma samples

2010 ◽  
Vol 73 (3) ◽  
pp. 562-570 ◽  
Author(s):  
Dante Mantini ◽  
Francesca Petrucci ◽  
Damiana Pieragostino ◽  
Piero Del Boccio ◽  
Paolo Sacchetta ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectrometry Data ◽  
Plasma Samples ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof ◽  
Data Application ◽  
Computational Platform

The first synthesis of sandwich-type complex based on tetradiazepinoporphyrazine ligand

2014 ◽  
Vol 18 (01n02) ◽  
pp. 149-154 ◽  
Author(s):  
Ekaterina N. Tarakanova ◽  
Pavel A. Tarakanov ◽  
Victor E. Pushkarev ◽  
Larisa G. Tomilova
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Mass Spectrometry Data ◽  
Selective Synthesis ◽  
Maldi Tof Mass Spectrometry ◽  
H Nmr ◽  
Maldi Tof ◽  
Type Complex ◽  
Sandwich Type ◽  
First Time

Sandwich-type complex based on tetradiazepinoporphyrazine ligand — bis{tetrakis(5,7-di(4-tert-butylphenyl)-6H-1,4-diazepino)[2,3-b,g,l,q]porphyrazinato}lutetium — was synthesized for the first time. The structure of the compound has been confirmed by UV-vis/NIR, 1 H NMR spectroscopy, and MALDI-TOF mass spectrometry data. The introduction of annulated diazepine heterocycles to porphyrazine molecule significantly changes macrocycle reactivity and results in sandwich-type complex under conditions used for the selective synthesis of lanthanide(III) monophthalocyanines.

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