Reversal of Sodium Arsenite Inhibition of Rat Liver Microsomal Ca2+ Pumping ATPase by Vitamin C
Keyword(s):
Sodium arsenite (NaAsO2), at 10% of its median lethal dose, was administered to rats with and without vitamin C pretreatment. Liver microsomal fraction was isolated and the activity of Ca2+-ATPase was assayed. Sodium arsenite was found to inhibit the activity of the liver microsomal Ca2+-ATPase to 50% to that of control rats. The specific activity of the enzyme in rats administered sodium arsenite with vitamin C pretreatment was not significantly different from that of control rats.
1983 ◽
Vol 756
(1)
◽
pp. 72-82
◽
1973 ◽
Vol 1
(4)
◽
pp. 942-944
◽
Keyword(s):
2011 ◽
Vol 36
(3)
◽
pp. 159-166
◽
Keyword(s):
Keyword(s):